Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SAHC1340_RS11925 Genome accession   NZ_CP012011
Coordinates   2292757..2293473 (+) Length   238 a.a.
NCBI ID   WP_031913507.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HC1340     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2287757..2298473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAHC1340_RS11895 (SAHC1340_03020) - 2287976..2288602 (+) 627 WP_000522384.1 nitroreductase family protein -
  SAHC1340_RS11900 (SAHC1340_03022) - 2288963..2289748 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  SAHC1340_RS17165 (SAHC1340_03023) hld 2290345..2290425 (-) 81 WP_000046022.1 delta-hemolysin -
  SAHC1340_RS11910 (SAHC1340_03024) agrB 2290715..2291284 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  SAHC1340_RS11915 (SAHC1340_03025) agrD 2291281..2291421 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  SAHC1340_RS11920 (SAHC1340_03267) agrC 2291446..2292738 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  SAHC1340_RS11925 (SAHC1340_03274) agrA 2292757..2293473 (+) 717 WP_031913507.1 quorum-sensing response regulator AgrA Regulator
  SAHC1340_RS11930 (SAHC1340_03029) - 2293545..2293652 (+) 108 WP_001790167.1 hypothetical protein -
  SAHC1340_RS11935 (SAHC1340_03030) - 2293840..2294799 (-) 960 WP_001253313.1 carbohydrate kinase family protein -
  SAHC1340_RS11940 (SAHC1340_03031) - 2294796..2296280 (-) 1485 WP_000141417.1 sucrose-6-phosphate hydrolase -
  SAHC1340_RS11945 (SAHC1340_03032) - 2296429..2297379 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27939.92 Da        Isoelectric Point: 6.0927

>NTDB_id=150197 SAHC1340_RS11925 WP_031913507.1 2292757..2293473(+) (agrA) [Staphylococcus aureus strain HC1340]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIFFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=150197 SAHC1340_RS11925 WP_031913507.1 2292757..2293473(+) (agrA) [Staphylococcus aureus strain HC1340]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTTTTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment