Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   APV63_RS02595 Genome accession   NZ_CP012905
Coordinates   533959..535743 (-) Length   594 a.a.
NCBI ID   WP_060473080.1    Uniprot ID   -
Organism   Helicobacter pylori strain 7C     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 528959..540743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APV63_RS02565 (APV63_02565) - 529306..529554 (+) 249 WP_060473076.1 RNA-binding protein -
  APV63_RS02570 (APV63_02570) - 529782..530603 (-) 822 WP_060473077.1 glycosyltransferase family 25 protein -
  APV63_RS02575 (APV63_02575) trxB 530989..531924 (-) 936 WP_060473078.1 thioredoxin-disulfide reductase -
  APV63_RS02580 (APV63_02580) trxA 531929..532249 (-) 321 WP_000020199.1 thioredoxin -
  APV63_RS02585 (APV63_02585) - 532338..532682 (-) 345 WP_001211689.1 YraN family protein -
  APV63_RS02590 (APV63_02590) - 532683..533948 (-) 1266 WP_060473079.1 homoserine dehydrogenase -
  APV63_RS02595 (APV63_02595) uvrC 533959..535743 (-) 1785 WP_060473080.1 excinuclease ABC subunit UvrC Machinery gene
  APV63_RS02600 (APV63_02600) - 535744..536205 (-) 462 WP_060473081.1 hypothetical protein -
  APV63_RS02605 (APV63_02605) - 536197..536376 (+) 180 WP_060473082.1 hypothetical protein -
  APV63_RS02610 (APV63_02610) - 536388..537029 (-) 642 WP_060473083.1 ATP-binding cassette domain-containing protein -
  APV63_RS02615 (APV63_02615) - 537033..538694 (-) 1662 WP_060473084.1 ABC transporter permease/substrate-binding protein -
  APV63_RS02620 (APV63_02620) - 538763..539200 (-) 438 WP_000802458.1 hypothetical protein -
  APV63_RS02625 (APV63_02625) motB 539206..539979 (-) 774 WP_060473085.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68647.80 Da        Isoelectric Point: 9.5845

>NTDB_id=158172 APV63_RS02595 WP_060473080.1 533959..535743(-) (uvrC) [Helicobacter pylori strain 7C]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDWILEEARSLFNLECVPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKNSYRCYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGTKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=158172 APV63_RS02595 WP_060473080.1 533959..535743(-) (uvrC) [Helicobacter pylori strain 7C]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCACAATAATGAAATCACGCCCA
ACCATCGTGCAAGCTTACGCATTCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACGATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAGTTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATTAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGACATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GCTTGTTCTAATGAAGTGCTTAAAGAATTGCAAGAATTTATCTCCCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATTGGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTCCAAAAAAACTCTTATCGGTG
CTACCATTTGAAAGGCTCTAATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTAATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGTGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCACTAAAGACATCAT
CCATACGCCTAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTGAAAAAACGAAATTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.133

99.832

0.97

Multiple sequence alignment