Detailed information NTG0149401

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: AAV34_RS02710
• Genome accession: NZ_CP011937
• Coordinates: 534799..535962 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain CBMB205
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 529799..540962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAV34_RS02690 (AAV34_02655)	tuaH	530239..531435 (+)	1197	WP_032876154.1	teichuronic acid biosynthesis protein TuaH	-
AAV34_RS02695 (AAV34_02660)	-	531568..532644 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
AAV34_RS02700 (AAV34_02665)	-	532743..533924 (-)	1182	WP_032876157.1	LCP family protein	-
AAV34_RS02705 (AAV34_02670)	-	533929..534576 (-)	648	WP_007614107.1	YigZ family protein	-
AAV34_RS02710 (AAV34_02675)	degS	534799..535962 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
AAV34_RS02715 (AAV34_02680)	degU	536039..536728 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
AAV34_RS02720 (AAV34_02685)	-	536826..537674 (+)	849	WP_032876160.1	DegV family protein	-
AAV34_RS02725 (AAV34_02690)	comFA	537783..539168 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
AAV34_RS02730 (AAV34_02695)	-	539226..539510 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
AAV34_RS02735 (AAV34_02700)	comFC	539516..540205 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
AAV34_RS02740 (AAV34_02705)	-	540279..540698 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=149401 AAV34_RS02710 WP_007407484.1 534799..535962(+) (degS) [Bacillus velezensis strain CBMB205]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=149401 AAV34_RS02710 WP_007407484.1 534799..535962(+) (degS) [Bacillus velezensis strain CBMB205]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951