Detailed information NTG0158573

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ASO12_RS02925
• Genome accession: NZ_CP016015
• Coordinates: 531750..534329 (-)
• Length: 859 a.a.
• NCBI ID: WP_047921588.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain 32867
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 526750..539329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASO12_RS02890 (ASO12_02890)	-	526784..527494 (-)	711	WP_003690977.1	phosphoglycolate phosphatase	-
ASO12_RS02905 (ASO12_02905)	-	527889..529108 (+)	1220	Protein_543	Glu/Leu/Phe/Val family dehydrogenase	-
ASO12_RS02910 (ASO12_02910)	-	529168..529974 (-)	807	WP_003690982.1	DUF4198 domain-containing protein	-
ASO12_RS02915 (ASO12_02915)	-	530166..530375 (+)	210	WP_003688192.1	tautomerase family protein	-
ASO12_RS02920 (ASO12_02920)	-	530464..531678 (+)	1215	WP_003690983.1	pyridoxal phosphate-dependent aminotransferase	-
ASO12_RS02925 (ASO12_02925)	clpC	531750..534329 (-)	2580	WP_047921588.1	ATP-dependent chaperone ClpB	Regulator
ASO12_RS02930 (ASO12_02930)	trpS	534589..535599 (+)	1011	WP_003690986.1	tryptophan--tRNA ligase	-
ASO12_RS02935 (ASO12_02935)	-	535680..536225 (+)	546	WP_003690987.1	hypothetical protein	-
ASO12_RS02940 (ASO12_02940)	-	536542..536886 (+)	345	WP_010358382.1	Ag473 family lipoprotein	-
ASO12_RS02945 (ASO12_02945)	-	537096..538604 (-)	1509	WP_003690989.1	Ppx/GppA phosphatase family protein	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95139.59 Da
• Isoelectric Point: 5.3090

>NTDB_id=158573 ASO12_RS02925 WP_047921588.1 531750..534329(-) (clpC) [Neisseria gonorrhoeae strain 32867]
MRYDKLTAKFQQALAEAQSLALVADSSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGE
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDVVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEIDGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGADEVAEIVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQNEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIKVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=158573 ASO12_RS02925 WP_047921588.1 531750..534329(-) (clpC) [Neisseria gonorrhoeae strain 32867]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGTTGCGGACAGCAG
CTATCTGGAAGCAGGTTTCGTACTGAAAGCCCTGCTTGACGACCAAAACAGCGGAGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTTAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGACAAGGTGGTGAG
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCGGCAACCAAACGCGGCGATGCCTATATCGC
CAGCGAACTTTTCCTGCTCGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATCTTGAAAGAAGCCGGTGCGACCGAAC
AAAACATCAATGCCGCGATCGATGTGGTACGAGGCGGACAAAACGTGAACGATGCGAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATACACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGTCGTGATGATGAAAT
CCGCCGCGCGATTCAGGTGCTGCAACGCCGCACCAAAAACAACCCCGTGCTGATTGGCGAACCCGGTGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCGCAACGCATCGTCAACGGCGAAGTACCTGAATCCCTGCGTAACAAACGCCTGCTGGTTTTG
GATTTGGCGGCTTTGATTGCCGGTGCGAAATACCGTGGCGAATTTGAAGAACGCTTGAAAGGCGTATTGAACGATTTGGC
GAAAGACGACGGCAACACCCTGATTTTCATCGATGAAATCCATACTTTGGTCGGCGCGGGCAAAACCGACGGCGCGATGG
ACGCGGGCAATATGTTGAAACCGGCCTTGGCGCGGGGCGAACTGCACTGTATCGGTGCGACTACTTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGTTTCCAAAAAGTATTGGTCGGCGAACCCAGCGTGGAAGACACCAT
CGCTATCCTGCGCGGTTTGCAGGAACGCTATGAAATCCACCACGGCATCGATATTACCGACCCCGCCATTGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTTTTGCCCGACAAGGCGATTGATTTGATTGACGAAGCTGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAACCGGAAGCTATGGACAAAATCGACCGCCGTTTGATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCGACGGCTTGCAAAAAG
AATACGCCGATTTGGACGAAATCTGGAAAGCCGAAAAAGCGATTTCAGACGGTGCTGCCAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCGGATGAAGTGGCCGAAATCGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGC
GATAAATTGTTGAAAATGGAAGAAGTGTTGCACCGCCGCGTAGTCGGTCAAAACGAAGCCGTGCGCGCCGTGTCCGATGC
CATCCGCCGCAGCCGCTCCGGCCTTGCCGATCCGAACAAACCTTACGGCAGCTTCCTGTTCTTAGGCCCGACCGGTGTGG
GTAAGACCGAGTTGTGCAAAGCTTTGGCAGGCTTCCTGTTCGACAGCGAAGACCACCTCATCCGCATCGACATGTCCGAA
TACATGGAAAAACACGCCGTTGCCCGCTTAATCGGCGCGCCTCCGGGTTATGTCGGATACGAAGAGGGCGGCTACCTGAC
CGAACAAGTCCGCCGCAAACCGTACAGCGTGATTCTTTTGGACGAAGTGGAAAAAGCCCATCCCGACGTATTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGACAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGCACGCAGGACTACGAAGCGGTGAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCGGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCATGGCTTGGATCAGGCCAATA
TCCGCAGTATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGAT
GCCGCTCTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCGATCCAATCGGA
AATCGAAAACCCGCTGGCCAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAAGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-442)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.465	100	0.455
clpC	Streptococcus pneumoniae TIGR4	39.532	100	0.413
clpC	Streptococcus pneumoniae D39	39.532	100	0.413
clpC	Streptococcus pneumoniae Rx1	39.532	100	0.413
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.274	100	0.403
clpC	Lactococcus lactis subsp. cremoris KW2	46.839	81.024	0.38
clpE	Streptococcus pneumoniae TIGR4	46.647	79.86	0.373
clpE	Streptococcus pneumoniae R6	46.501	79.86	0.371
clpE	Streptococcus pneumoniae D39	46.501	79.86	0.371
clpE	Streptococcus pneumoniae Rx1	46.501	79.86	0.371