Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A7B19_RS06775 Genome accession   NZ_CP015726
Coordinates   1814944..1815606 (+) Length   220 a.a.
NCBI ID   WP_063726699.1    Uniprot ID   -
Organism   Streptomyces sp. RTd22     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1809944..1820606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7B19_RS06755 - 1811216..1811749 (-) 534 WP_234364869.1 EF-hand domain-containing protein -
  A7B19_RS06760 - 1811891..1812625 (-) 735 WP_063726702.1 ABC transporter permease -
  A7B19_RS06765 - 1812659..1813585 (-) 927 WP_063726701.1 ABC transporter ATP-binding protein -
  A7B19_RS06770 - 1813693..1814907 (+) 1215 WP_063726700.1 sensor histidine kinase -
  A7B19_RS06775 vraR 1814944..1815606 (+) 663 WP_063726699.1 response regulator transcription factor Regulator
  A7B19_RS06780 - 1815632..1816366 (-) 735 WP_063726698.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -
  A7B19_RS53820 - 1816439..1816747 (+) 309 WP_267895467.1 MFS transporter -
  A7B19_RS06785 - 1816735..1817967 (+) 1233 WP_267895468.1 MFS transporter -
  A7B19_RS50235 - 1817929..1818081 (-) 153 WP_154686034.1 hypothetical protein -
  A7B19_RS06790 - 1818078..1819280 (-) 1203 WP_199844160.1 MFS transporter -
  A7B19_RS54695 - 1819288..1819488 (-) 201 Protein_1430 MFS transporter -
  A7B19_RS06795 - 1819703..1820482 (+) 780 WP_234364868.1 Crp/Fnr family transcriptional regulator -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23228.70 Da        Isoelectric Point: 4.7367

>NTDB_id=154589 A7B19_RS06775 WP_063726699.1 1814944..1815606(+) (vraR) [Streptomyces sp. RTd22]
MLTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLMDGIEATRTVLRTVPDPPKII
VVTTFENDEYVYGALRAGADGFLLKRARPAEIVHAVRLVAEGDSLLFPAAVRQLAASYGEADGSAEGRAALERAALTERE
GDVLRLVARGLSNAEIAARLVVGTETVKSHVSSVLAKLGARDRTQAVIAAYESGFVSPGG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=154589 A7B19_RS06775 WP_063726699.1 1814944..1815606(+) (vraR) [Streptomyces sp. RTd22]
ATGCTCACCGTTCTCCTGGTCGACGACGAGCCTCTGGTGAGGGCGGGCCTGCGCGCCGTGCTGGAGGCGCAGCCGGACAT
CGAGGTGGTGGGCGAGGCGGCCGACGGCGCCGCCGTGATCCCCCTGGTGCGGCAACTGCGACCCGACGTCGTCGCCATGG
ACGTACGGATGCCCCTGATGGACGGCATCGAGGCCACCCGTACCGTCCTGCGCACGGTGCCGGACCCGCCGAAGATCATC
GTGGTGACGACCTTCGAGAACGACGAGTACGTGTACGGGGCGCTGCGCGCGGGCGCCGATGGGTTCCTGCTGAAGCGGGC
GCGCCCGGCGGAGATCGTGCACGCCGTGCGGCTGGTGGCCGAGGGCGACTCGCTGCTGTTCCCGGCGGCGGTGCGGCAGT
TGGCCGCCTCGTACGGTGAGGCCGACGGCAGCGCCGAGGGCCGGGCGGCCCTGGAGCGTGCCGCGCTGACCGAGCGGGAG
GGGGACGTGCTGCGGCTGGTGGCCCGCGGGCTGTCGAACGCGGAGATTGCGGCGCGTCTGGTGGTGGGCACCGAGACCGT
CAAGTCGCATGTGAGTTCCGTGCTGGCGAAGCTCGGCGCGCGGGACCGCACCCAGGCGGTCATCGCCGCGTACGAGTCCG
GCTTCGTGTCACCGGGCGGATGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.278

98.182

0.395
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.382

Multiple sequence alignment