Detailed information NTG0153446

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: AKO65_RS12135
• Genome accession: NZ_CP012329
• Coordinates: 2410911..2411714 (+)
• Length: 267 a.a.
• NCBI ID: WP_008342226.1
• Uniprot ID: A0A5K1NAR3
• Organism: Bacillus altitudinis strain NJ-M2
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 2405911..2416714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AKO65_RS12120 (AKO65_12120)	ahrC	2406934..2407383 (+)	450	WP_007501163.1	transcriptional regulator AhrC/ArgR	-
AKO65_RS12125 (AKO65_12125)	recN	2407418..2409151 (+)	1734	WP_008342224.1	DNA repair protein RecN	Machinery gene
AKO65_RS12130 (AKO65_12130)	spoIVB	2409350..2410627 (+)	1278	WP_008342225.1	SpoIVB peptidase	-
AKO65_RS12135 (AKO65_12135)	spo0A	2410911..2411714 (+)	804	WP_008342226.1	sporulation transcription factor Spo0A	Regulator
AKO65_RS12140 (AKO65_12140)	-	2412164..2413264 (+)	1101	WP_007501159.1	Rap family tetratricopeptide repeat protein	-
AKO65_RS12145 (AKO65_12145)	-	2413491..2414228 (+)	738	WP_048001396.1	glycerophosphodiester phosphodiesterase	-
AKO65_RS12150 (AKO65_12150)	-	2414262..2414498 (-)	237	WP_017357960.1	DUF2627 domain-containing protein	-

Sequence

Protein

• Length: 267 a.a.
• Molecular weight: 29891.41 Da
• Isoelectric Point: 6.3918

>NTDB_id=153446 AKO65_RS12135 WP_008342226.1 2410911..2411714(+) (spo0A) [Bacillus altitudinis strain NJ-M2]
MEKIKVCVADDNRELVGLLTEYIEGQEDMEVLGVAYNGQECLTLFKDKEPDVLLLDIIMPHLDGLAVLERLRENNEMTKQ
PSVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNGTQVSHRSSSIQNSVLRSKPEPKRKNLDASITTI
IHEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTV
SMSKAKPTNSEFIAMVADRLRLEHRAS

Nucleotide

• Length: 804 bp

>NTDB_id=153446 AKO65_RS12135 WP_008342226.1 2410911..2411714(+) (spo0A) [Bacillus altitudinis strain NJ-M2]
GTGGAGAAAATTAAAGTGTGTGTAGCTGATGACAATCGAGAACTTGTTGGCCTTTTGACAGAGTATATTGAGGGACAGGA
AGATATGGAAGTACTTGGCGTGGCGTATAATGGTCAGGAATGTCTGACATTATTTAAAGATAAAGAGCCCGACGTTCTCC
TCTTAGATATTATCATGCCTCATTTAGACGGTCTTGCTGTACTGGAACGCCTCCGTGAAAACAATGAAATGACTAAACAG
CCAAGTGTCATTATGCTGACGGCTTTCGGACAAGAAGACGTAACGAAAAAAGCAGTCGATTTGGGCGCATCCTATTTCAT
TTTGAAACCATTCGATATGGAAAACCTCGTAGGTCATATTCGTCAAGTCAGTGGAAACGGCACACAAGTCAGCCATCGAT
CTTCATCTATCCAAAACAGTGTCCTTCGCAGCAAACCTGAACCGAAACGTAAGAACTTAGATGCGAGCATTACGACGATT
ATTCATGAGATTGGCGTGCCAGCTCATATTAAAGGCTATTTATACTTAAGAGAAGCCATTTCGATGGTGTACAATGATAT
TGAACTACTCGGCAGTATTACAAAAGTATTGTACCCAGACATTGCAAAGAAATTTAACACGACAGCCAGCAGGGTAGAAC
GAGCGATTCGTCATGCCATTGAAGTGGCTTGGAGCAGAGGGAATATTGACTCCATTTCGTCACTCTTTGGCTACACAGTC
AGCATGTCAAAAGCCAAACCGACCAATTCCGAATTTATTGCCATGGTGGCTGATCGACTGCGTTTAGAGCATAGAGCAAG
CTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-120)

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (157-260)

3D structure

• AlphaFold DB: A0A5K1NAR3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	88.06	100	0.884