Detailed information NTG0154066

Bioinformatically predicted

Overview

• Name: tpc
• Type: Machinery gene
• Locus tag: DE8669_RS03795
• Genome accession: NZ_CP012391
• Coordinates: 730498..731496 (-)
• Length: 332 a.a.
• NCBI ID: WP_014582402.1
• Uniprot ID: A0A425B2J6
• Organism: Neisseria meningitidis strain DE8669
• Function: DNA processing; DNA transport into the cytoplasm (predicted from homology) DNA processing DNA binding and uptake

Genomic Context

Location: 725498..736496

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DE8669_RS03775 (DE8669_0709)	-	726876..727502 (-)	627	WP_014582401.1	phosphoribosylanthranilate isomerase	-
DE8669_RS03780 (DE8669_0710)	greB	727561..728052 (-)	492	WP_002214159.1	transcription elongation factor GreB	-
DE8669_RS03785 (DE8669_0711)	purF	728152..729696 (-)	1545	WP_002223939.1	amidophosphoribosyltransferase	-
DE8669_RS14975 (DE8669_0712)	-	729841..729972 (-)	132	WP_256824360.1	hypothetical protein	-
DE8669_RS03790 (DE8669_0713)	-	730008..730505 (-)	498	WP_002219589.1	CvpA family protein	-
DE8669_RS03795 (DE8669_0714)	tpc	730498..731496 (-)	999	WP_014582402.1	cell division protein FtsN	Machinery gene
DE8669_RS03800 (DE8669_0715)	folC	731509..732783 (-)	1275	WP_014582403.1	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	-
DE8669_RS03805 (DE8669_0716)	-	732815..733255 (-)	441	WP_002219586.1	protein YgfX	-
DE8669_RS03810 (DE8669_0717)	-	733260..733619 (-)	360	WP_002219585.1	hypothetical protein	-
DE8669_RS03815 (DE8669_0718)	-	733692..734420 (-)	729	WP_002219584.1	amino acid ABC transporter ATP-binding protein	-
DE8669_RS03820 (DE8669_0720)	rsmA	734593..735372 (-)	780	WP_002219583.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
DE8669_RS03825 (DE8669_0721)	-	735569..736258 (+)	690	WP_002219582.1	uracil-DNA glycosylase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 35582.96 Da
• Isoelectric Point: 10.1759

>NTDB_id=154066 DE8669_RS03795 WP_014582402.1 730498..731496(-) (tpc) [Neisseria meningitidis strain DE8669]
MSENKQNEVLSGYEQLKRRNRRRLVTASCLVAASCILLAAALSSGPAEQTAGETSGVENKAAGAAQTPALKSAADKPQDL
AGEDKPSAADSEISEPENVGAPLVLINERLEDSNIKGLEASEKLQQAETAKTAPKQAKQRAAEKVPATADSTDTVAFEKP
KRTAETKPQKAERTAKAKPKAKETKTAEKVADKPKTAAEKTKPDTAKSDSAVKEAKKADKAESKKTAEKDRSDGKKHETA
QKTDKADKTKTAEKEKSGKKAAIQAGYAEKERALSLQRKMKAAGIDSTITEIMTDNGKVYRVKSSNYKNARDAERDLNKL
RVHGIAGQVTNE

Nucleotide

• Length: 999 bp

>NTDB_id=154066 DE8669_RS03795 WP_014582402.1 730498..731496(-) (tpc) [Neisseria meningitidis strain DE8669]
ATGTCCGAAAACAAACAAAACGAAGTCCTGAGCGGTTACGAACAACTCAAACGGCGCAACCGCCGCCGCCTCGTAACGGC
AAGTTGCTTGGTTGCCGCCTCCTGCATCCTGCTGGCAGCCGCCCTCAGTTCCGGCCCTGCCGAACAGACTGCCGGCGAAA
CAAGCGGCGTAGAAAACAAAGCGGCAGGTGCGGCACAAACCCCTGCCTTGAAATCCGCCGCCGACAAACCGCAGGACTTG
GCAGGCGAAGACAAGCCTTCTGCCGCCGACAGCGAAATCAGCGAGCCTGAAAACGTAGGCGCGCCGCTGGTGCTGATTAA
CGAGCGCCTCGAAGACAGCAACATCAAAGGTTTGGAAGCATCCGAGAAACTGCAACAGGCAGAAACCGCCAAAACCGCAC
CGAAGCAGGCAAAACAACGCGCTGCCGAAAAAGTGCCGGCAACTGCCGACAGTACGGATACGGTAGCGTTTGAAAAACCG
AAACGCACTGCCGAAACAAAACCGCAAAAAGCGGAACGCACTGCCAAAGCCAAGCCCAAAGCCAAAGAAACCAAAACCGC
CGAAAAAGTTGCCGACAAACCGAAAACTGCCGCCGAAAAAACCAAACCGGATACGGCAAAATCCGACAGCGCGGTAAAAG
AAGCGAAAAAAGCCGACAAGGCTGAAAGCAAAAAAACAGCCGAAAAAGACCGTTCGGACGGCAAAAAACACGAAACGGCA
CAAAAAACCGACAAAGCGGACAAGACCAAAACCGCCGAGAAGGAAAAATCCGGTAAAAAAGCCGCCATTCAGGCAGGTTA
TGCCGAAAAAGAACGCGCCTTAAGCCTCCAGCGCAAAATGAAGGCGGCGGGTATCGATTCGACCATCACCGAAATTATGA
CCGACAACGGCAAAGTTTACCGCGTCAAATCAAGCAACTATAAAAACGCAAGGGATGCCGAACGCGATTTGAACAAATTG
CGCGTACACGGTATCGCCGGTCAGGTAACGAATGAATAG

Domains

Predicted by InterproScan.

• SPOR domain (SPOR) (259-330)

3D structure

• AlphaFold DB: A0A425B2J6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
tpc	Neisseria gonorrhoeae MS11	89.306	100	0.931