Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FORC26_RS10380 Genome accession   NZ_CP013132
Coordinates   2010758..2011474 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain FORC_026     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2005758..2016474
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC26_RS10345 (FORC26_1777) - 2005974..2006600 (+) 627 WP_000522384.1 nitroreductase family protein -
  FORC26_RS10355 (FORC26_1778) - 2006961..2007746 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  FORC26_RS14605 hld 2008345..2008425 (-) 81 WP_000046023.1 delta-hemolysin -
  FORC26_RS10365 (FORC26_1779) - 2008715..2009278 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  FORC26_RS10370 (FORC26_1780) agrD 2009282..2009422 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  FORC26_RS10375 agrC 2009447..2010739 (+) 1293 WP_070957585.1 quorum-sensing sensor histidine kinase AgrC -
  FORC26_RS10380 (FORC26_1782) agrA 2010758..2011474 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  FORC26_RS10385 - 2011546..2011655 (+) 110 Protein_1883 hypothetical protein -
  FORC26_RS10390 (FORC26_1783) - 2011843..2012802 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  FORC26_RS10395 (FORC26_1784) - 2012799..2014283 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  FORC26_RS10400 (FORC26_1785) - 2014432..2015382 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=160188 FORC26_RS10380 WP_000688492.1 2010758..2011474(+) (agrA) [Staphylococcus aureus strain FORC_026]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=160188 FORC26_RS10380 WP_000688492.1 2010758..2011474(+) (agrA) [Staphylococcus aureus strain FORC_026]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment