Detailed information NTG0156240

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LLUL8_RS07815
• Genome accession: NZ_CP015908
• Coordinates: 1543921..1546524 (-)
• Length: 867 a.a.
• NCBI ID: WP_003130040.1
• Uniprot ID: Q9CFF3
• Organism: Lactococcus lactis subsp. lactis strain UL8
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1538921..1551524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUL8_RS07795 (LLUL8_1526)	-	1539803..1540333 (+)	531	WP_003130052.1	TetR/AcrR family transcriptional regulator	-
LLUL8_RS07800 (LLUL8_1527)	-	1540384..1541973 (-)	1590	WP_010906017.1	ABC transporter ATP-binding protein	-
LLUL8_RS07805 (LLUL8_1528)	purN	1542140..1542688 (-)	549	WP_003130044.1	phosphoribosylglycinamide formyltransferase	-
LLUL8_RS07810 (LLUL8_1529)	purM	1542716..1543738 (-)	1023	WP_003130042.1	phosphoribosylformylglycinamidine cyclo-ligase	-
LLUL8_RS07815 (LLUL8_1530)	clpC	1543921..1546524 (-)	2604	WP_003130040.1	ATP-dependent chaperone ClpB	Regulator
LLUL8_RS07820 (LLUL8_1531)	-	1546758..1548098 (+)	1341	WP_003130038.1	hypothetical protein	-
LLUL8_RS07825 (LLUL8_1532)	-	1548131..1548754 (-)	624	WP_003130037.1	NAD-dependent epimerase/dehydratase family protein	-
LLUL8_RS07830 (LLUL8_1533)	purF	1548864..1550363 (-)	1500	WP_003130036.1	amidophosphoribosyltransferase	-
LLUL8_RS07835	-	1550478..1551322 (-)	845	Protein_1511	oxidoreductase	-

Sequence

Protein

• Length: 867 a.a.
• Molecular weight: 97335.08 Da
• Isoelectric Point: 4.8188

>NTDB_id=156240 LLUL8_RS07815 WP_003130040.1 1543921..1546524(-) (clpC) [Lactococcus lactis subsp. lactis strain UL8]
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDYTNLIEKEIDKINSVEGSNITY
GQNLSPDLFQIFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTSYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETY
KALEKYGVDLVAQVKSGKQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
SLDMGALIAGAKYRGEFEERLKAVLNEVKKSDGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDE
YRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLVDEAS
ATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQITEVVGRMTGIPITKLVEGERE
KLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEY
MEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIIVKMTSQLSHRLEEMDVQLEL
SEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVTLVENKIDFDIQTIAE

