Detailed information NTG0154591

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A7B19_RS08120
• Genome accession: NZ_CP015726
• Coordinates: 2159398..2162061 (-)
• Length: 887 a.a.
• NCBI ID: WP_063726491.1
• Uniprot ID: -
• Organism: Streptomyces sp. RTd22
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2154398..2167061

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7B19_RS08090	-	2155330..2155779 (+)	450	WP_039939616.1	DUF1931 family protein	-
A7B19_RS08095	-	2155829..2156263 (-)	435	WP_234364843.1	DUF2267 domain-containing protein	-
A7B19_RS08100	-	2156338..2156832 (-)	495	WP_039939614.1	Hsp20/alpha crystallin family protein	-
A7B19_RS08105	-	2156829..2158658 (-)	1830	WP_063726493.1	FAD-dependent oxidoreductase	-
A7B19_RS08110	-	2158658..2158921 (-)	264	WP_009719502.1	UBP-type zinc finger domain-containing protein	-
A7B19_RS08115	trxA	2158927..2159391 (-)	465	WP_063726492.1	thioredoxin	-
A7B19_RS08120	clpC	2159398..2162061 (-)	2664	WP_063726491.1	ATP-dependent chaperone ClpB	Regulator
A7B19_RS08125	-	2162052..2162420 (-)	369	WP_009719499.1	chaperone modulator CbpM	-
A7B19_RS08130	-	2162417..2163385 (-)	969	WP_063726490.1	DnaJ C-terminal domain-containing protein	-
A7B19_RS08135	grpE	2163392..2163985 (-)	594	WP_063726489.1	nucleotide exchange factor GrpE	-
A7B19_RS08140	dnaK	2163996..2165912 (-)	1917	WP_063726488.1	molecular chaperone DnaK	-

Sequence

Protein

• Length: 887 a.a.
• Molecular weight: 99041.59 Da
• Isoelectric Point: 5.0974

>NTDB_id=154591 A7B19_RS08120 WP_063726491.1 2159398..2162061(-) (clpC) [Streptomyces sp. RTd22]
MDMNRLTEKSQEALQNAQTTAMRFGHTEVDGEHLLFALLDQPEGLIPRLVTQVGADPEAMRSMLEAELARKPKVTGPGAA
PGQVFVTQRLSQLLDTAEQEAKRLKDEYVSVEHLVLAFTDEGSGTAAGRVLKEHGITKDAFLHALTQVRGSQRVTSANPE
VAYEALEKYGRDLVLEARSGKLDPVIGRDAEIRRVTQILSRKSKNNPVLIGDPGVGKTAIVEGLAQRIVRGDVPEGLRDK
TVFALDMGSLVAGAKYRGEFEERLKAVLAEVKAAQGRILLFIDELHTVVGAGAAEGAMDAGNMLKPMLARGELHMIGATT
LDEYRKHIEKDAALERRFQTVMVDEPGVEDTISILRGLRERLEVFHGVKIQDTALVAAATMSHRYISDRFLPDKAIDLVD
EACARLRTEIDSMPAELDEITRRVTRLEIEEAALSKETDPASRQRLEELRKELADLRAEADAKRAQWEAERQSIRRVQEL
RRELEEVRREAEEAERNYDLNRAAELRYGKLQELERKLAAEEEQLAAKQGEHRLLREVVTEDEISDIVSAWTGIPVSRLK
EGEREKLLRLDEILQERVIGQDEAVKLVSDAIIRARSGIRDPRRPIGSFIFLGPTGVGKTELAKTLAAALFDTEENMIRL
DMSEYQERHTVSRLVGAPPGYVGYEEGGQLTEAVRRKPYSVVLLDEIEKAHTDVFNTLLQVLDDGRITDAQGRLVDFRNT
VIIMTSNIGSVHLLDGVTSEGELKPDARSLVMSELRGHFRPEFLNRVDDIVLFKPLGEPQIERIVDLQFDELRKRLAERL
IAVELTPEARKVIAHEGYDPVYGARPLRRFISHEVETLIGRALLKGDVQEGTTIKVDGRHGELVVTYEQPSGEHVEERAR
QEAGGAA

