Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   RN80_RS07550 Genome accession   NZ_CP012646
Coordinates   1538957..1541215 (+) Length   752 a.a.
NCBI ID   WP_049515692.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1533957..1546215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS07515 (RN80_07530) - 1533958..1534143 (+) 186 WP_060628518.1 hypothetical protein -
  RN80_RS07520 (RN80_07535) - 1534167..1535018 (-) 852 WP_060628519.1 NAD(P)H-hydrate dehydratase -
  RN80_RS07525 (RN80_07540) - 1535076..1535849 (-) 774 WP_060628520.1 HAD hydrolase family protein -
  RN80_RS07530 (RN80_07545) - 1535854..1536711 (-) 858 WP_060628521.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  RN80_RS07535 (RN80_07550) - 1536889..1537623 (-) 735 WP_000140957.1 amino acid ABC transporter ATP-binding protein -
  RN80_RS07540 (RN80_07555) - 1537623..1538306 (-) 684 WP_001011642.1 amino acid ABC transporter permease -
  RN80_RS07545 (RN80_07560) - 1538497..1538727 (+) 231 WP_049515694.1 DUF1797 family protein -
  RN80_RS07550 (RN80_07565) clpE 1538957..1541215 (+) 2259 WP_049515692.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  RN80_RS07555 (RN80_07570) - 1541345..1541797 (+) 453 WP_060628522.1 NUDIX hydrolase -
  RN80_RS07560 (RN80_07575) - 1541962..1542261 (+) 300 WP_000767189.1 DUF1827 family protein -
  RN80_RS07565 (RN80_07580) - 1542397..1543029 (+) 633 WP_060628523.1 GNAT family N-acetyltransferase -
  RN80_RS07570 (RN80_07585) ezrA 1543081..1544808 (-) 1728 WP_060628524.1 septation ring formation regulator EzrA -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83790.25 Da        Isoelectric Point: 5.3727

>NTDB_id=156032 RN80_RS07550 WP_049515692.1 1538957..1541215(+) (clpE) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSNNTPPTPP
TQSGGGYGGNGGYGSQNRGPAQTPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVQYTDAA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
SEKDLKAVMTSKGKIQIKSAKKSEVKTSEKEV

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=156032 RN80_RS07550 WP_049515692.1 1538957..1541215(+) (clpE) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGCTTTGTCAAAACTGTAAAATCAACGACTCAACAATTCATCTTTACACCAATCTCAATGGAAAACAAAAACAAATTGA
CCTCTGTCAAAACTGCTACAAGATTATCAAGACTGATCCTAACAACAGTCTCTTTAAAGGTATGACGGATTTGAACAATC
GTGACTTTGATCCTTTCGGCGATTTCTTCAACGACCTAAACAATTTCAGACCTTCTAACAATACTCCTCCAACTCCCCCA
ACCCAATCAGGTGGAGGCTACGGTGGAAACGGCGGTTATGGCTCCCAAAATCGTGGACCTGCCCAAACTCCGCCTCCTAG
CCAAGAAAAAGGCCTGCTAGAAGAATTTGGTATCAATGTAACTGAGATTGCTCGTCGTGGCGATATTGACCCCGTTATTG
GACGCGACGATGAGATTATCCGTGTCATCGAGATTCTCAATCGTAGAACCAAGAATAATCCTGTTCTTATCGGTGAACCT
GGTGTCGGAAAAACTGCCGTTGTCGAAGGTCTAGCTCAGAAAATTGTTGATGGCGATGTTCCACATAAACTCCAAGGCAA
ACAAGTCATCCGTTTGGATGTAGTTAGCTTAGTTCAAGGAACGGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAGGATATTATCCTCTTTATCGATGAAATCCATGAAATTGTTGGTGCGGGGTCTGCG
GGCGATGGCAATATGGACGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGGGAACTGCAACTGGTCGGTGCCACTAC
CCTCAATGAATACCGTATCATTGAAAAAGATGCTGCCCTAGAGCGTCGTATGCAACCTGTTAAGGTCGATGAACCAACCG
TAGAAGAAACAATCACTATCCTCAAAGGAATTCAAAAGAAATACGAAGACTACCACCACGTTCAATATACTGATGCTGCA
ATTGAAGCAGCTGCAACTCTTTCCAATCGCTACATCCAAGATCGCTTCTTACCTGACAAGGCCATTGACCTCCTAGATGA
AGCAGGTTCTAAGATGAACTTAACCTTGAATTTTGTAGATCCTAAAGTGATTGATCAGCGCTTGATTGAAGCTGAAAATC
TCAAATCTCAAGCTACACGAGAGGAAGATTTTGAGAAGGCTGCCTATTTCCGCGACCAGATTGCCAAGTATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAAGATACTCCTATCATCAGTGAGAAAACCATTGAGCACATTATCGAGCAGAAAACCAA
CATTCCTGTTGGCGATTTGAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAGGATCTCAAGTCTCATGTTATTG
GACAAGACGATGCTGTCGATAAGATTGCCAAGGCTATTCGCCGTAATCGTGTCGGACTTGGGACCCCTAATCGTCCAATT
GGAAGTTTCCTCTTTGTTGGACCAACTGGTGTCGGTAAGACAGAACTTTCCAAACAACTAGCCATTGAACTTTTTGGTTC
TGCTGACAGCATGATTCGCTTTGACATGAGTGAATACATGGAAAAACATAGCGTTGCTAAGTTGGTCGGTGCCCCTCCAG
GTTATGTTGGCTATGATGAGGCTGGGCAATTAACTGAAAAAGTCCGCCGTAATCCATATTCTCTTATTCTCTTGGATGAA
GTAGAGAAAGCCCATCCAGATGTTATGCATATGTTCCTCCAGGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACG
TACCGTTAGCTTCAAGGATGCCATCATTATCATGACCTCAAATGCAGGTACAGGTAAGGCCGAAGCCAGCGTTGGATTTG
GTGCTGCTAGAGAAGGACGTACCAATTCTGTTCTCGGTGAACTCGGTAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGTATTATCGAATTTAAGGCTCTCAGCAAGGATAACCTCCTTCAGATTGTCGAGCTTATGCTAGCAGATGTTAACAA
ACGTCTTTCAAGTAACAACATTCATTTAGATGTAACTGACAAGGTCAAGGAAAAATTAGTTGACCTCGGTTATGATCCAA
AAATGGGGGCACGCCCACTTCGTCGTACTATTCAAGACTATATTGAGGACGCAATCACTGACTACTACCTTGAAAATCCA
AGCGAAAAAGACCTCAAGGCAGTTATGACCAGCAAGGGCAAGATTCAAATTAAGTCTGCCAAAAAATCTGAAGTAAAAAC
TTCTGAAAAAGAAGTATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(155-274)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(649-723)

AAA lid domain (AAA_lid_9)

(293-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

98.269

99.867

0.981
  clpE Streptococcus pneumoniae D39

98.269

99.867

0.981
  clpE Streptococcus pneumoniae R6

98.269

99.867

0.981
  clpE Streptococcus pneumoniae TIGR4

98.136

99.867

0.98
  clpE Streptococcus mutans UA159

83.467

99.734

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

75.626

100

0.763
  clpC Bacillus subtilis subsp. subtilis str. 168

50.43

92.819

0.468
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.847

83.378

0.399
  clpC Streptococcus pneumoniae TIGR4

47.293

83.511

0.395
  clpC Streptococcus pneumoniae Rx1

46.91

83.91

0.394
  clpC Streptococcus pneumoniae D39

46.91

83.91

0.394
  clpC Streptococcus mutans UA159

46.89

83.378

0.391
  clpC Streptococcus thermophilus LMD-9

46.795

82.979

0.388
  clpC Streptococcus thermophilus LMG 18311

46.4

83.112

0.386

Multiple sequence alignment