Detailed information NTG0158715

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAST39_RS13250
• Genome accession: NZ_CP012970
• Coordinates: 2625638..2626525 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain ST20130939
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2620638..2631525

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST39_RS13215	-	2620657..2620749 (+)	93	WP_010956583.1	hypothetical protein	-
SAST39_RS13220 (SAST39_02688)	-	2620857..2621354 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAST39_RS13225	-	2621364..2621624 (-)	261	WP_001791974.1	hypothetical protein	-
SAST39_RS13230	-	2622006..2622119 (-)	114	Protein_2521	hypothetical protein	-
SAST39_RS13240 (SAST39_03552)	-	2622778..2624778 (-)	2001	WP_000776740.1	ABC transporter permease	-
SAST39_RS13245 (SAST39_03553)	-	2624775..2625530 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAST39_RS13250 (SAST39_03915)	braS	2625638..2626525 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAST39_RS13255 (SAST39_02692)	braR	2626536..2627201 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAST39_RS13260 (SAST39_03555)	-	2627227..2627427 (-)	201	WP_000604727.1	hypothetical protein	-
SAST39_RS13270 (SAST39_02694)	-	2627625..2629049 (+)	1425	WP_000953748.1	alkaline phosphatase	-
SAST39_RS14790 (SAST39_03916)	-	2629109..2629210 (-)	102	WP_000731972.1	SE2200 family small protein	-
SAST39_RS13275 (SAST39_03917)	-	2629332..2629787 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAST39_RS13280 (SAST39_02697)	-	2630032..2630793 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=158715 SAST39_RS13250 WP_000143417.1 2625638..2626525(-) (braS) [Staphylococcus aureus strain ST20130939]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=158715 SAST39_RS13250 WP_000143417.1 2625638..2626525(-) (braS) [Staphylococcus aureus strain ST20130939]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99