Detailed information NTG0146623

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AA076_RS13540
• Genome accession: NZ_CP011526
• Coordinates: 2651436..2652323 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain DSM 20231
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2646436..2657323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AA076_RS15795 (AA076_13505)	-	2646455..2646547 (+)	93	WP_010956583.1	hypothetical protein	-
AA076_RS13510 (AA076_13510)	-	2646655..2647152 (-)	498	WP_001065268.1	glutathione peroxidase	-
AA076_RS15800 (AA076_13515)	-	2647162..2647422 (-)	261	WP_001789910.1	hypothetical protein	-
AA076_RS15810 (AA076_13520)	-	2647804..2647917 (-)	114	WP_011447078.1	hypothetical protein	-
AA076_RS13530 (AA076_13530)	-	2648576..2650576 (-)	2001	WP_000776751.1	ABC transporter permease	-
AA076_RS13535 (AA076_13535)	-	2650573..2651328 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AA076_RS13540 (AA076_13540)	braS	2651436..2652323 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AA076_RS13545 (AA076_13545)	braR	2652334..2652999 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AA076_RS13550 (AA076_13550)	-	2653025..2653225 (-)	201	WP_000604728.1	hypothetical protein	-
AA076_RS13560 (AA076_13560)	-	2653423..2654847 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AA076_RS16215	-	2654907..2655008 (-)	102	WP_000731972.1	SE2200 family small protein	-
AA076_RS13565 (AA076_13565)	-	2655130..2655585 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AA076_RS13570 (AA076_13570)	-	2655830..2656591 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=146623 AA076_RS13540 WP_000143419.1 2651436..2652323(-) (braS) [Staphylococcus aureus strain DSM 20231]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=146623 AA076_RS13540 WP_000143419.1 2651436..2652323(-) (braS) [Staphylococcus aureus strain DSM 20231]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997