Detailed information NTG0158225

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: APQ97_RS08305
• Genome accession: NZ_CP012911
• Coordinates: 1654908..1655957 (-)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain NSUI060
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1649908..1660957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APQ97_RS08285 (APQ97_08275)	nadE	1650736..1651560 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
APQ97_RS08290 (APQ97_08280)	-	1652434..1652961 (-)	528	WP_004194600.1	VanZ family protein	-
APQ97_RS08295 (APQ97_08285)	rlmN	1652958..1654070 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
APQ97_RS08300 (APQ97_08290)	-	1654079..1654720 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
APQ97_RS08305 (APQ97_08295)	sepM	1654908..1655957 (-)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
APQ97_RS08310 (APQ97_08300)	coaD	1655944..1656432 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
APQ97_RS08315 (APQ97_08305)	rsmD	1656422..1656961 (-)	540	WP_024394248.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
APQ97_RS08320 (APQ97_08310)	-	1657260..1657982 (-)	723	WP_013730502.1	hypothetical protein	-
APQ97_RS08325 (APQ97_08315)	-	1658039..1658425 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
APQ97_RS08330 (APQ97_08320)	-	1658425..1658643 (-)	219	WP_004194736.1	YqgQ family protein	-
APQ97_RS08335 (APQ97_08325)	-	1658943..1659545 (-)	603	WP_004194738.1	response regulator transcription factor	-
APQ97_RS08340 (APQ97_08330)	-	1659542..1660636 (-)	1095	WP_004194740.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=158225 APQ97_RS08305 WP_004194592.1 1654908..1655957(-) (sepM) [Streptococcus suis strain NSUI060]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=158225 APQ97_RS08305 WP_004194592.1 1654908..1655957(-) (sepM) [Streptococcus suis strain NSUI060]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605