Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   AA974_RS06370 Genome accession   NZ_CP011487
Coordinates   1310225..1310506 (-) Length   93 a.a.
NCBI ID   WP_001272686.1    Uniprot ID   G2MDJ3
Organism   Helicobacter pylori strain PNG84A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1305225..1315506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA974_RS06350 (AA974_06380) - 1305930..1307270 (-) 1341 WP_064433860.1 COG3014 family protein -
  AA974_RS06360 (AA974_06385) comB4 1307597..1309960 (-) 2364 WP_064433861.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  AA974_RS06365 (AA974_06390) comB3 1309962..1310225 (-) 264 WP_000584970.1 hypothetical protein Machinery gene
  AA974_RS06370 (AA974_06395) comB2 1310225..1310506 (-) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  AA974_RS06375 (AA974_06400) - 1310652..1311479 (-) 828 WP_064433862.1 DUF5718 family protein -
  AA974_RS06380 (AA974_06405) - 1311571..1312623 (-) 1053 WP_064433863.1 MnmA/TRMU family protein -
  AA974_RS06385 (AA974_06410) dnaG 1312620..1314299 (-) 1680 WP_064433864.1 DNA primase -
  AA974_RS06390 (AA974_06415) groES 1314583..1314939 (+) 357 WP_024774040.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10539.81 Da        Isoelectric Point: 9.1450

>NTDB_id=146307 AA974_RS06370 WP_001272686.1 1310225..1310506(-) (comB2) [Helicobacter pylori strain PNG84A]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=146307 AA974_RS06370 WP_001272686.1 1310225..1310506(-) (comB2) [Helicobacter pylori strain PNG84A]
ATGTCCGCTCATTTTTTAAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGTTTGTTCGCTGAAGGGTTAGAAGGGTT
TTTTAACGCCCTAGAAGCCCAGCTCAAAAGCCCCATCGCTAAGGGGATTTTAATGGTGATTTTCATAGGGATCGCTATTT
ATGTGTGGAGGAATTTAGACCGGTGGAAAGAGATTTTATTCACGATCCTTGGCGTGGTGTTTGGGATTTTTTTATTCTTT
AAAGCCCCGAGCTTAGCGAATTGGTTTATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2MDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

98.925

100

0.989

Multiple sequence alignment