Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SanJ4211_RS02305 Genome accession   NZ_CP012805
Coordinates   443957..445258 (+) Length   433 a.a.
NCBI ID   WP_021001373.1    Uniprot ID   A0A0P0N797
Organism   Streptococcus anginosus strain J4211     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 438957..450258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS02290 - 441432..441953 (+) 522 WP_037590270.1 hypothetical protein -
  SanJ4211_RS02295 (SanJ4211_0428c) cysK 442237..443166 (-) 930 WP_021001371.1 cysteine synthase A -
  SanJ4211_RS02300 (SanJ4211_0429c) - 443265..443900 (-) 636 WP_021001372.1 YigZ family protein -
  SanJ4211_RS02305 (SanJ4211_0430) comFA/cflA 443957..445258 (+) 1302 WP_021001373.1 DEAD/DEAH box helicase Machinery gene
  SanJ4211_RS02310 (SanJ4211_0431) - 445255..445920 (+) 666 WP_003025757.1 ComF family protein -
  SanJ4211_RS02315 (SanJ4211_0432) hpf 445999..446541 (+) 543 WP_003025754.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SanJ4211_RS02320 (SanJ4211_0433) rsmD 446729..447277 (+) 549 WP_025271932.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SanJ4211_RS02325 (SanJ4211_0434) coaD 447267..447764 (+) 498 WP_021001374.1 pantetheine-phosphate adenylyltransferase -
  SanJ4211_RS02330 (SanJ4211_0435) sepM 447745..448800 (+) 1056 WP_021001375.1 SepM family pheromone-processing serine protease Regulator
  SanJ4211_RS02335 (SanJ4211_0436) - 448938..449504 (+) 567 WP_021001376.1 YutD family protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 48894.84 Da        Isoelectric Point: 8.8375

>NTDB_id=157688 SanJ4211_RS02305 WP_021001373.1 443957..445258(+) (comFA/cflA) [Streptococcus anginosus strain J4211]
MTELQDCLGRIFTKSQLSPELQLQAQTLAGMVEEKGKLSCNRCGQVIDKEKHQLPIGAYYCRSCLILGRVRSDEDLYYFP
QEEFPKANVLKWQGKLTAFQAKVSQGLVEAVAKRKNSLVHAVTGAGKTEMIYQVVAQVINQGGAVCLASPRIDVCLELYR
RLKVDFTCDISLLHGESEAYSRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPMLYHAVHQAVKVEGTKIFLTATS
TDELDKKVAKGELTRLSLPRRFHGNPLIVPQKIWLADFQKYLGQKKLVPKLRQFIQKQRKTGFPLLIFASEIRKGQELAE
ILQSTFPNEKVGFVASTTENRLEIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSME
RPTGELIFFHDGTTMAIEKAIKEIQEMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=157688 SanJ4211_RS02305 WP_021001373.1 443957..445258(+) (comFA/cflA) [Streptococcus anginosus strain J4211]
ATGACAGAATTACAAGATTGTTTAGGTCGCATTTTTACAAAAAGTCAACTGTCACCAGAATTACAATTGCAAGCACAAAC
CTTAGCTGGAATGGTAGAAGAAAAAGGGAAGTTAAGCTGCAATCGTTGTGGGCAAGTCATTGACAAAGAAAAACACCAAT
TGCCAATAGGTGCTTATTATTGCAGGTCTTGCTTGATCTTAGGAAGGGTCAGAAGTGATGAAGATCTTTACTATTTTCCA
CAGGAAGAATTTCCTAAAGCGAATGTCTTGAAATGGCAAGGGAAGTTGACAGCGTTTCAAGCCAAGGTTTCTCAAGGACT
TGTAGAGGCGGTTGCTAAACGAAAAAATAGCTTGGTTCACGCAGTCACGGGAGCCGGAAAGACGGAAATGATCTATCAGG
TGGTGGCACAAGTCATCAATCAAGGTGGAGCAGTCTGCTTGGCTAGTCCCAGAATTGATGTCTGCTTAGAACTTTATCGC
AGATTGAAAGTAGATTTTACTTGTGATATTTCACTCCTACACGGTGAATCAGAAGCATATTCCCGCAGTCCTCTCGTGAT
TGCCACCACACATCAGCTTCTCAAATTTTACCGAGCATTTGATCTTCTTATTGTTGATGAGGTAGATGCCTTTCCTTATG
TGGACAATCCGATGCTTTATCATGCAGTTCATCAGGCAGTCAAAGTAGAGGGGACGAAGATTTTCTTAACGGCAACTTCC
ACAGATGAGCTGGATAAAAAAGTGGCTAAAGGAGAATTAACTCGTTTGAGTCTACCCAGACGTTTTCATGGCAATCCTTT
GATTGTTCCGCAAAAAATTTGGTTGGCGGATTTTCAAAAATATCTTGGTCAAAAGAAGCTAGTTCCCAAGTTAAGGCAGT
TTATTCAAAAGCAGAGAAAAACAGGATTTCCACTTCTTATTTTTGCTTCCGAGATCAGAAAAGGGCAGGAGCTGGCAGAG
ATTCTTCAAAGCACTTTTCCTAATGAAAAAGTTGGTTTTGTAGCCTCGACGACTGAAAATCGACTAGAAATTGTAGAGAA
ATTTCGTCAAAAAGAAATCACGATTTTGGTAACGACGACGATTTTGGAGCGTGGGGTGACTTTTCCTTGTGTAGATGTTT
TCGTGGTGGAAGCCAACCACCGTCTGTTTAGTCGCAGCGCTCTGGTACAAATTGCTGGACGCGTTGGTCGCAGTATGGAG
CGACCGACAGGCGAGTTAATCTTTTTTCATGACGGTACGACTATGGCGATAGAAAAAGCGATTAAAGAAATTCAGGAGAT
GAATCAGGAGGCCGGTTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(108-245)

Helicase conserved C-terminal domain (Helicase_C)

(291-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0P0N797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

71.729

98.845

0.709
  comFA/cflA Streptococcus pneumoniae D39

71.729

98.845

0.709
  comFA/cflA Streptococcus pneumoniae R6

71.729

98.845

0.709
  comFA/cflA Streptococcus pneumoniae TIGR4

71.495

98.845

0.707
  comFA/cflA Streptococcus mitis NCTC 12261

71.596

98.383

0.704
  comFA/cflA Streptococcus mitis SK321

70.892

98.383

0.697
  comFA Lactococcus lactis subsp. cremoris KW2

55.528

91.917

0.51
  comFA Latilactobacillus sakei subsp. sakei 23K

40.698

99.307

0.404
  comFA Bacillus subtilis subsp. subtilis str. 168

40.247

93.533

0.376

Multiple sequence alignment