Detailed information NTG0160252

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ASU36_RS11435
• Genome accession: NZ_CP013137
• Coordinates: 2195948..2196835 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain XQ
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2190948..2201835

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASU36_RS11400 (ASU36_11400)	-	2190963..2191055 (+)	93	WP_010956583.1	hypothetical protein	-
ASU36_RS11405 (ASU36_11405)	-	2191163..2191660 (-)	498	WP_001065267.1	glutathione peroxidase	-
ASU36_RS11410 (ASU36_11410)	-	2191670..2191930 (-)	261	WP_014532715.1	hypothetical protein	-
ASU36_RS11415 (ASU36_11415)	-	2192312..2192425 (-)	114	WP_072357681.1	hypothetical protein	-
ASU36_RS11425 (ASU36_11425)	-	2193090..2195089 (-)	2000	Protein_2165	ABC transporter permease	-
ASU36_RS11430 (ASU36_11430)	-	2195086..2195841 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ASU36_RS11435 (ASU36_11435)	braS	2195948..2196835 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ASU36_RS11440 (ASU36_11440)	braR	2196846..2197511 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ASU36_RS11445 (ASU36_11445)	-	2197537..2197737 (-)	201	WP_000604725.1	hypothetical protein	-
ASU36_RS11455 (ASU36_11455)	-	2197935..2199359 (+)	1425	WP_058008252.1	alkaline phosphatase	-
ASU36_RS15520	-	2199419..2199520 (-)	102	WP_000731972.1	SE2200 family small protein	-
ASU36_RS11460 (ASU36_11460)	-	2199642..2200097 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ASU36_RS11465 (ASU36_11465)	-	2200342..2201103 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=160252 ASU36_RS11435 WP_000143420.1 2195948..2196835(-) (braS) [Staphylococcus aureus strain XQ]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=160252 ASU36_RS11435 WP_000143420.1 2195948..2196835(-) (braS) [Staphylococcus aureus strain XQ]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993