Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A7B19_RS16975 Genome accession   NZ_CP015726
Coordinates   4243372..4244001 (+) Length   209 a.a.
NCBI ID   WP_009717816.1    Uniprot ID   D9WQ56
Organism   Streptomyces sp. RTd22     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4238372..4249001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7B19_RS16955 - 4239266..4240822 (-) 1557 WP_234365188.1 PH domain-containing protein -
  A7B19_RS16960 - 4240819..4241319 (-) 501 WP_063732699.1 PH domain-containing protein -
  A7B19_RS16965 - 4241398..4241943 (-) 546 WP_009717818.1 hypothetical protein -
  A7B19_RS16970 - 4242135..4243379 (+) 1245 WP_063732698.1 sensor histidine kinase -
  A7B19_RS16975 vraR 4243372..4244001 (+) 630 WP_009717816.1 response regulator transcription factor Regulator
  A7B19_RS16980 - 4244024..4246033 (-) 2010 WP_234365642.1 helix-turn-helix transcriptional regulator -
  A7B19_RS52645 - 4245973..4246839 (-) 867 WP_234365643.1 ATP-binding protein -
  A7B19_RS16985 - 4246934..4247695 (-) 762 WP_009717814.1 thioesterase II family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 22007.47 Da        Isoelectric Point: 5.1121

>NTDB_id=154606 A7B19_RS16975 WP_009717816.1 4243372..4244001(+) (vraR) [Streptomyces sp. RTd22]
MADQEIRVLLADDHPVVREGLSAMLESADGITVVGQAGSGEEAVVQAMALRPDIILLDLRMGGMDGVEATTQILRKAPAC
KVVIVTTYEDDSDILRAVEAGAAGYLLKGSSRQELIGAVQTAARGETVLTPSLAGKLLRTRVAEPSPLSGRECEVLRLVG
QGLTNAEIGAKLFVAEATVKTHLLRSFKKLGVSDRTAAVMTAMERGLLS

Nucleotide


Download         Length: 630 bp        

>NTDB_id=154606 A7B19_RS16975 WP_009717816.1 4243372..4244001(+) (vraR) [Streptomyces sp. RTd22]
ATGGCTGACCAGGAGATCCGGGTCCTGCTCGCGGATGACCATCCCGTGGTGCGGGAGGGCCTGAGCGCCATGCTGGAGTC
CGCCGACGGCATCACCGTCGTCGGACAGGCCGGTTCGGGCGAGGAGGCGGTCGTCCAGGCGATGGCGCTGCGGCCGGACA
TCATCCTGCTGGACCTGCGCATGGGCGGGATGGACGGGGTCGAGGCCACCACGCAGATCCTGCGGAAGGCGCCCGCCTGC
AAGGTCGTCATCGTGACCACGTACGAGGACGACTCCGACATCCTGCGCGCGGTCGAGGCGGGCGCCGCGGGCTATCTGCT
GAAGGGCAGTTCACGCCAGGAGCTGATCGGCGCCGTACAGACCGCGGCGCGCGGCGAGACGGTGCTCACCCCGTCCCTCG
CGGGCAAGCTGCTGCGTACCCGGGTGGCCGAGCCGTCCCCGCTGTCCGGCCGTGAGTGCGAGGTGCTGCGGCTGGTCGGC
CAGGGGCTGACCAACGCGGAGATCGGCGCCAAGCTGTTCGTGGCCGAGGCCACGGTGAAGACACATCTGCTGCGTTCGTT
CAAGAAGCTCGGCGTCTCCGACCGCACGGCGGCCGTGATGACGGCCATGGAGCGCGGACTGCTGTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D9WQ56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.262

98.565

0.407

Multiple sequence alignment