Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   A9E94_RS01910 Genome accession   NZ_CP015954
Coordinates   425367..428222 (+) Length   951 a.a.
NCBI ID   WP_010946133.1    Uniprot ID   Q5ZYI8
Organism   Legionella pneumophila strain E7_O     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 420367..433222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9E94_RS01885 (A9E94_01885) - 421167..422621 (-) 1455 WP_010946128.1 RimK family protein -
  A9E94_RS01890 (A9E94_01890) - 422625..423338 (-) 714 WP_015444858.1 C39 family peptidase -
  A9E94_RS01895 (A9E94_01895) - 423533..424006 (-) 474 WP_010946130.1 DUF4442 domain-containing protein -
  A9E94_RS01900 (A9E94_01900) - 424003..424554 (-) 552 WP_015444857.1 BON domain-containing protein -
  A9E94_RS01905 (A9E94_01905) - 424813..425271 (-) 459 WP_015444856.1 hypothetical protein -
  A9E94_RS01910 (A9E94_01910) uvrA 425367..428222 (+) 2856 WP_010946133.1 excinuclease ABC subunit UvrA Machinery gene
  A9E94_RS01915 (A9E94_01915) - 428405..428986 (+) 582 WP_010946134.1 LemA family protein -
  A9E94_RS01920 (A9E94_01920) htpX 428997..430016 (+) 1020 WP_010946135.1 zinc metalloprotease HtpX -
  A9E94_RS01925 (A9E94_01925) - 430043..430816 (-) 774 WP_010946136.1 ABC transporter permease -
  A9E94_RS01930 (A9E94_01930) - 430806..431720 (-) 915 WP_010946137.1 ABC transporter ATP-binding protein -
  A9E94_RS01935 (A9E94_01935) vipA 431951..433009 (-) 1059 WP_010946139.1 Dot/Icm T4SS effector VipA -

Sequence

Protein


Download         Length: 951 a.a.        Molecular weight: 105494.15 Da        Isoelectric Point: 6.6446

>NTDB_id=158030 A9E94_RS01910 WP_010946133.1 425367..428222(+) (uvrA) [Legionella pneumophila strain E7_O]
MHTITIRGARTHNLKNLDLELPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSMMEKPDVDSIEGLS
PAISIEQKATSHNPRSTVGTITEIYDYLRLLYARVGEPRCPTHHTSLHAQTISQMVDQVLALPEDSKVMILAPVIRERKG
EHVQFLQQLQAQGYVRARIDGELYELDSPPKLGLRTKHTIEVVIDRFKVRPDLAQRLSESFENALNLADGLVIVSSMDGH
FNELLFSSRFACSECGYSLSELEPRLFSFNNPVGACSSCDGLGVDQFFDPSRVVHDATASLAEGAIRGWDRKTTYYFSML
ESLARHYGFDTSTPFCDLSEAMQQIVLYGSGREIIEFQYHRPHGGYMVKRHSFEGIIPNMQRRYRESDSGMIREELAKYL
SSRPCQSCQGARLREEARHVFIDNKNLPEITSYSIEQAYQFFKELKLSGYRGEIAAKINKEIVERLGFLVNVGLDYLSLA
RSAETLSGGEAQRIRLASQIGSGLVGVMYILDEPSIGLHQRDNDRLLSTLMHLRNQGNTVIVVEHDEDAIRSADFVLDIG
PGAGVHGGEVVASGSPEEVMNNPASLTGQYLSGKKEIEIPKDRIPVNHDRMIHLKGVSCNNLQNVDVSIPLGLLTCITGV
SGSGKSSLINDTLYPIAANALNRASLMTIGEVKDISGLHLCDKVIDIDQSPIGRTPRSNPATYTGLFTHIRDLFSGTPES
RARGYQPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVSCDVCQGKRYNRETLEIHYKGKNIHEVLDMTVEDACAFFA
AIPVIARKCLTLMDVGLSYIKLGQSATTLSGGEAQRIKLARELSKRDTGNTLYILDEPTTGLHFHDTKQLLTVLTRLREQ
GNTIVIIEHNLDVIKTADWIVDLGPEGGSKGGKIIATGTPEMVAENPQSFTGQFLRQILSKSNELLLQKCK

