Detailed information NTG0156613

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: AN159_RS09055
• Genome accession: NZ_CP012694
• Coordinates: 1711997..1713262 (+)
• Length: 421 a.a.
• NCBI ID: WP_002220091.1
• Uniprot ID: X5EMG2
• Organism: Neisseria meningitidis strain 331401
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1706997..1718262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AN159_RS09035 (AN159_09065)	-	1707728..1708729 (+)	1002	WP_002216162.1	thiamine ABC transporter substrate-binding protein	-
AN159_RS09040 (AN159_09070)	-	1708823..1709671 (+)	849	WP_002246544.1	mechanosensitive ion channel family protein	-
AN159_RS09045 (AN159_09075)	-	1709697..1710182 (+)	486	WP_002221794.1	CinA family protein	-
AN159_RS09050 (AN159_09080)	msrAB	1710284..1711852 (-)	1569	WP_069972524.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
AN159_RS09055 (AN159_09085)	pilA	1711997..1713262 (+)	1266	WP_002220091.1	signal recognition particle-docking protein FtsY	Machinery gene
AN159_RS09060 (AN159_09090)	-	1713851..1714135 (+)	285	WP_002246543.1	GIY-YIG nuclease family protein	-
AN159_RS14710	pilC	1714695..1714823 (+)	129	WP_002254125.1	hypothetical protein	Machinery gene
AN159_RS09065 (AN159_09095)	pilC	1714796..1717846 (+)	3051	Protein_1693	PilC family type IV pilus tip adhesin	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45189.45 Da
• Isoelectric Point: 4.5275

>NTDB_id=156613 AN159_RS09055 WP_002220091.1 1711997..1713262(+) (pilA) [Neisseria meningitidis strain 331401]
MFSFFRRKKKQETPALEEAQIQETAAKAESETDQVIENIKEDAESLAESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=156613 AN159_RS09055 WP_002220091.1 1711997..1713262(+) (pilA) [Neisseria meningitidis strain 331401]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAGTCCGAAACCGATCAAGTAATTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGACATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACTACGTCTATCGGTAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGACACCTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: X5EMG2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	93.824	100	0.938