Detailed information NTG0157260

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: AOQ81_RS21360
• Genome accession: NZ_CP012729
• Coordinates: 4009445..4010239 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain Parent2
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4004445..4015239

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AOQ81_RS21340 (AOQ81_21330)	-	4006246..4006479 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
AOQ81_RS21345 (AOQ81_21335)	-	4006528..4007256 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
AOQ81_RS21350 (AOQ81_21340)	-	4007307..4007453 (+)	147	WP_001247671.1	YycC family protein	-
AOQ81_RS21355 (AOQ81_21345)	-	4007621..4009147 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
AOQ81_RS21360 (AOQ81_21350)	spo0A	4009445..4010239 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
AOQ81_RS21370 (AOQ81_21360)	spoIVB	4010527..4011825 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
AOQ81_RS21375 (AOQ81_21365)	recN	4011944..4013683 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
AOQ81_RS21380 (AOQ81_21370)	argR	4013951..4014400 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=157260 AOQ81_RS21360 WP_003161566.1 4009445..4010239(-) (spo0A) [Bacillus anthracis strain Parent2]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=157260 AOQ81_RS21360 WP_003161566.1 4009445..4010239(-) (spo0A) [Bacillus anthracis strain Parent2]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818