Detailed information NTG0157726

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SanJ4211_RS08815
• Genome accession: NZ_CP012805
• Coordinates: 1756243..1758672 (-)
• Length: 809 a.a.
• NCBI ID: WP_021002164.1
• Uniprot ID: A0AAP6BRX0
• Organism: Streptococcus anginosus strain J4211
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1751243..1763672

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4211_RS08790 (SanJ4211_1744)	-	1751533..1752351 (+)	819	WP_057489829.1	hypothetical protein	-
SanJ4211_RS08795 (SanJ4211_1745)	-	1752369..1753640 (+)	1272	WP_021002160.1	toxic anion resistance protein	-
SanJ4211_RS08800 (SanJ4211_1746)	hslO	1753859..1754731 (+)	873	WP_003026496.1	Hsp33 family molecular chaperone HslO	-
SanJ4211_RS08805 (SanJ4211_1747)	dusB	1754718..1755689 (+)	972	WP_021002162.1	tRNA dihydrouridine synthase DusB	-
SanJ4211_RS08810 (SanJ4211_1748c)	-	1755760..1756200 (-)	441	WP_021002163.1	GNAT family N-acetyltransferase	-
SanJ4211_RS08815 (SanJ4211_1749c)	clpC	1756243..1758672 (-)	2430	WP_021002164.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SanJ4211_RS08820 (SanJ4211_1750c)	-	1758676..1759137 (-)	462	WP_021002165.1	CtsR family transcriptional regulator	-
SanJ4211_RS08825 (SanJ4211_1751)	-	1759397..1759747 (+)	351	WP_021002166.1	hypothetical protein	-

Sequence

Protein

• Length: 809 a.a.
• Molecular weight: 90028.24 Da
• Isoelectric Point: 6.2562

>NTDB_id=157726 SanJ4211_RS08815 WP_021002164.1 1756243..1758672(-) (clpC) [Streptococcus anginosus strain J4211]
MKYSKALTESIESAQLLASHFETDYLESWHLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKIYQQEGSFTIWPF
SHRMKVLFLTAERIAEAVHAKNLGTEHVLLAMLFDRGSLAARLLEFTGFSYEDKEGVLRMTDLRKNLEHKASWNKEDLKA
IRHLNKNAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHTGLLEPVIGRDKEISRMLQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKYIEKDAALSRRFAKITIEEPTVADSIAILQGLKKSYEEHHKVVITDSAIET
AVKYAHRYLTNKHLPDSAIDLLDEAAATVQNKGPQNHVKTELSAADEALMAGDWKKVGTLLEKESQPIVYKLKVKDEDIL
ATLSGLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMMEELKKAYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVKPLVSSLAEKGIKLKFQPSALKLLAQEGYDPEMGARPLRRTLQTQVEDHLSELLLAGELQMGQSLKVGVK
AGQLEFEVL

