Detailed information    

insolico Bioinformatically predicted

Overview


Name   CJE0566   Type   Regulator
Locus tag   AEI09_RS03465 Genome accession   NZ_CP012248
Coordinates   647280..647933 (-) Length   217 a.a.
NCBI ID   WP_087693356.1    Uniprot ID   A0A5T0ZJ63
Organism   Campylobacter jejuni strain CJ514CC45     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 635454..664257 647280..647933 within 0


Gene organization within MGE regions


Location: 635454..664257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AEI09_RS03370 (AEI09_03380) - 635454..636656 (+) 1203 WP_002875038.1 tyrosine-type recombinase/integrase -
  AEI09_RS03375 (AEI09_03385) - 636653..636823 (-) 171 WP_002864902.1 helix-turn-helix transcriptional regulator -
  AEI09_RS03380 (AEI09_03390) - 636816..637358 (-) 543 WP_038402049.1 pentapeptide repeat-containing protein -
  AEI09_RS03385 (AEI09_03395) - 637477..638142 (-) 666 WP_087693351.1 hypothetical protein -
  AEI09_RS03390 (AEI09_03400) - 638148..638498 (-) 351 WP_002875041.1 hypothetical protein -
  AEI09_RS03395 (AEI09_03405) - 638501..639226 (-) 726 WP_052805321.1 Rha family transcriptional regulator -
  AEI09_RS03400 (AEI09_03415) - 639353..640054 (-) 702 WP_251814135.1 helix-turn-helix domain-containing protein -
  AEI09_RS03405 (AEI09_03420) - 640065..640904 (-) 840 WP_002861640.1 hypothetical protein -
  AEI09_RS03410 (AEI09_03425) - 641002..641214 (-) 213 WP_052783907.1 hypothetical protein -
  AEI09_RS03415 (AEI09_03430) - 641255..641524 (-) 270 WP_052798614.1 hypothetical protein -
  AEI09_RS03420 (AEI09_03435) - 641505..642200 (-) 696 WP_052799615.1 hypothetical protein -
  AEI09_RS03425 (AEI09_03440) - 642200..643132 (-) 933 WP_087693354.1 recombinase RecT -
  AEI09_RS03430 (AEI09_03445) - 643134..643988 (-) 855 WP_059118349.1 lambda-exonuclease family protein -
  AEI09_RS03435 (AEI09_03450) - 643990..644217 (-) 228 WP_002874355.1 helix-turn-helix domain-containing protein -
  AEI09_RS03440 (AEI09_03455) - 644208..644465 (-) 258 WP_002865124.1 hypothetical protein -
  AEI09_RS03445 (AEI09_03460) - 644456..644725 (-) 270 WP_002874357.1 hypothetical protein -
  AEI09_RS03450 (AEI09_03465) - 645285..645557 (-) 273 WP_052805323.1 hypothetical protein -
  AEI09_RS03455 (AEI09_03470) - 645701..646432 (+) 732 WP_002861653.1 hypothetical protein -
  AEI09_RS03460 (AEI09_03475) - 646466..647293 (-) 828 WP_052805324.1 hypothetical protein -
  AEI09_RS03465 (AEI09_03480) CJE0566 647280..647933 (-) 654 WP_087693356.1 DNA/RNA non-specific endonuclease Regulator
  AEI09_RS03470 (AEI09_03485) - 647977..648249 (-) 273 WP_002795981.1 hypothetical protein -
  AEI09_RS03475 (AEI09_03490) - 648230..649126 (-) 897 WP_002874367.1 hypothetical protein -
  AEI09_RS03480 (AEI09_03495) - 649166..649900 (-) 735 WP_002874368.1 helix-turn-helix transcriptional regulator -
  AEI09_RS03485 (AEI09_03500) - 650012..650230 (+) 219 WP_002826741.1 hypothetical protein -
  AEI09_RS03490 (AEI09_03505) - 650227..650697 (+) 471 WP_087693358.1 hypothetical protein -
  AEI09_RS03495 (AEI09_03510) - 650657..651034 (+) 378 WP_087693360.1 hypothetical protein -
  AEI09_RS03500 (AEI09_03515) - 651031..652032 (+) 1002 WP_087693362.1 hypothetical protein -
  AEI09_RS03505 (AEI09_03520) - 652042..652689 (+) 648 WP_052798608.1 hypothetical protein -
  AEI09_RS03510 (AEI09_03525) - 652707..653087 (+) 381 WP_260629774.1 hypothetical protein -
  AEI09_RS03515 (AEI09_03530) - 653087..653473 (+) 387 WP_002861661.1 terminase small subunit -
  AEI09_RS03520 (AEI09_03535) - 653470..654762 (+) 1293 WP_087693364.1 terminase -
  AEI09_RS03525 (AEI09_03540) - 654752..655024 (+) 273 WP_002781524.1 hypothetical protein -
  AEI09_RS03530 (AEI09_03545) - 655005..656543 (+) 1539 WP_048818586.1 hypothetical protein -
  AEI09_RS03535 (AEI09_03550) - 656536..656739 (+) 204 WP_000931940.1 hypothetical protein -
  AEI09_RS03540 (AEI09_03555) - 656729..657376 (+) 648 WP_048818588.1 hypothetical protein -
  AEI09_RS03545 (AEI09_03560) - 657387..657767 (+) 381 WP_002791792.1 hypothetical protein -
  AEI09_RS03550 (AEI09_03565) - 658027..659211 (+) 1185 WP_260629775.1 hypothetical protein -
  AEI09_RS03555 (AEI09_03570) - 659211..662843 (+) 3633 WP_192865619.1 hypothetical protein -
  AEI09_RS03560 (AEI09_03575) - 663223..664257 (+) 1035 WP_002875076.1 DUF5309 family protein -

