Detailed information NTG0158879

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAST41_RS12915
• Genome accession: NZ_CP012978
• Coordinates: 2578311..2579198 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain ST20130941
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2573311..2584198

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST41_RS12880	-	2573330..2573422 (+)	93	WP_010956583.1	hypothetical protein	-
SAST41_RS12885 (SAST41_02675)	-	2573530..2574027 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAST41_RS12890	-	2574037..2574297 (-)	261	WP_001791974.1	hypothetical protein	-
SAST41_RS12895	-	2574679..2574792 (-)	114	Protein_2450	hypothetical protein	-
SAST41_RS12905 (SAST41_03675)	-	2575451..2577451 (-)	2001	WP_000776740.1	ABC transporter permease	-
SAST41_RS12910 (SAST41_03676)	-	2577448..2578203 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAST41_RS12915 (SAST41_03960)	braS	2578311..2579198 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAST41_RS12920 (SAST41_02679)	braR	2579209..2579874 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAST41_RS12925 (SAST41_03678)	-	2579900..2580100 (-)	201	WP_000604727.1	hypothetical protein	-
SAST41_RS12935 (SAST41_02681)	-	2580298..2581722 (+)	1425	WP_000953748.1	alkaline phosphatase	-
SAST41_RS14330 (SAST41_03961)	-	2581782..2581883 (-)	102	WP_000731972.1	SE2200 family small protein	-
SAST41_RS12940 (SAST41_03962)	-	2582005..2582460 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAST41_RS12945 (SAST41_02684)	-	2582705..2583466 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=158879 SAST41_RS12915 WP_000143417.1 2578311..2579198(-) (braS) [Staphylococcus aureus strain ST20130941]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=158879 SAST41_RS12915 WP_000143417.1 2578311..2579198(-) (braS) [Staphylococcus aureus strain ST20130941]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99