Detailed information NTG0150363

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAGV88_RS10805
• Genome accession: NZ_CP012018
• Coordinates: 2113306..2114349 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Gv88
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2108306..2119349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAGV88_RS10775 (SAGV88_02189)	-	2108724..2109980 (-)	1257	WP_001795438.1	aminopeptidase	-
SAGV88_RS10780 (SAGV88_02190)	-	2109983..2110183 (-)	201	WP_000180461.1	DUF1128 family protein	-
SAGV88_RS10785 (SAGV88_02191)	-	2110330..2110794 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SAGV88_RS10790 (SAGV88_02192)	-	2110801..2111076 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAGV88_RS10795 (SAGV88_02194)	-	2111354..2112571 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SAGV88_RS10800 (SAGV88_02195)	vraR	2112687..2113316 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
SAGV88_RS10805 (SAGV88_02196)	vraS	2113306..2114349 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SAGV88_RS10810 (SAGV88_02197)	liaF	2114346..2115047 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SAGV88_RS10815 (SAGV88_02198)	-	2115062..2115448 (-)	387	WP_001110179.1	hypothetical protein	-
SAGV88_RS10820 (SAGV88_02199)	map	2115665..2116423 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAGV88_RS10825 (SAGV88_02200)	-	2116895..2117881 (+)	987	WP_000999713.1	FUSC family protein	-
SAGV88_RS10830 (SAGV88_02202)	-	2118312..2118725 (-)	414	WP_001549145.1	hypothetical protein	-
SAGV88_RS10835	-	2118754..2118864 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=150363 SAGV88_RS10805 WP_001017131.1 2113306..2114349(-) (vraS) [Staphylococcus aureus strain Gv88]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=150363 SAGV88_RS10805 WP_001017131.1 2113306..2114349(-) (vraS) [Staphylococcus aureus strain Gv88]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1