Detailed information NTG0160187

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FORC26_RS09925
• Genome accession: NZ_CP013132
• Coordinates: 1931378..1932421 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FORC_026
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1926378..1937421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC26_RS09895 (FORC26_1701)	-	1926806..1928062 (-)	1257	WP_001793428.1	aminopeptidase	-
FORC26_RS09900 (FORC26_1702)	-	1928065..1928265 (-)	201	WP_000180460.1	DUF1128 family protein	-
FORC26_RS09905 (FORC26_1703)	-	1928412..1928876 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FORC26_RS09910 (FORC26_1704)	-	1928883..1929158 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FORC26_RS09915 (FORC26_1705)	-	1929436..1930647 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
FORC26_RS09920 (FORC26_1706)	vraR	1930759..1931388 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
FORC26_RS09925 (FORC26_1707)	vraS	1931378..1932421 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FORC26_RS09930 (FORC26_1708)	liaF	1932418..1933119 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FORC26_RS09935 (FORC26_1709)	-	1933134..1933520 (-)	387	WP_001110179.1	hypothetical protein	-
FORC26_RS09940 (FORC26_1710)	map	1933737..1934495 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FORC26_RS09955 (FORC26_1711)	-	1935026..1936012 (+)	987	WP_000999713.1	FUSC family protein	-
FORC26_RS09970 (FORC26_1712)	-	1936443..1936856 (-)	414	WP_001837236.1	hypothetical protein	-
FORC26_RS09975	-	1936885..1936996 (-)	112	Protein_1805	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=160187 FORC26_RS09925 WP_001017131.1 1931378..1932421(-) (vraS) [Staphylococcus aureus strain FORC_026]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=160187 FORC26_RS09925 WP_001017131.1 1931378..1932421(-) (vraS) [Staphylococcus aureus strain FORC_026]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1