Detailed information    

insolico Bioinformatically predicted

Overview

Name   cqsS   Type   Regulator
Locus tag   NH62_RS02425 Genome accession   NZ_CP012997
Coordinates   549501..551561 (+) Length   686 a.a.
NCBI ID   WP_080387451.1    Uniprot ID   -
Organism   Vibrio cholerae strain 2012Env-9     
Function   autoinducer sensor (predicted from homology)   
Competence regulation

Genomic Context

Location: 544501..556561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NH62_RS02415 (NH62_10475) - 545222..546361 (+) 1140 WP_000670251.1 exonuclease SbcCD subunit D -
  NH62_RS02420 (NH62_10476) - 546363..549404 (+) 3042 WP_001247617.1 AAA family ATPase -
  NH62_RS02425 (NH62_10477) cqsS 549501..551561 (+) 2061 WP_080387451.1 quorum-sensing CAI-1 autoinducer sensor kinase/phosphatase CqsS Regulator
  NH62_RS02430 cqsA 551664..552834 (-) 1171 Protein_477 alpha-hydroxyketone-type quorum-sensing autoinducer synthase -
  NH62_RS02435 (NH62_10480) - 553031..553993 (-) 963 WP_001104009.1 TDT family transporter -
  NH62_RS02440 (NH62_10481) clcA 554140..555546 (-) 1407 WP_000107452.1 H(+)/Cl(-) exchange transporter ClcA -

Sequence

Protein


Download         Length: 686 a.a.        Molecular weight: 78436.20 Da        Isoelectric Point: 5.3925

>NTDB_id=159015 NH62_RS02425 WP_080387451.1 549501..551561(+) (cqsS) [Vibrio cholerae strain 2012Env-9]
MIVSMDVIKRVYQYAEPNLSLVGWMGMLGFPAYYFIWEYWFPQSYENLGLRCAAAVLFGGLVFRDSMPKKWQRYMPGYFL
FTIGFCLPFFFAFMMLMNDWSTIWAMSFMASIFLHILLVHDTRVMALQALFSVLVAYLAVYGLTDFHPTTLIEWQYIPIF
LFTYVFGNLCFFRNQISHETKVSIAKTFGAGIAHEMRNPLSALKTSIDVVRTMIPKPQTAAHTDYSLDAQELDLLHQILN
EADDVIYSGNNAIDLLLTSIDENRVSPASFKKHSVVDVIEKAVKTFPYKNAADQHSVELEVHQPFDFFGSDTLLTYALFN
LLKNAFYYQKEHFSVRISIEQTSEHNLIRVRDNGVGIAPEMLEDIFRDFYTFGKNGSYGLGLPFCRKVMSAFGGTIRCAS
QQGQWTEFVLSFPRYDSDTVNEIKTELLKTKSLIYIGSNQAIVRELNQLAVEDEFGFTAISAQQAVRRQDYEFEFDLILL
DLDDATAQGELLPKLEGTLSFAEGCIGYVYDPGKTYAVNINRYLRIQPISIHSILRKPRKIIERLLFEQESLSMNRNVIP
LQKSRHERRILVVDDNQSIRTFTAILLEQQGYEVVQANDGSEVLKHMESQNIDLVLMDIEMPNVGGLEATRLIRDSEHEY
KNIPIIGYTGDNSPKTLALVQTSGMNDFIVKPADRDVLLNKVAAWV

