Detailed information NTG0157307

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: AOQ80_RS21370
• Genome accession: NZ_CP012730
• Coordinates: 4009453..4010247 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain Parent1
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4004453..4015247

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AOQ80_RS21350 (AOQ80_21340)	-	4006254..4006487 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
AOQ80_RS21355 (AOQ80_21345)	-	4006536..4007264 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
AOQ80_RS21360 (AOQ80_21350)	-	4007315..4007461 (+)	147	WP_001247671.1	YycC family protein	-
AOQ80_RS21365 (AOQ80_21355)	-	4007629..4009155 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
AOQ80_RS21370 (AOQ80_21360)	spo0A	4009453..4010247 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
AOQ80_RS21380 (AOQ80_21370)	spoIVB	4010535..4011833 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
AOQ80_RS21385 (AOQ80_21375)	recN	4011952..4013691 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
AOQ80_RS21390 (AOQ80_21380)	argR	4013959..4014408 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=157307 AOQ80_RS21370 WP_003161566.1 4009453..4010247(-) (spo0A) [Bacillus anthracis strain Parent1]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=157307 AOQ80_RS21370 WP_003161566.1 4009453..4010247(-) (spo0A) [Bacillus anthracis strain Parent1]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818