Detailed information NTG0158792

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAST43_RS09420
• Genome accession: NZ_CP012974
• Coordinates: 1900369..1901412 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ST20130943
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1895369..1906412

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST43_RS09390 (SAST43_03408)	-	1895791..1897047 (-)	1257	WP_001789555.1	aminopeptidase	-
SAST43_RS09395 (SAST43_01838)	-	1897050..1897250 (-)	201	WP_000180460.1	DUF1128 family protein	-
SAST43_RS09400 (SAST43_01839)	-	1897397..1897861 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SAST43_RS09405 (SAST43_01840)	-	1897868..1898143 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAST43_RS09410 (SAST43_01842)	-	1898421..1899638 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
SAST43_RS09415 (SAST43_03409)	vraR	1899750..1900379 (-)	630	WP_000153531.1	two-component system response regulator VraR	Regulator
SAST43_RS09420 (SAST43_01844)	vraS	1900369..1901412 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SAST43_RS09425 (SAST43_03410)	liaF	1901409..1902110 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SAST43_RS09430 (SAST43_01846)	-	1902125..1902511 (-)	387	WP_001110179.1	hypothetical protein	-
SAST43_RS09435 (SAST43_01847)	map	1902728..1903486 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAST43_RS09440 (SAST43_01848)	-	1903958..1904944 (+)	987	WP_000999720.1	FUSC family protein	-
SAST43_RS09445 (SAST43_04432)	-	1905375..1905788 (-)	414	WP_001566709.1	hypothetical protein	-
SAST43_RS09450	-	1905817..1905927 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=158792 SAST43_RS09420 WP_001017131.1 1900369..1901412(-) (vraS) [Staphylococcus aureus strain ST20130943]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=158792 SAST43_RS09420 WP_001017131.1 1900369..1901412(-) (vraS) [Staphylococcus aureus strain ST20130943]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1