Nucleotide


Download         Length: 2061 bp        

>NTDB_id=159015 NH62_RS02425 WP_080387451.1 549501..551561(+) (cqsS) [Vibrio cholerae strain 2012Env-9]
GTGATAGTGAGCATGGATGTAATAAAGAGAGTGTATCAATACGCAGAACCTAATCTGTCCTTAGTCGGATGGATGGGCAT
GCTTGGCTTTCCTGCCTACTACTTCATCTGGGAATATTGGTTTCCGCAATCTTACGAAAATTTAGGGCTGCGCTGTGCGG
CAGCGGTGCTGTTTGGCGGGCTGGTGTTTCGTGATTCGATGCCTAAGAAATGGCAGCGGTATATGCCGGGCTATTTTCTA
TTCACCATAGGTTTCTGCTTACCCTTTTTCTTCGCTTTTATGATGTTAATGAACGACTGGTCGACAATTTGGGCCATGTC
GTTTATGGCGTCCATTTTTCTGCATATTCTCTTAGTGCACGATACGAGAGTGATGGCGTTACAAGCTCTTTTCTCAGTGT
TGGTGGCCTACCTTGCGGTATATGGTTTGACGGATTTTCACCCGACGACTTTGATTGAATGGCAATACATACCGATCTTT
TTGTTTACTTATGTATTTGGGAATTTATGTTTTTTCCGTAACCAAATCTCTCATGAGACCAAAGTGTCGATTGCCAAAAC
GTTCGGAGCGGGGATTGCCCATGAAATGCGTAATCCACTCAGCGCTTTGAAAACGTCGATTGATGTTGTGCGAACCATGA
TCCCTAAACCGCAAACTGCAGCTCATACGGATTATTCCTTGGATGCGCAAGAGCTGGATCTGCTGCATCAAATTTTGAAT
GAAGCTGATGATGTCATCTACTCTGGCAATAACGCGATTGATTTGCTGCTCACCTCGATTGATGAAAACCGCGTCTCTCC
GGCGAGTTTTAAAAAACACTCCGTAGTGGATGTGATTGAAAAAGCGGTGAAAACTTTTCCGTATAAAAATGCAGCGGACC
AGCACTCGGTAGAGCTTGAAGTGCATCAGCCGTTTGACTTTTTTGGCAGTGATACTCTACTGACTTATGCGCTATTTAAC
CTGTTGAAAAATGCCTTTTATTATCAAAAAGAGCATTTTTCAGTTCGTATTTCCATTGAACAAACCAGTGAGCATAACCT
TATTCGAGTCCGTGATAACGGCGTGGGGATTGCGCCAGAGATGTTGGAAGACATTTTCCGTGATTTCTATACCTTCGGTA
AAAATGGCAGCTATGGGCTAGGATTGCCATTTTGCCGCAAAGTGATGTCCGCATTTGGGGGGACGATTCGCTGTGCGTCT
CAACAAGGTCAATGGACAGAATTCGTATTGAGCTTTCCTCGTTACGATTCCGATACGGTTAACGAGATAAAAACAGAACT
GCTGAAAACCAAATCGCTCATTTATATCGGCTCAAATCAAGCTATCGTTCGAGAGTTAAATCAGCTCGCAGTAGAAGATG
AGTTTGGTTTTACCGCTATTTCTGCGCAGCAAGCAGTAAGACGCCAAGATTATGAGTTTGAGTTCGACCTTATTTTGCTC
GACCTTGATGACGCTACGGCGCAGGGAGAACTACTGCCGAAACTTGAAGGGACATTGAGTTTTGCAGAAGGCTGTATCGG
CTATGTGTATGACCCGGGTAAAACGTACGCGGTAAACATTAACCGTTATCTGCGTATCCAACCGATCAGTATTCACTCTA
TTCTCAGAAAGCCGCGGAAAATCATCGAACGCTTGTTGTTTGAGCAAGAATCCTTATCGATGAATCGTAACGTGATCCCC
TTGCAAAAGAGTCGGCATGAACGACGTATTTTGGTGGTTGATGATAATCAATCGATCCGAACTTTTACGGCTATTTTGCT
TGAGCAACAAGGTTATGAAGTGGTGCAAGCCAACGATGGTAGTGAAGTGCTCAAGCATATGGAGAGTCAAAACATCGATT
TAGTGTTGATGGACATTGAAATGCCGAATGTCGGGGGATTAGAAGCGACGCGTTTAATTCGCGACTCTGAGCATGAATAT
AAAAATATTCCGATCATTGGTTACACCGGTGATAACAGCCCCAAAACCTTGGCTCTGGTACAAACCTCCGGCATGAATGA
TTTCATTGTGAAGCCTGCTGACCGTGATGTATTGCTAAATAAAGTGGCAGCTTGGGTGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(570-682)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(312-413)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cqsS Vibrio cholerae strain A1552

99.708

100

0.997

Multiple sequence alignment