Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AA076_RS10255 Genome accession   NZ_CP011526
Coordinates   2028427..2029143 (+) Length   238 a.a.
NCBI ID   WP_001836294.1    Uniprot ID   -
Organism   Staphylococcus aureus strain DSM 20231     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023427..2034143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA076_RS10225 (AA076_10225) - 2023646..2024272 (+) 627 WP_000522384.1 nitroreductase family protein -
  AA076_RS10230 (AA076_10230) - 2024633..2025418 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  AA076_RS16205 hld 2026015..2026095 (-) 81 WP_000046022.1 delta-hemolysin -
  AA076_RS10240 (AA076_10240) agrB 2026385..2026954 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  AA076_RS10245 (AA076_10245) agrD 2026951..2027091 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  AA076_RS10250 (AA076_10250) agrC 2027116..2028408 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  AA076_RS10255 (AA076_10255) agrA 2028427..2029143 (+) 717 WP_001836294.1 quorum-sensing response regulator AgrA Regulator
  AA076_RS15370 (AA076_10260) - 2029215..2029322 (+) 108 WP_001790167.1 hypothetical protein -
  AA076_RS10265 (AA076_10265) - 2029510..2030469 (-) 960 WP_001253312.1 carbohydrate kinase -
  AA076_RS10270 (AA076_10270) - 2030466..2031950 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  AA076_RS10275 (AA076_10275) - 2032099..2033049 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27906.89 Da        Isoelectric Point: 5.8625

>NTDB_id=146619 AA076_RS10255 WP_001836294.1 2028427..2029143(+) (agrA) [Staphylococcus aureus strain DSM 20231]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHDSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=146619 AA076_RS10255 WP_001836294.1 2028427..2029143(+) (agrA) [Staphylococcus aureus strain DSM 20231]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATGATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment