Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | AB179_RS00290 | Genome accession | NZ_CP011685 |
| Coordinates | 63303..64931 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain ZJ5499 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 58160..101807 | 63303..64931 | within | 0 |
| SCCmec | 44911..66302 | 63303..64931 | within | 0 |
Gene organization within MGE regions
Location: 44911..101807
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AB179_RS00195 (AB179_00195) | mecA | 44911..46920 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| AB179_RS00200 (AB179_00200) | mecR1 | 47017..48774 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| AB179_RS00205 (AB179_00205) | mecI | 48774..49145 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| AB179_RS15125 | psm-mec | 49230..49298 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| AB179_RS00210 (AB179_00210) | - | 49632..50762 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| AB179_RS00220 (AB179_00220) | cstB | 50876..52210 (-) | 1335 | Protein_40 | persulfide dioxygenase-sulfurtransferase CstB | - |
| AB179_RS00225 (AB179_00225) | - | 52243..53307 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| AB179_RS00230 (AB179_00230) | cstR | 53443..53703 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| AB179_RS00235 (AB179_00235) | - | 53703..54341 (+) | 639 | Protein_43 | sulfite exporter TauE/SafE family protein | - |
| AB179_RS15585 | - | 54395..54454 (-) | 60 | Protein_44 | DNA repair protein RadC | - |
| AB179_RS00240 (AB179_00240) | - | 54686..55348 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| AB179_RS15590 | - | 55740..55799 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| AB179_RS00245 (AB179_00245) | erm(A) | 55907..56638 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| AB179_RS00250 (AB179_00250) | - | 56764..57546 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| AB179_RS00255 (AB179_00255) | - | 57697..58074 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| AB179_RS00260 (AB179_00260) | - | 58081..59974 (-) | 1894 | Protein_50 | site-specific integrase | - |
| AB179_RS00265 (AB179_00265) | - | 59971..61056 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| AB179_RS00270 (AB179_00270) | - | 61175..61492 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| AB179_RS00275 (AB179_00275) | - | 61513..62019 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| AB179_RS00280 (AB179_00280) | - | 62037..62348 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| AB179_RS00285 (AB179_00285) | - | 62435..62785 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| AB179_RS00290 (AB179_00290) | ccrB | 63303..64931 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| AB179_RS00295 (AB179_00295) | ccrA | 64953..66302 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| AB179_RS00300 (AB179_00300) | cch1 | 66536..68329 (-) | 1794 | WP_000195100.1 | cassette chromosome replicative helicase | - |
| AB179_RS00305 (AB179_00305) | ssb | 68329..68625 (-) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| AB179_RS00310 (AB179_00310) | - | 68818..69864 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| AB179_RS14525 | - | 70115..71256 (-) | 1142 | Protein_61 | IS3-like element ISSau4 family transposase | - |
| AB179_RS15505 | - | 71426..71560 (+) | 135 | WP_001792216.1 | hypothetical protein | - |
| AB179_RS00330 (AB179_00330) | - | 71767..72702 (-) | 936 | Protein_63 | YfcC family protein | - |
| AB179_RS00335 (AB179_00335) | - | 73415..74110 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| AB179_RS00340 (AB179_00340) | - | 74085..76754 (-) | 2670 | WP_000446429.1 | sensor histidine kinase | - |
| AB179_RS00345 (AB179_00345) | kdpF | 76921..77001 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| AB179_RS00350 (AB179_00350) | kdpA | 77022..78698 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| AB179_RS00355 (AB179_00355) | - | 78717..80738 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| AB179_RS00360 (AB179_00360) | - | 80754..81311 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| AB179_RS00365 (AB179_00365) | - | 81856..82725 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| AB179_RS00370 (AB179_00370) | - | 82735..83631 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| AB179_RS00380 (AB179_00380) | - | 84750..85376 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| AB179_RS00385 (AB179_00385) | - | 85491..86999 (+) | 1509 | WP_001001347.1 | protein kinase domain-containing protein | - |
| AB179_RS00390 (AB179_00390) | - | 87249..87383 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| AB179_RS00395 (AB179_00395) | - | 87347..87439 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| AB179_RS00400 (AB179_00400) | - | 87586..89331 (+) | 1746 | WP_063653119.1 | DUF6119 family protein | - |
| AB179_RS00405 (AB179_00405) | - | 89429..89784 (-) | 356 | Protein_77 | tRNA-dihydrouridine synthase | - |
| AB179_RS00410 (AB179_00410) | - | 90089..90177 (-) | 89 | Protein_78 | hypothetical protein | - |
| AB179_RS00415 (AB179_00415) | - | 90275..91030 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| AB179_RS00420 (AB179_00420) | cstR | 91030..91290 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| AB179_RS00425 (AB179_00425) | cstA | 91427..92491 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| AB179_RS00430 (AB179_00430) | cstB | 92522..93856 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| AB179_RS00435 (AB179_00435) | sqr | 93875..95068 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| AB179_RS15565 | - | 95335..95549 (-) | 215 | Protein_84 | universal stress protein | - |
| AB179_RS00445 (AB179_00445) | - | 95735..96721 (-) | 987 | WP_000662022.1 | tRNA dihydrouridine synthase | - |
| AB179_RS00450 (AB179_00450) | - | 97030..97233 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| AB179_RS00455 (AB179_00455) | - | 97282..97578 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| AB179_RS00460 (AB179_00460) | - | 97786..98388 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| AB179_RS00465 (AB179_00465) | - | 98655..101807 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=147374 AB179_RS00290 WP_001186602.1 63303..64931(-) (ccrB) [Staphylococcus aureus strain ZJ5499]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=147374 AB179_RS00290 WP_001186602.1 63303..64931(-) (ccrB) [Staphylococcus aureus strain ZJ5499]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |