Detailed information NTG0153453

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A6E92_RS17230
• Genome accession: NZ_CP015362
• Coordinates: 4061205..4063811 (+)
• Length: 868 a.a.
• NCBI ID: WP_084994077.1
• Uniprot ID: -
• Organism: Streptomyces sp. S8
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4056205..4068811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6E92_RS17195 (A6E92_16885)	dnaJ	4056519..4057709 (+)	1191	WP_018489589.1	molecular chaperone DnaJ	-
A6E92_RS17200 (A6E92_16890)	-	4057711..4058166 (+)	456	WP_018489588.1	helix-turn-helix domain-containing protein	-
A6E92_RS17205 (A6E92_16895)	-	4058321..4058741 (-)	421	Protein_3409	helix-turn-helix transcriptional regulator	-
A6E92_RS17210 (A6E92_16900)	-	4058812..4059657 (-)	846	WP_018489586.1	hypothetical protein	-
A6E92_RS33835	-	4059806..4060111 (+)	306	WP_229865776.1	hypothetical protein	-
A6E92_RS17220 (A6E92_16910)	-	4060108..4060428 (+)	321	WP_015609572.1	hypothetical protein	-
A6E92_RS33210 (A6E92_16915)	-	4060572..4060973 (-)	402	WP_028415997.1	TIGR03618 family F420-dependent PPOX class oxidoreductase	-
A6E92_RS17230 (A6E92_16920)	clpC	4061205..4063811 (+)	2607	WP_084994077.1	ATP-dependent chaperone ClpB	Regulator
A6E92_RS17235 (A6E92_16925)	-	4064206..4064757 (+)	552	WP_018489582.1	YbjN domain-containing protein	-
A6E92_RS17240 (A6E92_16930)	-	4064830..4066005 (-)	1176	WP_084994079.1	pyridoxal phosphate-dependent aminotransferase	-
A6E92_RS17245 (A6E92_16935)	-	4066224..4066487 (+)	264	WP_202536733.1	hypothetical protein	-
A6E92_RS17250 (A6E92_16940)	-	4066843..4067364 (+)	522	WP_084994081.1	DUF2617 family protein	-

Sequence

Protein

• Length: 868 a.a.
• Molecular weight: 94761.21 Da
• Isoelectric Point: 4.7100

>NTDB_id=153453 A6E92_RS17230 WP_084994077.1 4061205..4063811(+) (clpC) [Streptomyces sp. S8]
MDAELTNKSRDAINAASDRAVKDGHPDLTPGHLLLALLGGQDNENITDLLTAVEADQAVVRAGAEKLLGGLPSVTGSTVA
PPQPDRELLAVIQDAAQRAKELGDEYLSTEHLLIGIAAKGGRAGEILDGQGATAKKLLAAFETSRGGRRVTTPDPEGQYK
ALEKFGTDFTAAARDGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKNKRLVS
LDLGAMVAGAKYRGEFEERLKTVLSEIKESDGQIITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPSVEDTIAILRGLKGRYEAHHKVQIADSALVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPLEIDELQRSVDRLRMEELALKNESDAASKQRLEKLRRDLADKEEELRGLNARWEKEKQGLNRVGELKER
LDELRGQAERAQRDGDFDAASKLLYGEIPGLERELEEAAEAEQEASKDTMVKEEVGPDDIADVVGAWTGIPAGRLLEGET
QKLLRMESELGKRLIGQTEAVQAVSDAVRRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMIRIDMSE
YGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILVL
TSNLGSQFLMDPLVKPEVKKEQVLEVVRASFKPEFINRLDDLVVFSALSGDELAHIAGLQIDRLAKRLADRRLTLDVTPE
ALAWLAQEGNDPAYGARPLRRLIQTAIGDRLAKEILSGEIRDGDTVRVDRAQEEDEGGLTVGPAPRTS

