Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   A6E92_RS25790 Genome accession   NZ_CP015362
Coordinates   6051224..6054241 (+) Length   1005 a.a.
NCBI ID   WP_084996131.1    Uniprot ID   -
Organism   Streptomyces sp. S8     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6046224..6059241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6E92_RS25775 (A6E92_25330) - 6048442..6049461 (+) 1020 WP_084996128.1 TerC family protein -
  A6E92_RS25780 (A6E92_25335) - 6049648..6050304 (-) 657 WP_084996129.1 MBL fold metallo-hydrolase -
  A6E92_RS25785 (A6E92_25340) - 6050358..6051047 (-) 690 WP_084996130.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  A6E92_RS25790 (A6E92_25345) uvrA 6051224..6054241 (+) 3018 WP_084996131.1 excinuclease ABC subunit UvrA Machinery gene
  A6E92_RS25795 (A6E92_25350) - 6054477..6054905 (+) 429 WP_018488106.1 Rieske (2Fe-2S) protein -
  A6E92_RS25800 (A6E92_25355) - 6055099..6056025 (-) 927 WP_084996132.1 hypothetical protein -
  A6E92_RS25805 (A6E92_25360) - 6056253..6056864 (+) 612 WP_084996133.1 papain-like cysteine protease family protein -
  A6E92_RS33360 (A6E92_25365) - 6056869..6057801 (+) 933 WP_084996134.1 hypothetical protein -

Sequence

Protein


Download         Length: 1005 a.a.        Molecular weight: 110130.27 Da        Isoelectric Point: 7.8551

>NTDB_id=153472 A6E92_RS25790 WP_084996131.1 6051224..6054241(+) (uvrA) [Streptomyces sp. S8]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPIARQSPQAIVDKVLGLPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGVTIQLSEPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCAYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDEEKSLDEGAIHPWSHGHTK
EYFGRLIGALAKALGFRTDIPWAGLPQRAKKALLYGHKIQTEVRYRNRYGRERAYTTPAFEGAVQFVKRRHTEAESDSSR
ERFEGYMREVPCPTCEGSRLKPIVLAVTVMEKSIAEVSAMSISDCAEFLGRLKLNARDKKIAERVLKEVNERLKFLVDVG
LDYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVA
DWVVDIGPGAGEHGGKVVHSGSLKELLSNKESVTGQYLSGKRSIPTPDVRRPVDPERSLTVHGARENNLHDIDVSFPLGV
LTAVTGVSGSGKSTLVNDILYTHLARELNGAKSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLF
AETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEE
GLEFFEAVPAIARHLRTLNDVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLITVL
SGLVDKGNSVIVIEHNLDVIKTADWVIDMGPEGGNGGGMVVAEGTPEQVASVPASHTGKFLQGILDADRISEAAVPSGRG
AARRTAARKTTAAKKTAAPKKAATATKKAAATKATAKKATRARKA

