Detailed information NTG0157347

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: AN924_RS04570
• Genome accession: NZ_CP012731
• Coordinates: 933178..934131 (-)
• Length: 317 a.a.
• NCBI ID: WP_024409299.1
• Uniprot ID: A0A7Y6VE95
• Organism: Streptococcus suis strain 90-1330
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 928178..939131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AN924_RS04550 (AN924_09580)	pepA	928656..929717 (+)	1062	WP_002936538.1	glutamyl aminopeptidase	-
AN924_RS04555 (AN924_09590)	-	929763..931019 (-)	1257	WP_013730079.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
AN924_RS04560 (AN924_09610)	-	931030..931626 (-)	597	WP_009909104.1	folate family ECF transporter S component	-
AN924_RS04565 (AN924_09620)	-	931941..933128 (-)	1188	WP_013730078.1	acetate kinase	-
AN924_RS04570 (AN924_09630)	comYH	933178..934131 (-)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
AN924_RS04575 (AN924_09640)	comGG	934188..934598 (-)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
AN924_RS04580 (AN924_09650)	comGF/cglF	934576..935010 (-)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
AN924_RS04585 (AN924_09660)	comYE	934997..935290 (-)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
AN924_RS04590 (AN924_09670)	comGD	935262..935669 (-)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
AN924_RS04595 (AN924_09680)	comYC	935650..935931 (-)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
AN924_RS04600 (AN924_09690)	comYB	935933..936970 (-)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
AN924_RS04605 (AN924_09700)	comYA	936882..937832 (-)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
AN924_RS04610 (AN924_09710)	-	937918..938868 (+)	951	WP_002936565.1	S66 family peptidase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35807.97 Da
• Isoelectric Point: 4.4571

>NTDB_id=157347 AN924_RS04570 WP_024409299.1 933178..934131(-) (comYH) [Streptococcus suis strain 90-1330]
MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNAAYVANQHEMDLVVNNNKTLKQLDLTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLMPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARSLTPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI

Nucleotide

• Length: 954 bp

>NTDB_id=157347 AN924_RS04570 WP_024409299.1 933178..934131(-) (comYH) [Streptococcus suis strain 90-1330]
ATGAATTTTGAAAAGATCGAACAGGCTTACGACCTGCTATTAGAAAACGTACAGACTATCCAAAACCAGCTAGGTACCAA
TATCTATGATGCCATGATTGAGCAAAATGCTGCTTACGTAGCTAATCAGCATGAGATGGACCTTGTTGTCAATAATAACA
AGACCTTGAAACAACTAGATTTAACCAAGGAAGAATGGCGTCGTGCCTATCAATTCTTGCTCATCAAGGCCAATCAGACT
GAACCCATGCAGTACAATCACCAGTTCACACCAGACTCTATCGGATTTATCCTATCTTTTCTAGTAGACCAATTGATGCC
GACTCAAAAGGTGACGGTTCTGGAAATTGGTTCGGGGACAGGCAATCTAGCTCAGACCATTCTCAACGCCAGCCAGAAAG
AATTGGATTACTTGGGGATCGAAGTGGACGACCTCTTGATTGATTTGTCGGCAAGTATTGCGGATGTCATGCAGGCAGAT
ATTTCTTTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAGGAAAGTCAAGTAATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGCTATCAGGTCGCCAGCCCAAATGAACATACCTACGCCCATCATTTACTCA
TGGAACAATCCCTGAAATATCTGGAAAAAGATGGCTTTGCGATTTTGTTGGCTCCAAATGATTTATTGACTAGTCCGCAA
AGCGATTTGCTGAAAGGTTGGTTACAGGAGCAAGCCAATATTGTTGCCATGATTGCCCTGCCACCAAATCTCTTTGGGAA
GGCTGCTATGGCCAAGTCTATTTTTGTCTTGCAAAAGAAAGCTGCAAGATCGTTGACGCCGTTTGTTTATCCCTTACAAA
GTCTTCAAGAACCAGAAGCTATTCAGAAGTTCATGCTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-283)

3D structure

• AlphaFold DB: A0A7Y6VE95

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	60.759	99.685	0.606
comYH	Streptococcus mutans UA159	60.443	99.685	0.603