Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   WUE2121_RS04355 Genome accession   NZ_CP012394
Coordinates   832224..832898 (+) Length   224 a.a.
NCBI ID   WP_063399723.1    Uniprot ID   A0AAC9CPR4
Organism   Neisseria meningitidis strain WUE2121     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 827224..837898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WUE2121_RS14995 - 827937..828044 (+) 108 Protein_818 IS5/IS1182 family transposase -
  WUE2121_RS04335 (WUE2121_0813) - 828089..828421 (+) 333 WP_002213854.1 hypothetical protein -
  WUE2121_RS04340 (WUE2121_0814) - 828752..829261 (+) 510 WP_063399725.1 isoprenylcysteine carboxyl methyltransferase family protein -
  WUE2121_RS04345 (WUE2121_0815) - 829759..830346 (-) 588 WP_002220670.1 superoxide dismutase -
  WUE2121_RS04350 (WUE2121_0816) dnaB 830509..831915 (+) 1407 WP_002220671.1 replicative DNA helicase -
  WUE2121_RS04355 (WUE2121_0817) pilH 832224..832898 (+) 675 WP_063399723.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  WUE2121_RS04360 (WUE2121_0818) pilV 832922..833545 (+) 624 WP_063399721.1 type IV pilus modification protein PilV Machinery gene
  WUE2121_RS04365 (WUE2121_0819) pilJ 833542..834483 (+) 942 WP_002235685.1 PilW family protein Machinery gene
  WUE2121_RS04370 (WUE2121_0820) pilK 834462..835058 (+) 597 WP_002236356.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  WUE2121_RS04375 (WUE2121_0821) pilL 835063..835560 (+) 498 WP_002235687.1 PilX family type IV pilin Machinery gene

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25204.91 Da        Isoelectric Point: 10.1641

>NTDB_id=154209 WUE2121_RS04355 WP_063399723.1 832224..832898(+) (pilH) [Neisseria meningitidis strain WUE2121]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGAPN
NRCDFSKKGRGMLAFGDKNGNKAYDGDAADVFLRRVVLNDTDDSRINYAFNHIAFGSSQPTADRVVWTFNQNGTFGYTKD
QHLTSKSSFFYSDGYIQIVLTDARAVLDADKKFRSAVVLIDSSGRVEVCPRGDRRTRRTMCQYK

Nucleotide


Download         Length: 675 bp        

>NTDB_id=154209 WUE2121_RS04355 WP_063399723.1 832224..832898(+) (pilH) [Neisseria meningitidis strain WUE2121]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGCCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGCGGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGCATATGACGGCGA
TGCGGCGGATGTTTTCCTCCGCAGAGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTATGCCTTCAACCATATCG
CTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAAGAC
CAGCATCTTACAAGCAAATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTT
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGCCCTAGGGGTGATC
GGCGTACTCGGCGTACTATGTGCCAGTATAAATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

89.302

95.982

0.857

Multiple sequence alignment