Detailed information NTG0158758

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAST38_RS13250
• Genome accession: NZ_CP012972
• Coordinates: 2625684..2626571 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain ST20130938
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2620684..2631571

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST38_RS13215	-	2620703..2620795 (+)	93	WP_010956583.1	hypothetical protein	-
SAST38_RS13220 (SAST38_02712)	-	2620903..2621400 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAST38_RS13225	-	2621410..2621670 (-)	261	WP_001791974.1	hypothetical protein	-
SAST38_RS13230	-	2622052..2622165 (-)	114	Protein_2524	hypothetical protein	-
SAST38_RS13240 (SAST38_03565)	-	2622824..2624824 (-)	2001	WP_000776740.1	ABC transporter permease	-
SAST38_RS13245 (SAST38_03566)	-	2624821..2625576 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAST38_RS13250 (SAST38_04583)	braS	2625684..2626571 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAST38_RS13255 (SAST38_02716)	braR	2626582..2627247 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAST38_RS13260 (SAST38_03568)	-	2627273..2627473 (-)	201	WP_000604727.1	hypothetical protein	-
SAST38_RS13270 (SAST38_02718)	-	2627671..2629095 (+)	1425	WP_000953748.1	alkaline phosphatase	-
SAST38_RS14815 (SAST38_03954)	-	2629155..2629256 (-)	102	WP_000731972.1	SE2200 family small protein	-
SAST38_RS13275 (SAST38_03955)	-	2629378..2629833 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAST38_RS13280 (SAST38_02721)	-	2630078..2630839 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=158758 SAST38_RS13250 WP_000143417.1 2625684..2626571(-) (braS) [Staphylococcus aureus strain ST20130938]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=158758 SAST38_RS13250 WP_000143417.1 2625684..2626571(-) (braS) [Staphylococcus aureus strain ST20130938]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99