Detailed information NTG0158837

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAST42_RS13445
• Genome accession: NZ_CP012976
• Coordinates: 2652173..2653060 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain ST20130942
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2647173..2658060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST42_RS13410	-	2647201..2647284 (+)	84	WP_031797553.1	hypothetical protein	-
SAST42_RS13415 (SAST42_02682)	-	2647392..2647889 (-)	498	WP_001065271.1	glutathione peroxidase	-
SAST42_RS13420	-	2647899..2648159 (-)	261	WP_001789307.1	hypothetical protein	-
SAST42_RS13425	-	2648541..2648654 (-)	114	WP_011447078.1	hypothetical protein	-
SAST42_RS13435 (SAST42_03133)	-	2649313..2651313 (-)	2001	WP_062909834.1	ABC transporter permease	-
SAST42_RS13440 (SAST42_03134)	-	2651310..2652065 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAST42_RS13445 (SAST42_04026)	braS	2652173..2653060 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAST42_RS13450 (SAST42_02688)	braR	2653071..2653736 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAST42_RS13455 (SAST42_03136)	-	2653762..2653962 (-)	201	WP_000604727.1	hypothetical protein	-
SAST42_RS13465 (SAST42_02690)	-	2654160..2655584 (+)	1425	WP_000953734.1	alkaline phosphatase	-
SAST42_RS14910 (SAST42_02691)	-	2655644..2655745 (-)	102	WP_000731976.1	SE2200 family small protein	-
SAST42_RS13470 (SAST42_04028)	-	2655867..2656322 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAST42_RS13475 (SAST42_02693)	-	2656567..2657328 (-)	762	WP_000323453.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=158837 SAST42_RS13445 WP_000143419.1 2652173..2653060(-) (braS) [Staphylococcus aureus strain ST20130942]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=158837 SAST42_RS13445 WP_000143419.1 2652173..2653060(-) (braS) [Staphylococcus aureus strain ST20130942]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997