Detailed information NTG0149187

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: AS588_RS13555
• Genome accession: NZ_CP014700
• Coordinates: 2848139..2849221 (-)
• Length: 360 a.a.
• NCBI ID: WP_003156401.1
• Uniprot ID: A0AAI8HS26
• Organism: Bacillus amyloliquefaciens strain S499
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2843139..2854221

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AS588_RS13530 (AS588_13530)	cysE	2843238..2843891 (-)	654	WP_003156410.1	serine O-acetyltransferase	-
AS588_RS13535 (AS588_13535)	gltX	2844202..2845653 (-)	1452	WP_015388783.1	glutamate--tRNA ligase	-
AS588_RS13540 (AS588_13540)	ispF	2845745..2846221 (-)	477	WP_003156407.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
AS588_RS13545 (AS588_13545)	ispD	2846214..2846912 (-)	699	WP_003156405.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
AS588_RS13550 (AS588_13550)	-	2846925..2848025 (-)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
AS588_RS13555 (AS588_13555)	disA	2848139..2849221 (-)	1083	WP_003156401.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
AS588_RS13560 (AS588_13560)	radA/sms	2849225..2850604 (-)	1380	WP_015388784.1	DNA repair protein RadA	Machinery gene
AS588_RS13565 (AS588_13565)	clpC	2850698..2853130 (-)	2433	WP_007410388.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
AS588_RS13570 (AS588_13570)	-	2853127..2854218 (-)	1092	WP_003156398.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40671.21 Da
• Isoelectric Point: 5.5321

>NTDB_id=149187 AS588_RS13555 WP_003156401.1 2848139..2849221(-) (disA) [Bacillus amyloliquefaciens strain S499]
MEKEKKGAKQELDLSAILQFVAPGTPLRAGIENVLRANTGGLIVVGYNDKVKQVVDGGFHINTSFAPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPEATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQDSMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTITALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIRLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSILFKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGFLPS
ITEATVEELDDVEGIGEVRAQKIKKGLKRLQEKHYIDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=149187 AS588_RS13555 WP_003156401.1 2848139..2849221(-) (disA) [Bacillus amyloliquefaciens strain S499]
ATGGAAAAAGAGAAAAAAGGGGCGAAACAAGAGCTTGACCTGTCTGCAATTCTGCAGTTCGTTGCACCGGGCACCCCGCT
CAGAGCCGGGATAGAGAATGTACTTCGGGCAAATACAGGCGGCCTGATTGTTGTCGGATACAATGATAAGGTAAAGCAAG
TCGTGGATGGCGGTTTTCATATTAATACATCATTTGCGCCCGCTCACTTATACGAGCTGGCCAAAATGGACGGTGCCATT
ATTTTAAGTGATTCCGGCCAGAAAATTCTTTATGCGAATACGCAGCTTATGCCGGAGGCGACCATTTCTTCTTCAGAAAC
GGGAATGAGGCACCGTACGGCGGAACGGGTGGCGAAGCAGACCGGCTGTCTCGTCATCGCCATTTCTGAGCGCAGAAATG
TCATTACGTTATATCAGGACAGCATGAAGTACACACTAAAGGACATAGGTTTTATTTTAACAAAGGCAAATCAGGCCATT
CAAACGCTCGAGAAGTATAAAACCATTTTAGACAAAACAATTACGGCTCTAAACGCGTTAGAGTTTGAGGAGCTTGTGAC
ATTCAGTGACGTGCTGTCTGTCATGCATCGGTATGAAATGGTGCTCCGAATAAAAAATGAAATCAATATGTATATTAAAG
AACTCGGAACGGAAGGCCACTTAATCCGTCTGCAGGTGATTGAACTGATTACGGACATGGAAGAAGAGGCGGCACTTTTC
ATCAAAGACTATGTCAAAGAAAAAATCAAAGATCCGTTCGTGCTGTTAAAAGAGCTCCAGGATATGTCCAGCTATGATCT
GCTGGATGATTCCATTCTGTTTAAACTGCTTGGATACCCGGCTTCTACGAATCTTGATGATTATGTGCTCCCGAGAGGCT
ACAGGCTGCTGAACAAAATTCCGCGTCTGCCGATGCCGATTGTTGAAAATGTGGTTGAGGCGTTCGGATTTTTGCCAAGC
ATAACGGAAGCCACTGTAGAAGAGCTTGATGATGTCGAGGGTATCGGCGAAGTGCGCGCCCAAAAAATCAAAAAAGGCTT
AAAACGCCTTCAGGAAAAACACTATATAGATAGACAGCTTTAA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: A0AAI8HS26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	94.444	100	0.944