Detailed information NTG0155688

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LL275_RS08060
• Genome accession: NZ_CP015897
• Coordinates: 1625206..1627809 (-)
• Length: 867 a.a.
• NCBI ID: WP_003130040.1
• Uniprot ID: Q9CFF3
• Organism: Lactococcus lactis subsp. lactis strain 275
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1620206..1632809

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL275_RS08040 (LL275_1551)	-	1621089..1621619 (+)	531	WP_003130052.1	TetR/AcrR family transcriptional regulator	-
LL275_RS14700 (LL275_1552)	-	1621670..1621858 (-)	189	WP_003130050.1	hypothetical protein	-
LL275_RS14705 (LL275_1553)	-	1621886..1622530 (-)	645	WP_232626159.1	ABC transporter ATP-binding protein	-
LL275_RS14710 (LL275_1554)	-	1622539..1623258 (-)	720	WP_003130046.1	ABC transporter transmembrane domain-containing protein	-
LL275_RS08050 (LL275_1555)	purN	1623425..1623973 (-)	549	WP_003130044.1	phosphoribosylglycinamide formyltransferase	-
LL275_RS08055 (LL275_1556)	purM	1624001..1625023 (-)	1023	WP_003130042.1	phosphoribosylformylglycinamidine cyclo-ligase	-
LL275_RS08060 (LL275_1557)	clpC	1625206..1627809 (-)	2604	WP_003130040.1	ATP-dependent chaperone ClpB	Regulator
LL275_RS08065 (LL275_1558)	-	1628043..1629383 (+)	1341	WP_003130038.1	hypothetical protein	-
LL275_RS08070 (LL275_1559)	-	1629416..1630039 (-)	624	WP_003130037.1	NAD-dependent epimerase/dehydratase family protein	-
LL275_RS08075 (LL275_1560)	purF	1630149..1631648 (-)	1500	WP_003130036.1	amidophosphoribosyltransferase	-
LL275_RS08080 (LL275_1561)	-	1631763..1632607 (-)	845	Protein_1551	oxidoreductase	-

Sequence

Protein

• Length: 867 a.a.
• Molecular weight: 97335.08 Da
• Isoelectric Point: 4.8188

>NTDB_id=155688 LL275_RS08060 WP_003130040.1 1625206..1627809(-) (clpC) [Lactococcus lactis subsp. lactis strain 275]
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDYTNLIEKEIDKINSVEGSNITY
GQNLSPDLFQIFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTSYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETY
KALEKYGVDLVAQVKSGKQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
SLDMGALIAGAKYRGEFEERLKAVLNEVKKSDGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDE
YRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLVDEAS
ATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQITEVVGRMTGIPITKLVEGERE
KLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEY
MEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIIVKMTSQLSHRLEEMDVQLEL
SEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVTLVENKIDFDIQTIAE

Nucleotide

• Length: 2604 bp

>NTDB_id=155688 LL275_RS08060 WP_003130040.1 1625206..1627809(-) (clpC) [Lactococcus lactis subsp. lactis strain 275]
ATGGACATCGAAAAAATGACAACAACGATGCAAGAAGCACTTGGTTCAGCGCAACAAATTGCGCAAGTTCGTCATCACCA
AGTGATTGAAGTTCCACATTTATGGCGAATTTTTGTTCAACCTAATAGTTTTGGGGCGAACTTTTATAAAGATTTAGGGA
TTGACCTAGATGACTATACAAATTTAATTGAAAAAGAAATTGACAAAATTAATTCAGTAGAAGGTTCAAATATTACTTAT
GGTCAAAACCTAAGTCCAGATTTGTTCCAAATATTTACTGAAGCAGACAAAATTGCGCAAAAAATGGGCGATGAATACTT
ATCAACTGAGATTATTCTCCTTGCCCTCTTTGAATTAAAACAAAATCCATTGACCAGTTATTTGGTTAGCCATGGACTAA
CAAAAGCAAAAGCGCAAGCTGCAATTGAAAAATTACGCGGAGGTGATAAAGTGACCAGTCAAAATGCAGAAGAAACATAC
AAAGCACTTGAAAAATATGGGGTAGATCTCGTTGCTCAAGTTAAATCAGGTAAACAAGATCCTGTCATTGGACGTGATGA
AGAAATTCGTGATGTCATTCGAGTGCTTTCTCGTAAAACAAAAAATAACCCCGTTCTTATTGGTGAACCTGGGGTTGGTA
AAACAGCCATTGTTGAAGGATTGGCACAAAGGATTGTCAGAAAAGACGTTCCTGAAAATCTGAAAGATAAAACAATCTTT
TCACTTGATATGGGTGCCCTGATTGCAGGAGCGAAATATCGTGGTGAATTTGAAGAACGTTTGAAAGCAGTCCTTAATGA
AGTGAAAAAATCAGATGGACAAATTATCCTCTTTATTGATGAACTTCATACGATTGTTGGTGCAGGTAAAACAGAAGGTT
CAATGGACGCTGGGAACCTTTTAAAACCAATGCTTGCACGTGGTGAACTCCATTTGATTGGGGCAACTACCTTGGATGAA
TATCGTAAATACATGGAAACAGATAAAGCACTTGAACGTCGTTTCCAAAAGGTATTGGTTACTGAACCTACTGTTGAAGA
TACAATTTCAATCTTGCGTGGTCTAAAAGAACGTTTTGAAATTCACCATGGAGTGACCATTCATGATAATGCTTTAGTCG
CAGCAGCAACCCTTTCAAATCGTTATATTACTGACCGATTTTTACCAGATAAAGCCATTGACTTGGTTGATGAAGCCAGT
GCAACAATTCGTGTAGAAATGAATTCACTCCCAACTGAACTTGACCAAGCTAATCGTCGCTTGATGCAATTAGAAATTGA
AGAAGCGGCCCTCAAAAAAGAACGAGATGATGCTTCTAAGAAACGTCTTGAAATTATACGTGGTGAAATTGCTGAACTTC
GAGAAGAAAATAATCAACTCAAAGCTCAATGGGAAGCTGAGAAAAAAGAAGTGGGCAATATTTCTGAAAAACGAAATGAA
TTAGAACATGCTCGCCACGAATTGGAAGAAGCTCAAAATGAAGGAAACTTAGAAAAAGCAGCAGCCCTTCGTTATGGTAA
AATTCCTGAAATTGAAAAAGAACTCAAAGCTATTGAAGAAAAAGCAAAATCAGATGATTTATCCTTAGTTCAAGAATCAG
TCACTGAAGAACAAATCACTGAAGTTGTTGGACGCATGACAGGTATTCCAATTACCAAATTGGTTGAAGGTGAACGTGAA
AAATTACTTCACTTGCCAGAAACACTGCATCAAAGGGTCGTTGGACAAGATGAAGCTGTTGAAGCCGTATCTGATGCCAT
TATTCGTGCGCGTGCAGGAATTCAAGACCCTAATCGTCCACTTGGCTCATTCCTCTTCCTCGGTCCAACTGGGGTAGGTA
AGACCGAACTCGCGAAAGCTTTGGCTGAAAATCTCTTTGATTCAGAAGAACATATGGTTCGGATTGACATGAGTGAATAT
ATGGAAAAACACTCAGTTTCTCGGTTAGTCGGAGCACCTCCAGGATATGTCGGTTACGATGAAGGAGGCCAATTGACTGA
AGCTGTTCGTCGTAATCCTTATACAATCATCTTGCTTGATGAAATCGAAAAAGCACATCCAGATGTCTTCAATATCTTGT
TGCAAGTTTTGGATGACGGCCGTTTGACTGACTCTAAAGGTGTTCTCGTTGACTTTAAGAACACAGTGTTGATTATGACT
TCAAATGTCGGTTCTCAATATTTGCTTGATAATGTTGGAGAAAATGGTGAAATTTCGGAAGAAACAACTGAAAACGTGAT
GTCTCAACTTCGGGCACATTTCAAACCAGAATTTCTAAATCGAATTGATGATACCATTCTTTTCAAACCATTGGCACTTG
AGGATATTAAGAATATTATCGTTAAAATGACTAGCCAACTTTCACATCGTCTTGAAGAAATGGATGTTCAACTTGAGTTG
AGTGAAGAAGTAAAAGTTTGGATTGCCGAAAATGCTTATGAACCAGCTTATGGTGCACGTCCACTCAAACGTTATTTGAC
AAAAGTCATCGAAAATCCATTAGCTAAGCTGATTATCGGAGGAAAAATTCCACCAAAATCAAAAGTTATTGTAACGCTTG
TAGAAAACAAGATTGACTTTGATATTCAAACGATTGCTGAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (599-764)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (771-851)

• AAA lid domain (AAA_lid_9) (344-444)

• ATPase family associated with various cellular activities (AAA) (AAA) (205-339)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-67)

3D structure

• AlphaFold DB: Q9CFF3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.444	100	0.46
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.935	100	0.414