Nucleotide

• Length: 2430 bp

>NTDB_id=157726 SanJ4211_RS08815 WP_021002164.1 1756243..1758672(-) (clpC) [Streptococcus anginosus strain J4211]
ATGAAATATTCAAAAGCTTTGACAGAAAGTATTGAGTCGGCACAACTGTTAGCGAGTCATTTTGAAACGGATTATTTGGA
GTCTTGGCATTTGTTGATTGCCATGGCGAATAATCCTTATAGTGTTGCGGGCTCAGTTTTAAATGATTATCCGCTTGAAA
TTGATGATTTTGAGAAAGCAGCCTTTCATATCACAGGAAAGATTTATCAACAAGAGGGAAGCTTTACCATTTGGCCGTTT
TCTCATCGTATGAAAGTGTTGTTTTTGACAGCTGAGCGAATTGCAGAGGCTGTGCATGCTAAGAATCTTGGGACAGAGCA
TGTGTTATTAGCTATGCTGTTTGATCGAGGAAGTTTGGCGGCACGTCTCCTTGAATTCACAGGATTTAGCTATGAGGATA
AAGAAGGCGTTTTGCGCATGACCGATCTTCGGAAAAACTTAGAGCATAAGGCAAGCTGGAATAAAGAGGATTTAAAGGCG
ATTCGTCACCTAAATAAAAATGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAGTGG
CGGACTAGAAGATTATACTCGTGATTTAACCGAAATGGCTCATACGGGTCTTTTAGAACCGGTCATTGGGCGGGATAAAG
AGATTTCTCGCATGCTTCAGATTTTAAGTCGCAAGACGAAAAATAATCCAGTGTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCCCTTGGTTTGGCGCAACGTGTGGCAGCTGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGACATGTCATTCTTTTCATTGATGAGCTTCATACTATTATGGGGTCGGGTAGCGGGATTGACTCGACA
TTAGATGCAGCGAACATTCTCAAGCCAGCTTTGGCTAGAGGGACGCTCAGAACGGTCGGCGCAACGACACAAGAAGAGTA
CCAGAAATATATTGAAAAGGACGCAGCTCTTTCACGGCGATTTGCCAAAATTACTATTGAAGAGCCGACGGTAGCCGATA
GTATTGCGATTTTACAGGGGCTCAAGAAAAGTTATGAAGAACACCACAAAGTGGTGATTACAGATTCAGCGATTGAGACA
GCTGTTAAGTATGCTCATCGTTATCTAACAAATAAACATCTACCTGACTCGGCGATCGATTTGCTAGATGAAGCTGCCGC
AACGGTACAAAATAAAGGTCCGCAAAATCATGTAAAAACAGAATTGAGTGCAGCAGACGAGGCTTTAATGGCAGGCGATT
GGAAAAAGGTTGGCACTTTGTTGGAGAAAGAAAGTCAGCCAATTGTCTACAAACTAAAGGTTAAAGATGAGGATATTTTG
GCAACACTCAGCGGTTTATCGGGAATTCCTGTGCAAAAGTTGACGCAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAACTGCACAAGCGGGTCATTGGGCAAAATGAAGCAATTTCTGCTATTAGTCGAGCGATTCGGCGCAATCAATCCGGTA
TCCGCACTAGCAAGCGTCCAATTGGCTCCTTTATGTTCTTAGGGCCAACCGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCACTGATTCGTTTTGATATGAGTGAATACATGGAAAAATTTGCTGCCAG
TCGCCTCAATGGAGCGCCTCCAGGTTATGTTGGTTATGAAGAAGGGGGCGAATTAACTGAAAAAGTTCGCAATCGTCCGT
ACTCTGTACTCCTCTTTGATGAGGTAGAAAAAGCACATCCTGATATTTTCAATGTGCTTCTCCAAGTCTTAGATGACGGG
GTGCTGACAGACAGCAAGGGGCGTAAGGTGGATTTTTCCAATACCATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTGCGGGACGACAAGACGGTTGGTTTTGGAGCAAGAGATGTTCGTTTTGATCATGAAAATATGGAAAAACGAATGATGG
AAGAGCTAAAGAAAGCTTATCGTCCAGAATTTATTAACCGAATTGATGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAAGAAGTGGTAAAAATCATGGTGAAACCGCTCGTTTCTAGTCTTGCAGAAAAAGGAATTAAACTCAAATTCCA
GCCGAGTGCTTTGAAACTTCTGGCTCAAGAGGGTTATGACCCTGAAATGGGAGCTCGTCCACTGCGCAGAACTCTACAAA
CTCAGGTAGAAGATCATTTATCCGAATTACTTTTAGCTGGTGAGTTACAGATGGGACAAAGTTTGAAAGTCGGTGTCAAA
GCTGGACAGCTGGAGTTTGAAGTGCTATGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-797)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-350)

• AAA lid domain (AAA_lid_9) (371-439)

• AAA domain (Cdc48 subfamily) (AAA_2) (539-710)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-60)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (91-130)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	78.052	100	0.782
clpC	Streptococcus pneumoniae D39	78.052	100	0.782
clpC	Streptococcus pneumoniae TIGR4	78.052	100	0.782
clpC	Streptococcus mutans UA159	66.503	100	0.67
clpC	Streptococcus thermophilus LMG 18311	66.093	100	0.665
clpC	Streptococcus thermophilus LMD-9	65.971	100	0.664
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50	100	0.508
clpC	Bacillus subtilis subsp. subtilis str. 168	45.761	99.135	0.454