Detailed information NTG0151500

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACO02_RS07465
• Genome accession: NZ_CP012120
• Coordinates: 1474705..1475592 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300_2014.C02
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1469705..1480592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACO02_RS07435 (ACO02_0998)	-	1470437..1471198 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
ACO02_RS07440 (ACO02_0999)	-	1471443..1471898 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACO02_RS15620 (ACO02_03560)	-	1472020..1472121 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACO02_RS07450 (ACO02_1000)	-	1472181..1473605 (-)	1425	WP_000953744.1	alkaline phosphatase	-
ACO02_RS07455 (ACO02_1001)	-	1473803..1474003 (+)	201	WP_000604728.1	hypothetical protein	-
ACO02_RS07460 (ACO02_1002)	braR	1474029..1474694 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACO02_RS07465 (ACO02_1003)	braS	1474705..1475592 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACO02_RS07470 (ACO02_1004)	-	1475700..1476455 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACO02_RS07475 (ACO02_1005)	-	1476452..1478452 (+)	2001	WP_000776751.1	ABC transporter permease	-
ACO02_RS07480 (ACO02_03565)	-	1479111..1479224 (+)	114	WP_001791776.1	hypothetical protein	-
ACO02_RS07490 (ACO02_03575)	-	1479606..1479866 (+)	261	WP_001789910.1	hypothetical protein	-
ACO02_RS07495 (ACO02_1007)	-	1479876..1480373 (+)	498	WP_001065268.1	glutathione peroxidase	-
ACO02_RS07500 (ACO02_03580)	-	1480481..1480573 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=151500 ACO02_RS07465 WP_000143419.1 1474705..1475592(+) (braS) [Staphylococcus aureus strain USA300_2014.C02]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=151500 ACO02_RS07465 WP_000143419.1 1474705..1475592(+) (braS) [Staphylococcus aureus strain USA300_2014.C02]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997