Detailed information NTG0158797

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAST43_RS13445
• Genome accession: NZ_CP012974
• Coordinates: 2652240..2653127 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain ST20130943
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2647240..2658127

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST43_RS13410	-	2647268..2647351 (+)	84	WP_031797553.1	hypothetical protein	-
SAST43_RS13415 (SAST43_02675)	-	2647459..2647956 (-)	498	WP_001065271.1	glutathione peroxidase	-
SAST43_RS13420	-	2647966..2648226 (-)	261	WP_001789307.1	hypothetical protein	-
SAST43_RS13425	-	2648608..2648721 (-)	114	WP_011447078.1	hypothetical protein	-
SAST43_RS13435 (SAST43_03604)	-	2649380..2651380 (-)	2001	WP_062909834.1	ABC transporter permease	-
SAST43_RS13440 (SAST43_03605)	-	2651377..2652132 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAST43_RS13445 (SAST43_04063)	braS	2652240..2653127 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAST43_RS13450 (SAST43_02681)	braR	2653138..2653803 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAST43_RS13455 (SAST43_03607)	-	2653829..2654029 (-)	201	WP_000604727.1	hypothetical protein	-
SAST43_RS13465 (SAST43_04064)	-	2654227..2655651 (+)	1425	WP_000953734.1	alkaline phosphatase	-
SAST43_RS14910 (SAST43_02684)	-	2655711..2655812 (-)	102	WP_000731976.1	SE2200 family small protein	-
SAST43_RS13470 (SAST43_04066)	-	2655934..2656389 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAST43_RS13475 (SAST43_02686)	-	2656634..2657395 (-)	762	WP_000323453.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=158797 SAST43_RS13445 WP_000143419.1 2652240..2653127(-) (braS) [Staphylococcus aureus strain ST20130943]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=158797 SAST43_RS13445 WP_000143419.1 2652240..2653127(-) (braS) [Staphylococcus aureus strain ST20130943]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997