Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   A4265_RS08385 Genome accession   NZ_CP015238
Coordinates   1685271..1686038 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NS53     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1680271..1691038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4265_RS08375 (A4265_07960) - 1681953..1683098 (-) 1146 WP_063629731.1 tyrosine-type recombinase/integrase -
  A4265_RS08380 (A4265_07965) dinD 1683354..1684208 (-) 855 WP_047236050.1 DNA damage-inducible protein D -
  A4265_RS08385 (A4265_07975) irvR 1685271..1686038 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  A4265_RS08390 (A4265_07980) - 1686192..1686398 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  A4265_RS08395 (A4265_07985) - 1686432..1687199 (+) 768 WP_076612478.1 BRO family protein -
  A4265_RS08400 (A4265_07990) - 1687209..1687832 (+) 624 WP_063632180.1 Bro-N domain-containing protein -
  A4265_RS08405 (A4265_07995) - 1687859..1688101 (+) 243 WP_000648623.1 hypothetical protein -
  A4265_RS09045 - 1688360..1688530 (+) 171 WP_021775540.1 hypothetical protein -
  A4265_RS08410 (A4265_08000) - 1688754..1688927 (+) 174 WP_000074663.1 plasmid mobilization protein -
  A4265_RS08415 (A4265_08005) - 1689013..1689519 (+) 507 WP_063629729.1 hypothetical protein -
  A4265_RS08420 (A4265_08010) - 1689685..1689963 (+) 279 WP_136282179.1 hypothetical protein -
  A4265_RS08425 (A4265_08015) - 1689950..1690171 (+) 222 WP_010922763.1 hypothetical protein -
  A4265_RS08430 (A4265_08020) - 1690174..1690365 (+) 192 WP_010922764.1 hypothetical protein -
  A4265_RS08435 (A4265_08025) - 1690377..1690706 (+) 330 WP_063629727.1 hypothetical protein -
  A4265_RS08440 (A4265_08030) - 1690709..1690981 (+) 273 WP_001100459.1 hypothetical protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=152735 A4265_RS08385 WP_003058809.1 1685271..1686038(-) (irvR) [Streptococcus pyogenes strain NS53]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=152735 A4265_RS08385 WP_003058809.1 1685271..1686038(-) (irvR) [Streptococcus pyogenes strain NS53]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4