Nucleotide

• Length: 2604 bp

>NTDB_id=156240 LLUL8_RS07815 WP_003130040.1 1543921..1546524(-) (clpC) [Lactococcus lactis subsp. lactis strain UL8]
ATGGACATCGAAAAAATGACAACAACGATGCAAGAAGCACTTGGTTCAGCGCAACAAATTGCGCAAGTTCGTCATCACCA
AGTGATTGAAGTTCCACATTTATGGCGAATTTTTGTTCAACCTAATAGTTTTGGGGCGAACTTTTATAAAGATTTAGGGA
TTGACCTAGATGACTATACAAATTTAATTGAAAAAGAAATTGACAAAATTAATTCAGTAGAAGGTTCAAATATTACTTAT
GGTCAAAACCTAAGTCCAGATTTGTTCCAAATATTTACTGAAGCAGACAAAATTGCGCAAAAAATGGGCGATGAATACTT
ATCAACTGAGATTATTCTCCTTGCCCTCTTTGAATTAAAACAAAATCCATTGACCAGTTATTTGGTTAGCCATGGACTAA
CAAAAGCAAAAGCGCAAGCTGCAATTGAAAAATTACGCGGAGGTGATAAAGTGACCAGTCAAAATGCAGAAGAAACATAC
AAAGCACTTGAAAAATATGGGGTAGATCTCGTTGCTCAAGTTAAATCAGGTAAACAAGATCCTGTCATTGGACGTGATGA
AGAAATTCGTGATGTCATTCGAGTGCTTTCTCGTAAAACAAAAAATAACCCCGTTCTTATTGGTGAACCTGGGGTTGGTA
AAACAGCCATTGTTGAAGGATTGGCACAAAGGATTGTCAGAAAAGACGTTCCTGAAAATCTGAAAGATAAAACAATCTTT
TCACTTGATATGGGTGCCCTGATTGCAGGAGCGAAATATCGTGGTGAATTTGAAGAACGTTTGAAAGCAGTCCTTAATGA
AGTGAAAAAATCAGATGGACAAATTATCCTCTTTATTGATGAACTTCATACGATTGTTGGTGCAGGTAAAACAGAAGGTT
CAATGGACGCTGGGAACCTTTTAAAACCAATGCTTGCACGTGGTGAACTCCATTTGATTGGGGCAACTACCTTGGATGAA
TATCGTAAATACATGGAAACAGATAAAGCACTTGAACGTCGTTTCCAAAAGGTATTGGTTACTGAACCTACTGTTGAAGA
TACAATTTCAATCTTGCGTGGTCTAAAAGAACGTTTTGAAATTCACCATGGAGTGACCATTCATGATAATGCTTTAGTCG
CAGCAGCAACCCTTTCAAATCGTTATATTACTGACCGATTTTTACCAGATAAAGCCATTGACTTGGTTGATGAAGCCAGT
GCAACAATTCGTGTAGAAATGAATTCACTCCCAACTGAACTTGACCAAGCTAATCGTCGCTTGATGCAATTAGAAATTGA
AGAAGCGGCCCTCAAAAAAGAACGAGATGATGCTTCTAAGAAACGTCTTGAAATTATACGTGGTGAAATTGCTGAACTTC
GAGAAGAAAATAATCAACTCAAAGCTCAATGGGAAGCTGAGAAAAAAGAAGTGGGCAATATTTCTGAAAAACGAAATGAA
TTAGAACATGCTCGCCACGAATTGGAAGAAGCTCAAAATGAAGGAAACTTAGAAAAAGCAGCAGCCCTTCGTTATGGTAA
AATTCCTGAAATTGAAAAAGAACTCAAAGCTATTGAAGAAAAAGCAAAATCAGATGATTTATCCTTAGTTCAAGAATCAG
TCACTGAAGAACAAATCACTGAAGTTGTTGGACGCATGACAGGTATTCCAATTACCAAATTGGTTGAAGGTGAACGTGAA
AAATTACTTCACTTGCCAGAAACACTGCATCAAAGGGTCGTTGGACAAGATGAAGCTGTTGAAGCCGTATCTGATGCCAT
TATTCGTGCGCGTGCAGGAATTCAAGACCCTAATCGTCCACTTGGCTCATTCCTCTTCCTCGGTCCAACTGGGGTAGGTA
AGACCGAACTCGCGAAAGCTTTGGCTGAAAATCTCTTTGATTCAGAAGAACATATGGTTCGGATTGACATGAGTGAATAT
ATGGAAAAACACTCAGTTTCTCGGTTAGTCGGAGCACCTCCAGGATATGTCGGTTACGATGAAGGAGGCCAATTGACTGA
AGCTGTTCGTCGTAATCCTTATACAATCATCTTGCTTGATGAAATCGAAAAAGCACATCCAGATGTCTTCAATATCTTGT
TGCAAGTTTTGGATGACGGCCGTTTGACTGACTCTAAAGGTGTTCTCGTTGACTTTAAGAACACAGTGTTGATTATGACT
TCAAATGTCGGTTCTCAATATTTGCTTGATAATGTTGGAGAAAATGGTGAAATTTCGGAAGAAACAACTGAAAACGTGAT
GTCTCAACTTCGGGCACATTTCAAACCAGAATTTCTAAATCGAATTGATGATACCATTCTTTTCAAACCATTGGCACTTG
AGGATATTAAGAATATTATCGTTAAAATGACTAGCCAACTTTCACATCGTCTTGAAGAAATGGATGTTCAACTTGAGTTG
AGTGAAGAAGTAAAAGTTTGGATTGCCGAAAATGCTTATGAACCAGCTTATGGTGCACGTCCACTCAAACGTTATTTGAC
AAAAGTCATCGAAAATCCATTAGCTAAGCTGATTATCGGAGGAAAAATTCCACCAAAATCAAAAGTTATTGTAACGCTTG
TAGAAAACAAGATTGACTTTGATATTCAAACGATTGCTGAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (599-764)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (771-851)

• AAA lid domain (AAA_lid_9) (344-444)

• ATPase family associated with various cellular activities (AAA) (AAA) (205-339)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-67)

3D structure

• AlphaFold DB: Q9CFF3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.444	100	0.46
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.935	100	0.414