Detailed information NTG0160023

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: SE1039_RS13325
• Genome accession: NZ_CP013114
• Coordinates: 2777245..2778594 (+)
• Length: 449 a.a.
• NCBI ID: WP_056936172.1
• Uniprot ID: -
• Organism: Staphylococcus equorum strain KS1039
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	2743869..2778594	2777245..2778594	within	0

Gene organization within MGE regions

Location: 2743869..2778594

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE1039_RS13205 (SE1039_26180)	ccrC	2743869..2745551 (-)	1683	WP_056936156.1	cassette chromosome recombinase CcrC	-
SE1039_RS13210 (SE1039_26200)	-	2745776..2747416 (-)	1641	WP_011302047.1	DUF5906 domain-containing protein	-
SE1039_RS13215 (SE1039_26210)	-	2747416..2747784 (-)	369	WP_041784734.1	hypothetical protein	-
SE1039_RS13220 (SE1039_26220)	-	2747777..2748877 (-)	1101	WP_056936157.1	DNA polymerase	-
SE1039_RS13225 (SE1039_26230)	-	2749088..2750413 (-)	1326	WP_056936158.1	DUF6038 family protein	-
SE1039_RS13230 (SE1039_26240)	-	2750494..2751225 (-)	732	WP_056936159.1	Cthe_2314 family HEPN domain-containing protein	-
SE1039_RS13235 (SE1039_26250)	-	2751416..2753122 (-)	1707	WP_056936160.1	ATP-dependent nuclease	-
SE1039_RS13240	-	2753697..2754519 (-)	823	Protein_2613	transposase	-
SE1039_RS13245 (SE1039_26270)	-	2754582..2756075 (+)	1494	WP_056936161.1	glycosyltransferase	-
SE1039_RS13250 (SE1039_26280)	galU	2756109..2756972 (+)	864	WP_056936162.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
SE1039_RS13255 (SE1039_26290)	-	2756990..2758636 (+)	1647	WP_056936163.1	phospho-sugar mutase	-
SE1039_RS13260 (SE1039_26310)	-	2758960..2759532 (-)	573	WP_046099807.1	GA module-containing protein	-
SE1039_RS13265 (SE1039_26320)	-	2759919..2762819 (-)	2901	WP_056936164.1	CDP-glycerol glycerophosphotransferase family protein	-
SE1039_RS13270 (SE1039_26330)	-	2762852..2765365 (-)	2514	WP_081035722.1	glycosyltransferase	-
SE1039_RS14050 (SE1039_26340)	-	2765384..2767144 (-)	1761	WP_230815309.1	accessory Sec system protein Asp2	-
SE1039_RS13280 (SE1039_26350)	-	2767991..2768464 (-)	474	WP_335337866.1	DUF6270 domain-containing protein	-
SE1039_RS13285 (SE1039_26360)	galU	2768576..2769448 (-)	873	WP_269465054.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
SE1039_RS13290 (SE1039_26370)	-	2769729..2770706 (-)	978	Protein_2623	DUF1002 domain-containing protein	-
SE1039_RS13295 (SE1039_26390)	-	2770747..2771496 (-)	750	WP_056936167.1	hypothetical protein	-
SE1039_RS13300 (SE1039_26400)	-	2771531..2772604 (-)	1074	WP_056936168.1	hypothetical protein	-
SE1039_RS13305 (SE1039_26410)	-	2772763..2772972 (-)	210	WP_047505035.1	PD-(D/E)XK nuclease family protein	-
SE1039_RS13310 (SE1039_26420)	-	2773401..2774828 (+)	1428	WP_056936169.1	DUF6038 family protein	-
SE1039_RS13315 (SE1039_26430)	cch1	2774954..2776747 (+)	1794	WP_056936170.1	cassette chromosome replicative helicase	-
SE1039_RS13320 (SE1039_26440)	-	2776810..2777067 (+)	258	WP_056936171.1	hypothetical protein	-
SE1039_RS13325 (SE1039_26450)	ccrA	2777245..2778594 (+)	1350	WP_056936172.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52351.02 Da
• Isoelectric Point: 9.9946

>NTDB_id=160023 SE1039_RS13325 WP_056936172.1 2777245..2778594(+) (ccrA) [Staphylococcus equorum strain KS1039]
MKQAMGYLRQSTTKQQSLAAQKQTIKALAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKLITTHAPFGYHYH
NGTFTIDTVKAPTVKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPDHSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINQTIQQRLKRQKDIETKSTLTQEQLIEKLARGKMDAGTFREQTQSLRQQSKPISSINAYQIKNAFQ
NIMQQRFTLNMLYPYIDEIHITKNKTLTGIYFKNEPLNIVNQTTQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=160023 SE1039_RS13325 WP_056936172.1 2777245..2778594(+) (ccrA) [Staphylococcus equorum strain KS1039]
ATGAAACAAGCAATGGGTTACTTACGACAGAGCACTACAAAGCAACAATCCTTAGCAGCACAAAAACAAACCATCAAGGC
ATTAGCCGAAAAACATAATATTCAACACATTACCTTTTATAGCGATAAACAATCAGGACGTACTGATAAGCGGAATGGTT
ACCAACAAATCACCGAACTAATTCAACAAGGACAATGTGACGTATTATGTTGCTATCGTCTAAATCGACTTCATCGTAAT
TTGAAAAATGCATTAAAACTCATGAAATTGTGTCAAAAATACCATGTCCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAACTGATTACAACACATGCACCCTTTGGGTATCACTATCAT
AATGGTACTTTCACGATAGACACAGTAAAAGCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATTCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTAAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGTCATTCGACACTCACAAACATGACTGTCCGAAAACCAGATCATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAGAACCAACAGCTCTATTCAAAAATTAACCAAACAATCCAACAACGACTCAAAAGACAAAAGGA
CATAGAAACAAAAAGTACACTCACACAAGAACAACTGATAGAAAAATTAGCCCGAGGCAAAATGGATGCAGGAACGTTCA
GAGAACAAACGCAATCATTACGCCAACAATCCAAACCTATATCATCCATCAATGCGTATCAAATCAAAAACGCTTTTCAA
AACATCATGCAACAACGTTTCACGTTAAACATGTTGTATCCCTACATTGATGAAATTCATATTACCAAAAACAAAACACT
TACGGGTATCTATTTCAAAAATGAGCCCTTAAACATCGTCAATCAAACAACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (170-249)

• Resolvase, N terminal domain (Resolvase) (4-147)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-322)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus COL	91.982	100	0.92
ccrA	Staphylococcus aureus N315	75.501	100	0.755