Nucleotide

• Length: 2607 bp

>NTDB_id=153453 A6E92_RS17230 WP_084994077.1 4061205..4063811(+) (clpC) [Streptomyces sp. S8]
GTGGACGCCGAGCTGACCAACAAGAGCCGGGACGCCATCAACGCGGCCAGTGACCGGGCCGTGAAGGACGGGCACCCCGA
CCTCACCCCCGGCCATCTGCTCCTCGCACTGCTGGGGGGCCAGGACAACGAGAACATCACCGACCTGCTCACCGCCGTCG
AGGCCGACCAGGCCGTCGTGCGCGCCGGGGCCGAGAAGCTGCTCGGCGGCCTCCCCAGCGTCACCGGCTCCACCGTCGCC
CCGCCGCAGCCCGACCGTGAGCTGCTGGCGGTGATCCAGGACGCGGCGCAGCGGGCCAAGGAGCTGGGCGACGAGTACCT
CTCCACCGAGCACCTGCTCATCGGCATCGCCGCGAAGGGCGGCCGCGCCGGTGAGATCCTCGACGGACAGGGGGCCACCG
CCAAGAAGCTGCTGGCCGCATTCGAGACGAGCAGGGGAGGGCGCCGGGTGACCACACCCGACCCGGAGGGGCAGTACAAG
GCCCTGGAGAAGTTCGGCACCGACTTCACGGCCGCCGCGCGCGACGGAAAGCTGGACCCGGTCATCGGCCGCGACCAGGA
GATCCGCCGTGTCGTGCAGGTGCTCTCGCGCCGGACGAAGAACAACCCGGTGCTCATCGGTGAGCCCGGCGTCGGCAAGA
CCGCCGTCGTCGAAGGGCTCGCCCAGCGCATCGTCAAGGGCGACGTCCCCGAGAGCCTGAAGAACAAGCGGCTGGTCTCG
CTGGACCTGGGCGCGATGGTCGCGGGTGCGAAGTACCGCGGCGAGTTCGAGGAGCGGCTGAAGACCGTCCTCTCCGAGAT
CAAGGAGAGCGACGGCCAGATCATCACCTTCATCGACGAGCTGCACACCGTCGTCGGCGCCGGCGCGGGCGGCGACTCCG
CCATGGACGCGGGCAACATGCTCAAGCCGATGCTGGCCCGCGGCGAGCTGCGCATGGTCGGCGCGACCACGCTCGACGAG
TACCGCGAGCGGATCGAGAAGGACCCCGCCCTGGAGCGCCGCTTCCAGCAGGTGCTGGTGGCCGAGCCGTCCGTCGAGGA
CACCATCGCCATCCTCCGTGGCCTCAAGGGCCGTTACGAGGCCCACCACAAGGTCCAGATCGCGGACTCGGCGCTCGTCG
CCGCCGCCACCCTCTCCGACCGCTACATCACCTCCCGCTTCCTCCCCGACAAGGCCATCGACCTGGTCGACGAGGCCGCC
TCCCGGCTCCGCATGGAGATCGACTCCTCGCCTCTGGAGATCGACGAACTCCAGCGCTCCGTCGACCGGTTGCGCATGGA
GGAGCTGGCGCTGAAGAACGAGTCCGACGCCGCCTCCAAGCAGCGGCTGGAGAAGCTGCGCCGCGACCTCGCCGACAAGG
AGGAGGAGCTGCGCGGCCTCAACGCCCGCTGGGAGAAGGAGAAGCAGGGCCTGAACCGGGTCGGTGAGCTGAAGGAGCGC
CTCGACGAGCTGCGCGGCCAGGCCGAACGGGCCCAGCGCGACGGCGACTTCGACGCCGCCTCCAAGCTGCTGTACGGGGA
GATCCCGGGCCTGGAGCGGGAGTTGGAGGAGGCCGCCGAGGCGGAGCAGGAGGCCTCCAAGGACACCATGGTCAAGGAGG
AGGTCGGGCCGGACGACATCGCGGACGTCGTCGGCGCCTGGACCGGCATCCCGGCAGGGCGGCTGCTGGAGGGCGAGACG
CAGAAGCTGCTGCGGATGGAGAGCGAACTCGGCAAGCGGCTGATCGGGCAGACCGAGGCCGTGCAGGCCGTCTCCGACGC
CGTACGCCGGACCAGGGCGGGCATCGCCGATCCCGACCGGCCCACCGGGTCGTTCCTCTTCCTCGGGCCCACGGGCGTCG
GCAAGACCGAGCTGGCCAAGGCGCTCGCCGACTTCCTCTTCGACGACGAGCGGGCCATGATCCGCATCGACATGAGCGAG
TACGGCGAGAAGCACAGCGTCGCCCGCCTGGTCGGTGCCCCGCCCGGTTACGTCGGGTACGAGGAGGGCGGCCAGCTCAC
CGAGGCCGTCCGCCGCCGCCCGTACAGCGTCGTGCTCCTGGACGAGGTCGAAAAGGCCCACCCCGAGGTCTTCGACATCC
TGCTCCAGGTCCTCGACGACGGCCGGCTCACCGACGGCCAGGGCCGCACGGTCGACTTCCGCAACACCATCCTCGTCCTC
ACCTCCAACCTCGGCAGCCAGTTCCTGATGGACCCGCTGGTCAAGCCCGAGGTGAAGAAGGAGCAGGTCCTGGAGGTGGT
GAGGGCCTCCTTCAAGCCGGAGTTCATCAACCGGCTGGACGACCTGGTGGTCTTCTCGGCCCTCTCCGGTGACGAACTGG
CCCACATCGCGGGCCTCCAGATCGACCGGCTGGCCAAGCGCCTCGCGGACCGCCGCCTCACCCTGGACGTCACCCCCGAG
GCGCTCGCCTGGCTGGCCCAGGAGGGCAACGACCCGGCGTACGGGGCGCGCCCGCTGCGCCGCCTCATCCAGACGGCCAT
CGGGGACCGGCTCGCCAAGGAGATCCTCTCCGGCGAGATCCGGGACGGCGACACCGTACGGGTGGACCGCGCCCAGGAGG
AGGACGAGGGCGGCCTGACCGTGGGCCCGGCCCCCCGGACCTCGTGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

• AAA lid domain (AAA_lid_9) (344-446)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-69)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-761)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.06	99.885	0.44
clpC	Lactococcus lactis subsp. cremoris KW2	47.25	81.682	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.469	81.567	0.379