Detailed information NTG0156931

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: AOD63_RS21355
• Genome accession: NZ_CP012722
• Coordinates: 4009449..4010243 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain PR05
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4004449..4015243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AOD63_RS21335 (AOD63_21330)	-	4006250..4006483 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
AOD63_RS21340 (AOD63_21335)	-	4006532..4007260 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
AOD63_RS21345 (AOD63_21340)	-	4007311..4007457 (+)	147	WP_001247671.1	YycC family protein	-
AOD63_RS21350 (AOD63_21345)	-	4007625..4009151 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
AOD63_RS21355 (AOD63_21350)	spo0A	4009449..4010243 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
AOD63_RS21365 (AOD63_21360)	spoIVB	4010531..4011829 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
AOD63_RS21370 (AOD63_21365)	recN	4011948..4013687 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
AOD63_RS21375 (AOD63_21370)	argR	4013955..4014404 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=156931 AOD63_RS21355 WP_003161566.1 4009449..4010243(-) (spo0A) [Bacillus anthracis strain PR05]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=156931 AOD63_RS21355 WP_003161566.1 4009449..4010243(-) (spo0A) [Bacillus anthracis strain PR05]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818