Nucleotide


Download         Length: 3018 bp        

>NTDB_id=153472 A6E92_RS25790 WP_084996131.1 6051224..6054241(+) (uvrA) [Streptomyces sp. S8]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAACCTGAAGAACGTCTCGCTCGATCTCCCCCGTGACTCCCT
CATCGTCTTCACCGGGCTCTCCGGGTCGGGCAAGTCGTCCCTCGCGTTCGACACGATCTTCGCCGAGGGCCAGCGGCGTT
ACGTGGAGTCCCTCTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTGGATTTCATCGAGGGTCTC
TCCCCGGCCGTCTCCATCGACCAGAAGTCGACATCGCGCAACCCGCGCTCGACGGTCGGCACCATCACGGAGGTCTACGA
CTACCTCCGCCTGCTCTTCGCCCGGATCGGCAAGCCGCACTGCCCCGAGTGCGGCCGCCCCATCGCCCGCCAGTCGCCGC
AGGCCATCGTGGACAAGGTCCTCGGCCTGCCCGAGGGCAGCCGCTTCCAGGTTCTCTCGCCGCTCGTCCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGACCTCCAGACCAAGGGGTACAGCCGCGCGAGGGTCGACGGCGTCACCATCCAGCT
CTCCGAGCCGCCCACGCTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACCGTCAAGGACAGCG
CCAAGCGCCGCCTCACCGACTCGGTGGAGACCGCCCTCGGCCTCTCCGGCGGCATGGTCGTCCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGGATGTATTCGGAGCACCTCTACTGCGCCTACGACGACCTCTCCTTCGAGGAGCT
CGAGCCGCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCGGACTGCACCGGCATCGGCACCCGTATGGAGGTCG
ACCCGGAGCTGATCGTCCCGGACGAGGAGAAGTCGCTCGACGAAGGGGCGATCCACCCCTGGTCCCACGGCCACACCAAG
GAGTACTTCGGCCGGCTGATCGGCGCCCTCGCCAAGGCCCTCGGCTTCCGTACGGACATCCCCTGGGCCGGACTCCCGCA
GCGCGCCAAGAAGGCCCTGCTCTACGGCCACAAGATCCAGACCGAGGTCCGCTACCGCAACCGGTACGGGCGCGAGCGCG
CCTACACCACGCCCGCCTTCGAGGGCGCGGTCCAGTTCGTCAAGCGGCGCCACACCGAGGCCGAGAGTGACTCCAGCCGC
GAGCGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCTCCCGGCTCAAGCCGATCGTCCTCGCGGT
GACGGTCATGGAGAAGTCCATCGCCGAGGTCTCCGCGATGTCGATCAGCGACTGCGCCGAGTTCCTCGGCCGCCTCAAGC
TGAACGCCCGCGACAAGAAGATCGCCGAGCGGGTGCTCAAGGAGGTCAACGAGCGGCTGAAGTTCCTGGTCGACGTCGGC
CTGGACTACCTCTCGCTCAACCGCGCGGCCGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGGCTCGCCACCCAGAT
CGGCTCCGGCCTGGTCGGCGTGCTGTACGTCCTGGACGAGCCGTCCATCGGCCTCCACCAGCGCGACAACCACCGGCTGA
TCGAGACCCTGGTCCGCCTCCGCGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACCATCAAGGTGGCC
GACTGGGTCGTCGACATCGGCCCCGGCGCCGGTGAGCACGGCGGCAAGGTCGTCCACTCCGGATCGCTCAAGGAGCTGCT
CTCCAACAAGGAGTCGGTCACCGGCCAGTATCTGTCCGGCAAGCGGTCCATCCCGACCCCGGACGTCCGCCGCCCGGTCG
ACCCCGAGCGCAGCCTCACGGTCCACGGCGCCCGCGAGAACAACCTGCACGACATCGACGTCTCCTTCCCGCTCGGCGTG
CTCACCGCCGTCACCGGAGTCTCCGGCTCCGGGAAGTCGACCCTGGTCAACGACATCCTCTACACCCACCTGGCCCGCGA
GCTGAACGGCGCCAAGTCGGTCCCCGGGCGCCACACCCGGGTCGACGGCGACGACCTGGTCGACAAGGTGGTCCACGTCG
ACCAGTCCCCGATCGGCCGGACCCCCCGGTCCAACCCGGCGACGTACACCGGGGTCTTCGACCACGTCCGCAAGCTCTTC
GCGGAGACGATGGAGGCGAAGGTGCGCGGCTATCTGCCGGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAA
CTGCTCCGGCGACGGCACGATCAAGATCGAGATGAACTTCCTGCCCGACGTGTACGTCCCGTGCGAGGTCTGCCACGGTG
CGCGCTACAACCGGGAGACCCTGGAGGTGCACTACAAGGGCAAGTCCATCGCCGAGGTGCTGGACATGCCGATCGAGGAG
GGCCTGGAGTTCTTCGAGGCCGTCCCGGCCATCGCCCGCCACCTCCGCACGCTCAACGACGTGGGTCTGGGGTACGTCCG
GCTCGGTCAGTCCGCGCCGACGCTCTCCGGCGGTGAGGCGCAGCGCGTCAAGCTGGCGAGCGAGCTGCAGAAGCGCTCCA
CCGGCCGCACGGTGTACGTCCTGGACGAGCCGACCACCGGTCTCCACTTCGAGGACATCAGCAAGCTGATCACCGTCCTC
TCCGGCCTGGTCGACAAGGGCAACTCGGTGATCGTCATCGAGCACAACCTGGACGTCATCAAGACCGCCGACTGGGTCAT
CGACATGGGCCCCGAAGGCGGGAACGGCGGCGGCATGGTCGTGGCCGAGGGCACGCCGGAGCAGGTCGCCTCGGTCCCCG
CCAGCCACACCGGGAAGTTCCTCCAGGGGATCCTGGACGCGGACCGGATCAGCGAGGCCGCGGTGCCGTCGGGGCGTGGC
GCGGCCCGTAGGACCGCCGCCCGGAAGACCACCGCGGCGAAGAAGACGGCGGCGCCGAAGAAGGCCGCCACCGCCACCAA
GAAGGCCGCGGCGACCAAGGCCACCGCGAAGAAGGCGACGCGCGCCCGCAAGGCGTGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(629-865)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-404)

UvrA interaction domain (UvrA_inter)

(131-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.691

94.428

0.535
  uvrA Streptococcus pneumoniae TIGR4

56.691

94.428

0.535
  uvrA Streptococcus pneumoniae D39

56.691

94.428

0.535

Multiple sequence alignment