Detailed information NTG0160246

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ASU36_RS07375
• Genome accession: NZ_CP013137
• Coordinates: 1456558..1457601 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain XQ
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1451558..1462601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASU36_RS07345 (ASU36_07345)	-	1451979..1453235 (-)	1257	WP_001793428.1	aminopeptidase	-
ASU36_RS07350 (ASU36_07350)	-	1453238..1453438 (-)	201	WP_000180462.1	DUF1128 family protein	-
ASU36_RS07355 (ASU36_07355)	-	1453585..1454049 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ASU36_RS07360 (ASU36_07360)	-	1454056..1454331 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ASU36_RS07365 (ASU36_07365)	-	1454609..1455826 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
ASU36_RS07370 (ASU36_07370)	vraR	1455939..1456568 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ASU36_RS07375 (ASU36_07375)	vraS	1456558..1457601 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ASU36_RS07380 (ASU36_07380)	liaF	1457598..1458299 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
ASU36_RS07385 (ASU36_07385)	-	1458314..1458700 (-)	387	WP_001110179.1	hypothetical protein	-
ASU36_RS07390 (ASU36_07390)	map	1458917..1459675 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ASU36_RS07395 (ASU36_07395)	-	1460201..1461187 (+)	987	WP_000999713.1	FUSC family protein	-
ASU36_RS07400 (ASU36_07400)	-	1461376..1461789 (-)	414	WP_025174475.1	hypothetical protein	-
ASU36_RS07405 (ASU36_07405)	-	1461818..1461928 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=160246 ASU36_RS07375 WP_001017131.1 1456558..1457601(-) (vraS) [Staphylococcus aureus strain XQ]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=160246 ASU36_RS07375 WP_001017131.1 1456558..1457601(-) (vraS) [Staphylococcus aureus strain XQ]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCGGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1