Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   NX99_RS09215 Genome accession   NZ_CP015282
Coordinates   1972869..1973606 (+) Length   245 a.a.
NCBI ID   WP_022496803.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1967869..1978606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS09200 (NX99_09045) - 1968847..1969599 (+) 753 WP_073688109.1 DUF4767 domain-containing protein -
  NX99_RS09205 (NX99_09050) tehB 1969683..1970561 (-) 879 WP_049545576.1 SAM-dependent methyltransferase TehB -
  NX99_RS09210 (NX99_09055) - 1971342..1972655 (-) 1314 WP_049545446.1 matrixin family metalloprotease -
  NX99_RS09215 (NX99_09060) comE/comE1 1972869..1973606 (+) 738 WP_022496803.1 LytR/AlgR family response regulator transcription factor Regulator
  NX99_RS09220 (NX99_09065) - 1973917..1975095 (+) 1179 WP_002884300.1 sensor histidine kinase -
  NX99_RS09225 (NX99_09070) - 1975207..1976586 (+) 1380 WP_084915407.1 hypothetical protein -
  NX99_RS09230 (NX99_09075) rpsP 1976749..1977021 (+) 273 WP_002884675.1 30S ribosomal protein S16 -
  NX99_RS09235 (NX99_09080) - 1977033..1977281 (+) 249 WP_002884680.1 KH domain-containing protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28035.97 Da        Isoelectric Point: 4.7123

>NTDB_id=153082 NX99_RS09215 WP_022496803.1 1972869..1973606(+) (comE/comE1) [Streptococcus salivarius strain ATCC 27945]
MLSIIVLEDDALQRHRVSRLLDEAVEESKAVVDGITFYEQGQELLDADRGSGKSMVYLLDIDLKNQTKQGLDIGLEIRKE
DLKAQIAFVTAYSEFMPLTFRYKIQALDFVDKSMEDADLKRALVELLDFAYSQVEQETKAQSLTVKTDKNDVNIPYDDIL
YIETAPVPHKLIAHTKSNLVEFYGKIAEVAKLDDIFFQTHRSFVVNVSNVTSVDRTANMVFFEGDESCLLSRTRKKELLE
RLKNR

Nucleotide


Download         Length: 738 bp        

>NTDB_id=153082 NX99_RS09215 WP_022496803.1 1972869..1973606(+) (comE/comE1) [Streptococcus salivarius strain ATCC 27945]
ATGCTTTCTATTATCGTCCTTGAAGATGATGCCTTGCAGCGTCATCGTGTTAGCCGTTTATTGGACGAAGCAGTTGAGGA
GTCGAAGGCCGTTGTTGATGGGATTACCTTTTATGAGCAGGGGCAAGAATTGTTAGATGCTGATAGAGGTTCGGGTAAAT
CCATGGTTTATCTTTTGGATATTGACCTTAAAAATCAAACGAAGCAGGGACTAGATATTGGGCTTGAAATCCGTAAGGAA
GACTTGAAAGCACAAATCGCTTTTGTTACAGCCTACTCTGAGTTTATGCCCTTGACCTTCCGTTATAAGATTCAAGCTCT
GGACTTTGTTGATAAATCCATGGAAGATGCAGATCTTAAGAGAGCCTTGGTAGAACTTTTAGATTTTGCGTATTCGCAGG
TTGAGCAAGAAACCAAGGCACAGAGTCTGACGGTGAAAACGGATAAAAATGATGTTAATATTCCTTATGATGACATTTTA
TACATTGAAACAGCCCCTGTGCCACATAAGTTGATCGCTCACACCAAGTCAAATCTAGTAGAATTCTATGGAAAAATTGC
AGAAGTAGCGAAATTGGATGATATTTTCTTCCAAACGCATCGCTCTTTTGTTGTCAATGTGAGTAATGTGACAAGTGTGG
ATCGTACGGCTAATATGGTCTTCTTTGAGGGAGACGAGTCATGCCTCCTCTCGCGGACACGTAAAAAGGAACTTTTGGAA
CGATTGAAAAATCGTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

37.037

99.184

0.367