Detailed information NTG0149350

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A1D13_RS08875
• Genome accession: NZ_CP014759
• Coordinates: 1938391..1940967 (+)
• Length: 858 a.a.
• NCBI ID: WP_027219801.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain F4468
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1933391..1945967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A1D13_RS08845 (A1D13_08665)	-	1933668..1934036 (-)	369	WP_011946703.1	HesB/IscA family protein	-
A1D13_RS08850 (A1D13_08670)	-	1934041..1934424 (-)	384	WP_010947471.1	iron-sulfur cluster assembly scaffold protein	-
A1D13_RS08855 (A1D13_08675)	-	1934421..1935554 (-)	1134	WP_013101521.1	IscS subfamily cysteine desulfurase	-
A1D13_RS08860 (A1D13_08680)	trmJ	1935559..1936332 (-)	774	WP_011946705.1	tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ	-
A1D13_RS08865 (A1D13_08685)	-	1936448..1937233 (+)	786	WP_010947474.1	inositol monophosphatase family protein	-
A1D13_RS08870 (A1D13_08690)	-	1937346..1938302 (-)	957	WP_011946706.1	S49 family peptidase	-
A1D13_RS08875 (A1D13_08695)	clpC	1938391..1940967 (+)	2577	WP_027219801.1	ATP-dependent chaperone ClpB	Regulator
A1D13_RS08880 (A1D13_08700)	-	1941059..1942369 (-)	1311	WP_014844130.1	lpg1751 family Dot/Icm T4SS effector	-
A1D13_RS08885 (A1D13_08705)	-	1942382..1943029 (-)	648	WP_072356259.1	lpg1752 family Dot/Icm T4SS effector	-
A1D13_RS08890 (A1D13_08710)	mpl	1943322..1944689 (-)	1368	WP_027219800.1	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	-
A1D13_RS08895 (A1D13_08715)	-	1944691..1945311 (-)	621	WP_027219799.1	hypothetical protein	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 95792.62 Da
• Isoelectric Point: 5.4347

>NTDB_id=149350 A1D13_RS08875 WP_027219801.1 1938391..1940967(+) (clpC) [Legionella pneumophila strain F4468]
MRMDKLTSKFQMALADAQSLALGRDNGFIEPEHLMKALLDQQGGSCRPLLSKAGVNIPLLRTLIDQALDKLPKVSGTGGD
IHISNALNRLLNLTDKLSQQRKDNFISSELFVLAAINEDSNLAKILKQAGGDNKAIEKAIDELRGGETVNDPNAEEQRQA
LEKYTLDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKNKRLLAL
DMGALIAGAKYRGEFEERLKGVLNDLAKQEGQIILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYEVHHGVEITDPALVAAATLSHRYISDRQLPDKAIDLIDEAASL
IRMEIDSKPESMDKLERRLIQLKIEREALKKENDEASKKRLVDLQKSIDELEQNYSDLEEIWKAEKATMQGSTQIKEALE
QAKLEMETARRAGDLSRMSELQYGRIPELEKRLSQVSSVDAMETKLVRNKVTEDEIAEVVSKWTGIPVSKMMEGEKEKLL
KMEEALHSRLIGQNEAVDAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALASFLFDTEEAMVRIDMSEFMEK
HSVARLIGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHTDVFNILLQVMDDGRLTDGQGRTVDFRNTVIVMTSNL
GSQLIQEMSSKFNYDEIKAAVMDLVSQHFRPEFINRIDESVVFHSLTKEQIAKIAAIQINYLHHRLKQQNITLEVTSEAL
SHLAEAGFDPVYGARPLKRTIQQKLENPLAQSLLTGKFKSGDTIIVSYKDGVMEFSKR