Nucleotide

• Length: 2664 bp

>NTDB_id=154591 A7B19_RS08120 WP_063726491.1 2159398..2162061(-) (clpC) [Streptomyces sp. RTd22]
ATGGACATGAACCGTCTCACCGAGAAGTCCCAGGAAGCCCTCCAGAACGCTCAGACCACTGCGATGCGGTTCGGGCACAC
CGAAGTCGACGGCGAGCACCTGCTGTTCGCACTCCTCGACCAGCCGGAGGGTCTGATCCCGCGACTGGTCACCCAGGTGG
GCGCCGATCCCGAGGCGATGCGCTCGATGCTGGAGGCCGAGCTGGCGCGCAAGCCCAAGGTCACCGGCCCCGGCGCCGCC
CCCGGACAGGTCTTCGTCACCCAGCGCCTCTCCCAGTTGCTGGACACCGCCGAGCAGGAGGCCAAGCGGCTCAAGGACGA
GTACGTTTCGGTCGAACACCTCGTCCTCGCGTTCACCGACGAGGGGTCCGGCACCGCGGCCGGACGCGTGCTCAAGGAGC
ACGGCATCACCAAGGACGCGTTCCTGCACGCCCTCACGCAGGTCCGCGGCAGCCAGCGGGTCACCTCCGCCAACCCGGAA
GTGGCGTACGAGGCGCTGGAGAAGTACGGCCGCGATCTGGTCCTGGAGGCCCGCTCCGGCAAGCTGGACCCGGTCATCGG
CCGGGACGCCGAGATCCGCCGGGTGACCCAGATCCTCAGCCGCAAGTCGAAGAACAACCCGGTGCTCATCGGCGACCCCG
GTGTCGGCAAGACCGCCATCGTCGAGGGCCTGGCGCAGCGCATCGTACGCGGTGATGTGCCCGAAGGGCTGCGCGACAAG
ACCGTGTTCGCCCTCGACATGGGCTCCCTGGTGGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGGCTCAAGGCCGT
ACTTGCCGAGGTCAAGGCCGCCCAGGGCAGGATCCTGCTCTTCATCGACGAGCTGCACACCGTGGTCGGCGCCGGGGCGG
CCGAGGGCGCCATGGACGCGGGGAACATGCTCAAGCCGATGCTGGCCCGCGGTGAGCTGCACATGATCGGCGCGACCACC
CTCGACGAGTACCGCAAGCACATCGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGACGGTGATGGTGGACGAGCCCGG
CGTGGAGGACACCATCTCCATCCTGCGGGGCCTGCGCGAGCGGCTGGAGGTCTTCCACGGCGTCAAGATCCAGGACACCG
CCCTGGTCGCCGCCGCCACCATGAGCCACCGCTATATCAGCGACCGGTTCCTGCCCGACAAGGCCATCGACCTGGTCGAC
GAGGCTTGTGCCCGGCTGCGTACCGAGATCGACTCCATGCCCGCCGAGCTGGACGAGATCACCCGCCGGGTCACCCGGCT
GGAGATCGAGGAGGCCGCGCTCTCCAAGGAGACCGACCCGGCCAGCCGGCAGCGGCTGGAGGAACTGCGCAAGGAACTCG
CCGACCTGCGGGCCGAGGCCGACGCCAAGCGCGCCCAGTGGGAGGCCGAGCGGCAGTCCATCCGCCGGGTGCAGGAGCTG
CGCAGGGAACTGGAGGAGGTGCGCCGCGAGGCCGAGGAGGCCGAACGCAACTACGACCTCAACCGCGCCGCCGAACTGCG
CTACGGCAAGCTCCAGGAGCTGGAGCGCAAGCTGGCCGCCGAGGAGGAGCAGCTGGCCGCCAAGCAGGGCGAGCACCGGC
TGCTGCGCGAGGTCGTCACCGAGGACGAGATCAGCGACATCGTCTCCGCCTGGACCGGAATCCCGGTCTCCCGCCTCAAG
GAGGGCGAACGGGAGAAGCTGCTGCGCCTGGATGAGATCCTCCAGGAGCGGGTCATCGGCCAGGACGAGGCGGTCAAGCT
GGTCTCCGACGCCATCATCCGCGCCCGCTCGGGCATCCGGGACCCGCGCCGCCCGATCGGCTCGTTCATCTTCCTCGGCC
CCACCGGCGTCGGAAAGACCGAGCTGGCCAAGACGCTGGCCGCCGCGCTCTTCGACACCGAGGAGAACATGATCCGCCTG
GATATGAGCGAGTACCAGGAGCGGCACACCGTCAGCCGGCTGGTCGGCGCCCCGCCGGGGTACGTCGGCTACGAGGAGGG
CGGCCAGCTCACCGAGGCGGTGCGGCGCAAACCGTACTCGGTCGTGCTCCTGGACGAGATCGAGAAGGCGCACACCGACG
TCTTCAACACCCTGCTGCAGGTCCTCGACGACGGCCGGATCACCGACGCCCAGGGGCGGCTGGTGGACTTCCGCAACACC
GTGATCATCATGACCTCCAACATCGGCTCCGTGCACCTGCTGGACGGCGTCACCTCCGAGGGCGAGCTCAAGCCGGACGC
CCGGAGCCTGGTGATGAGCGAGCTGCGCGGGCACTTCCGCCCCGAGTTCCTCAACCGGGTCGATGACATCGTGCTGTTCA
AGCCGCTCGGCGAGCCCCAGATCGAGCGGATCGTGGATCTGCAGTTCGACGAGCTGCGCAAGCGCCTGGCCGAACGCCTG
ATCGCCGTCGAACTCACCCCGGAAGCCCGGAAGGTCATCGCCCACGAGGGCTACGACCCGGTCTACGGTGCCCGGCCGCT
GCGCCGCTTCATCTCCCACGAGGTCGAGACCCTCATCGGACGCGCCCTGCTGAAGGGCGACGTCCAGGAGGGCACCACGA
TCAAGGTCGACGGCCGGCACGGCGAACTGGTGGTCACCTACGAACAGCCGTCGGGCGAGCACGTCGAGGAACGAGCCCGG
CAGGAAGCCGGAGGGGCAGCGTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (208-340)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-150)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA lid domain (AAA_lid_9) (348-449)

• AAA domain (Cdc48 subfamily) (AAA_2) (604-770)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (776-856)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.029	98.647	0.444
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.237	98.422	0.406
clpC	Lactococcus lactis subsp. cremoris KW2	47.278	78.692	0.372