Detailed information NTG0156553

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FORC27_RS14380
• Genome accession: NZ_CP012692
• Coordinates: 2801585..2802472 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain FORC_027
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2796585..2807472

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC27_RS14345	-	2796604..2796696 (+)	93	WP_010956583.1	hypothetical protein	-
FORC27_RS14350 (FORC27_2684)	-	2796804..2797301 (-)	498	WP_001065268.1	glutathione peroxidase	-
FORC27_RS14355	-	2797311..2797571 (-)	261	WP_001791974.1	hypothetical protein	-
FORC27_RS15690	-	2797953..2798066 (-)	114	Protein_2748	hypothetical protein	-
FORC27_RS14370 (FORC27_2685)	-	2798725..2800725 (-)	2001	WP_000776751.1	ABC transporter permease	-
FORC27_RS14375 (FORC27_2686)	-	2800722..2801477 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FORC27_RS14380 (FORC27_2687)	braS	2801585..2802472 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FORC27_RS14385 (FORC27_2688)	braR	2802483..2803148 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FORC27_RS14390 (FORC27_2689)	-	2803174..2803374 (-)	201	WP_000604730.1	hypothetical protein	-
FORC27_RS14400 (FORC27_2690)	-	2803572..2804996 (+)	1425	WP_000953755.1	alkaline phosphatase	-
FORC27_RS16175 (FORC27_2691)	-	2805056..2805157 (-)	102	WP_000731976.1	SE2200 family small protein	-
FORC27_RS14410 (FORC27_2692)	-	2805279..2805734 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FORC27_RS14415 (FORC27_2693)	-	2805979..2806740 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=156553 FORC27_RS14380 WP_000143425.1 2801585..2802472(-) (braS) [Staphylococcus aureus strain FORC_027]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=156553 FORC27_RS14380 WP_000143425.1 2801585..2802472(-) (braS) [Staphylococcus aureus strain FORC_027]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1