Detailed information NTG0147414

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB179_RS14035
• Genome accession: NZ_CP011685
• Coordinates: 2746375..2747262 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain ZJ5499
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2741375..2752262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB179_RS14000 (AB179_14005)	-	2741394..2741486 (+)	93	WP_010956583.1	hypothetical protein	-
AB179_RS14005 (AB179_14010)	-	2741594..2742091 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB179_RS14010 (AB179_14015)	-	2742101..2742361 (-)	261	WP_001791974.1	hypothetical protein	-
AB179_RS14015 (AB179_14020)	-	2742743..2742856 (-)	114	Protein_2678	hypothetical protein	-
AB179_RS14025 (AB179_14030)	-	2743515..2745515 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB179_RS14030 (AB179_14035)	-	2745512..2746267 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB179_RS14035 (AB179_14040)	braS	2746375..2747262 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB179_RS14040 (AB179_14045)	braR	2747273..2747938 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB179_RS14045 (AB179_14050)	-	2747964..2748164 (-)	201	WP_000604730.1	hypothetical protein	-
AB179_RS14055 (AB179_14060)	-	2748362..2749786 (+)	1425	WP_063653204.1	alkaline phosphatase	-
AB179_RS15630	-	2749846..2749947 (-)	102	WP_000731976.1	SE2200 family small protein	-
AB179_RS14060 (AB179_14065)	-	2750069..2750524 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB179_RS14065 (AB179_14070)	-	2750769..2751530 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=147414 AB179_RS14035 WP_000143425.1 2746375..2747262(-) (braS) [Staphylococcus aureus strain ZJ5499]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=147414 AB179_RS14035 WP_000143425.1 2746375..2747262(-) (braS) [Staphylococcus aureus strain ZJ5499]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1