Nucleotide

• Length: 2577 bp

>NTDB_id=149350 A1D13_RS08875 WP_027219801.1 1938391..1940967(+) (clpC) [Legionella pneumophila strain F4468]
ATGCGAATGGACAAACTAACATCAAAGTTTCAAATGGCTCTTGCAGATGCCCAATCCCTGGCTTTAGGTAGAGACAATGG
ATTTATAGAACCAGAACATTTAATGAAAGCCTTGCTTGATCAGCAAGGCGGAAGTTGCAGACCTCTTCTCAGTAAAGCGG
GTGTTAATATACCACTATTAAGAACTTTAATTGACCAAGCTCTGGATAAACTACCAAAAGTATCAGGCACCGGAGGAGAT
ATTCATATATCTAATGCATTGAATAGACTACTTAACCTGACTGACAAACTATCGCAACAAAGAAAAGATAACTTTATTTC
AAGCGAGCTTTTTGTATTAGCAGCGATAAATGAGGATAGTAACCTTGCAAAAATACTCAAACAAGCCGGGGGTGACAACA
AAGCAATTGAAAAAGCGATTGATGAGTTAAGAGGTGGAGAAACGGTTAATGATCCAAATGCAGAGGAACAGCGACAAGCT
CTTGAAAAATATACGCTGGATCTGACTGAACGTGCCGAGCAAGGAAAATTGGATCCAGTGATTGGACGAGATGATGAAAT
CAGACGCACCATCCAGGTATTGCAAAGAAGAACCAAAAATAACCCTGTATTAATAGGTGAGCCTGGTGTTGGTAAAACAG
CCATAGTAGAAGGTTTGGCACAACGAATTATTAATGGTGAAGTACCTGAAGGATTAAAGAATAAACGCTTACTAGCACTG
GACATGGGTGCCTTGATCGCAGGTGCAAAATATCGTGGAGAGTTTGAAGAACGTTTAAAAGGTGTGCTTAATGATTTGGC
AAAACAAGAGGGTCAAATCATATTATTTATTGATGAATTACACACTATGGTTGGCGCTGGCAAGGCTGAAGGAGCTATGG
ATGCTGGGAATATGCTCAAACCAGCATTGGCTAGAGGTGAATTGCATTGCATTGGGGCTACGACATTAGACGAATACCGA
CAATACATTGAAAAGGATGCTGCTCTTGAACGACGCTTTCAAAAAGTACTGGTCGATGAACCCAGTGTGGAAGACACTAT
CGCTATATTAAGGGGACTTAAGGAACGTTACGAAGTTCACCATGGAGTTGAAATTACAGATCCCGCTTTGGTTGCTGCAG
CAACGCTATCCCATCGTTACATCAGCGACCGTCAACTACCTGATAAGGCCATTGATTTAATTGACGAAGCCGCCAGCTTA
ATCCGGATGGAAATTGATTCAAAACCAGAAAGTATGGATAAACTGGAACGACGCTTGATTCAGCTAAAAATCGAGCGTGA
AGCATTGAAAAAGGAAAATGACGAAGCGTCTAAAAAAAGACTTGTTGATTTACAAAAAAGTATCGATGAATTAGAGCAAA
ATTATTCAGACTTAGAAGAAATTTGGAAAGCTGAAAAAGCGACCATGCAAGGATCCACTCAAATCAAAGAAGCACTTGAG
CAAGCCAAACTGGAAATGGAAACTGCAAGGAGAGCAGGAGATTTAAGTCGTATGTCCGAATTACAATATGGACGTATACC
CGAGCTGGAAAAAAGATTAAGCCAGGTCTCTTCCGTCGATGCTATGGAAACAAAGTTGGTACGCAATAAAGTCACCGAAG
ATGAGATCGCAGAAGTTGTTTCAAAATGGACAGGAATCCCAGTATCTAAAATGATGGAAGGAGAAAAGGAAAAACTGCTG
AAAATGGAAGAAGCTTTGCACAGTAGACTCATTGGCCAGAATGAAGCGGTGGATGCTGTTTCTAATGCCATAAGACGGTC
ACGCGCAGGCCTGTCTGATCCTAATCGTCCAATTGGTTCATTTCTTTTTCTGGGGCCAACTGGTGTGGGAAAAACTGAAC
TATGTAAAGCACTTGCTTCTTTTCTTTTTGATACGGAAGAGGCGATGGTGCGCATTGATATGTCTGAATTTATGGAAAAA
CACTCTGTTGCGCGCTTAATCGGAGCACCTCCTGGCTATGTAGGATATGAGGAGGGTGGCTATTTAACTGAAGCAGTCAG
ACGCAGGCCCTATTCTGTTATCTTACTTGATGAAGTAGAAAAAGCTCATACAGATGTATTTAATATTCTGCTTCAAGTGA
TGGATGATGGCCGTCTAACAGATGGTCAGGGACGTACTGTTGACTTTAGGAATACCGTTATTGTTATGACCTCTAATCTG
GGATCTCAACTCATTCAGGAAATGAGCAGCAAATTTAATTACGATGAGATTAAGGCTGCGGTAATGGATTTAGTCAGCCA
ACATTTCAGACCTGAATTTATCAACAGAATTGATGAATCGGTGGTATTCCATTCCCTGACAAAAGAACAAATTGCAAAAA
TTGCAGCAATCCAGATTAACTATTTACATCATCGGCTGAAACAACAAAACATCACTCTTGAAGTCACAAGTGAGGCTTTA
TCTCATTTGGCTGAAGCAGGATTTGATCCGGTCTATGGTGCCCGCCCCCTAAAACGTACTATTCAGCAAAAATTAGAGAA
TCCCTTAGCTCAATCATTATTGACTGGAAAATTTAAATCAGGAGATACCATTATTGTATCTTATAAAGACGGAGTAATGG
AATTTTCCAAGCGATGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (203-335)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-846)

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-145)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.066	100	0.477
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.061	100	0.415
clpC	Lactococcus lactis subsp. cremoris KW2	46.454	80.536	0.374
clpE	Streptococcus pneumoniae D39	45.428	80.303	0.365
clpE	Streptococcus pneumoniae R6	45.428	80.303	0.365
clpE	Streptococcus pneumoniae TIGR4	45.428	80.303	0.365
clpE	Streptococcus pneumoniae Rx1	45.428	80.303	0.365
clpE	Streptococcus mutans UA159	46.097	79.138	0.365