Sequence


Protein


Download         Length: 217 a.a.        Molecular weight: 25585.12 Da        Isoelectric Point: 9.9170

>NTDB_id=152964 AEI09_RS03465 WP_087693356.1 647280..647933(-) (CJE0566) [Campylobacter jejuni strain CJ514CC45]
MKKLIILPLLSTLALADYTQYKPSEDFAKYFTKQNCSQVLDKFYYLNCYDYNYKGTRAVAYRLEADNLKGEQIKKRPRFE
DDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVL
NLVNYDNNPQRIRNQIAIPSSYTKILKGENFKECYQVPNHEVEDESIKKYKVNCGKF

Nucleotide


Download         Length: 654 bp        

>NTDB_id=152964 AEI09_RS03465 WP_087693356.1 647280..647933(-) (CJE0566) [Campylobacter jejuni strain CJ514CC45]
ATGAAAAAACTTATAATCTTACCATTGTTATCCACTCTAGCCTTAGCTGATTATACACAATACAAACCAAGTGAAGATTT
TGCTAAGTATTTTACTAAGCAAAACTGCTCACAAGTTTTAGATAAATTCTATTATCTAAATTGCTATGATTATAATTATA
AAGGCACTAGAGCCGTAGCTTATAGATTAGAAGCGGATAATTTAAAAGGTGAACAAATCAAAAAACGCCCACGCTTTGAA
GATGATACAAATATACCTAAAAAATACCGCACTACATGGAGTGATTATAAAAACAGCGGTTATGATAGAGGGCACACTCT
TTCTAATGCTTCAATGAGAAAAACAACTCAAGCTCAAAGAAGCACTTTTTTAATGAGTAATATTACTCCGCAAAATCCAC
AGATCAATCAAAGGGTTTGGAACAAGATTGAAAAAAGAGAAAGACAAGTAGCTTTAAAGCTTGGAAGTTTAGAAGTTTTA
AATTTGGTTAATTATGATAATAATCCACAAAGAATAAGAAATCAAATTGCCATTCCAAGCTCTTACACTAAGATTTTAAA
AGGCGAGAATTTTAAAGAATGTTACCAAGTACCAAATCATGAAGTTGAAGATGAGAGTATAAAAAAATATAAGGTTAATT
GTGGCAAATTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A5T0ZJ63

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  CJE0566 Campylobacter jejuni RM1221

92.627

100

0.926

  CJE1441 Campylobacter jejuni RM1221

91.705

100

0.917


Multiple sequence alignment