Nucleotide


Download         Length: 2856 bp        

>NTDB_id=158030 A9E94_RS01910 WP_010946133.1 425367..428222(+) (uvrA) [Legionella pneumophila strain E7_O]
ATGCATACCATCACCATTCGTGGCGCAAGAACCCATAATCTCAAGAACTTGGACCTGGAGCTTCCTCGAGATAAATTAAT
CGTAATAACCGGATTGTCTGGTTCTGGGAAGTCGTCTTTAGCCTTTGATACTCTCTATGCCGAAGGCCAGCGCCGTTACG
TGGAATCTTTGTCTGCTTATGCTCGACAATTTTTGTCCATGATGGAAAAACCTGATGTTGATTCGATAGAGGGGCTCTCC
CCGGCGATTTCTATAGAACAAAAGGCTACCTCTCATAATCCCCGATCCACGGTAGGCACCATTACCGAAATTTATGACTA
TTTGCGCTTGCTTTATGCCCGAGTCGGAGAGCCAAGGTGTCCTACCCACCACACCAGCTTGCATGCTCAGACCATTAGTC
AAATGGTTGATCAGGTATTGGCTTTACCAGAAGACAGTAAAGTGATGATTCTGGCGCCTGTTATTCGTGAACGGAAGGGA
GAGCATGTCCAGTTTTTGCAACAATTGCAAGCGCAAGGGTACGTACGTGCACGTATTGATGGAGAGCTTTATGAACTGGA
TTCTCCCCCTAAATTAGGATTGCGTACCAAGCACACTATTGAAGTAGTTATTGATCGCTTTAAAGTACGCCCTGATTTGG
CTCAACGTTTGAGTGAATCTTTTGAAAATGCGCTCAATCTGGCAGATGGTCTTGTCATCGTTTCTTCAATGGATGGTCAT
TTCAATGAACTTTTATTTTCTTCAAGGTTTGCATGCTCTGAATGCGGTTACAGTTTAAGTGAACTTGAGCCAAGGCTTTT
TTCATTTAACAATCCTGTCGGTGCATGTTCCTCATGTGATGGGCTTGGAGTGGATCAGTTTTTTGATCCGTCAAGAGTAG
TCCACGATGCAACCGCCAGTTTGGCAGAAGGGGCAATCAGGGGATGGGATAGGAAAACCACGTATTATTTCAGCATGCTT
GAGTCGCTTGCGAGGCACTATGGTTTTGATACCAGTACGCCTTTTTGTGATTTAAGTGAAGCAATGCAACAAATCGTTTT
GTATGGTAGTGGTCGTGAAATAATCGAGTTTCAGTATCATAGGCCGCATGGAGGATACATGGTTAAGCGGCATAGTTTTG
AGGGAATAATTCCTAACATGCAACGCCGCTATCGTGAATCAGATTCTGGTATGATAAGGGAGGAACTTGCCAAATACCTA
TCCTCACGCCCTTGCCAATCTTGCCAGGGAGCGAGATTGCGTGAAGAAGCTCGACATGTATTTATTGATAATAAAAATCT
ACCAGAAATCACCAGCTATTCTATTGAGCAAGCCTATCAGTTTTTTAAAGAGCTGAAGTTATCGGGGTATAGGGGTGAAA
TTGCAGCAAAAATCAATAAGGAAATTGTTGAGCGGCTGGGGTTTCTGGTGAATGTCGGGCTAGATTATTTGTCTTTGGCT
CGAAGCGCGGAGACTCTATCTGGCGGAGAAGCTCAACGTATTCGCCTGGCTAGTCAAATAGGTTCAGGGCTTGTAGGGGT
GATGTATATTTTGGATGAGCCTTCAATAGGGCTGCACCAACGTGACAATGACCGATTATTGAGTACTTTAATGCATTTAC
GCAACCAGGGAAACACTGTAATCGTTGTCGAACATGATGAAGATGCTATCCGAAGCGCTGATTTTGTTCTTGATATAGGG
CCTGGGGCTGGAGTGCATGGTGGGGAAGTAGTTGCCAGCGGTTCTCCTGAAGAGGTAATGAACAATCCCGCATCTCTCAC
CGGCCAATATTTGTCTGGGAAAAAGGAAATAGAAATTCCCAAGGATCGAATTCCGGTTAACCATGATCGGATGATTCATT
TAAAAGGCGTGTCTTGCAATAATTTACAAAATGTTGATGTCAGTATTCCTTTAGGTTTGTTGACTTGTATTACAGGTGTT
TCTGGTTCAGGTAAATCCAGTTTGATTAATGATACTTTATATCCTATTGCTGCCAATGCACTAAACAGAGCCAGCTTAAT
GACTATAGGTGAGGTTAAGGACATTTCTGGACTGCATCTTTGTGACAAGGTTATTGACATCGACCAGAGTCCAATTGGCA
GAACTCCGCGTTCCAATCCGGCAACTTATACTGGTTTATTTACTCATATCAGAGATTTATTCTCAGGGACTCCGGAATCA
AGAGCACGAGGGTATCAACCTGGGCGCTTTAGTTTCAATGTAAAAGGTGGCCGGTGCGAAGCTTGTCAAGGTGATGGTCT
TATCAAGGTTGAAATGCATTTTTTACCTGATATATACGTTTCTTGCGATGTATGCCAAGGCAAAAGATACAATAGGGAAA
CTTTGGAAATTCACTACAAAGGCAAAAATATTCATGAAGTGTTGGACATGACTGTCGAAGATGCGTGCGCTTTTTTTGCT
GCCATTCCTGTTATTGCCAGAAAATGCCTAACATTAATGGATGTCGGTTTGTCTTATATAAAGCTTGGACAAAGTGCAAC
TACTCTCTCTGGAGGAGAAGCTCAAAGGATCAAGTTGGCCAGAGAATTATCAAAAAGGGATACCGGAAATACACTATATA
TTCTCGATGAGCCCACAACAGGATTACACTTTCATGACACGAAACAGTTATTAACTGTGTTGACTCGCTTGCGAGAGCAA
GGAAATACCATTGTCATTATTGAACATAATTTGGATGTGATAAAAACGGCTGATTGGATCGTTGATCTTGGTCCTGAAGG
AGGCAGTAAAGGGGGAAAGATTATTGCAACAGGAACACCCGAAATGGTTGCTGAAAACCCTCAATCTTTTACAGGTCAGT
TTTTAAGACAAATTTTATCAAAATCAAATGAGCTTCTATTACAGAAATGCAAATAG

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(289-398)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5ZYI8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

58.591

98.528

0.577
  uvrA Streptococcus pneumoniae TIGR4

58.591

98.528

0.577
  uvrA Streptococcus pneumoniae D39

58.591

98.528

0.577

Multiple sequence alignment