Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   AA974_RS06360 Genome accession   NZ_CP011487
Coordinates   1307597..1309960 (-) Length   787 a.a.
NCBI ID   WP_064433861.1    Uniprot ID   -
Organism   Helicobacter pylori strain PNG84A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1302597..1314960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA974_RS06335 (AA974_06365) lpxE 1303068..1303640 (+) 573 WP_064433857.1 lipid A 1-phosphatase LpxE -
  AA974_RS06340 (AA974_06370) nspC 1303650..1304867 (-) 1218 WP_064433858.1 carboxynorspermidine decarboxylase -
  AA974_RS06345 (AA974_06375) cheV1 1304864..1305829 (-) 966 WP_064433859.1 chemotaxis protein CheV1 -
  AA974_RS06350 (AA974_06380) - 1305930..1307270 (-) 1341 WP_064433860.1 COG3014 family protein -
  AA974_RS06360 (AA974_06385) comB4 1307597..1309960 (-) 2364 WP_064433861.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  AA974_RS06365 (AA974_06390) comB3 1309962..1310225 (-) 264 WP_000584970.1 hypothetical protein Machinery gene
  AA974_RS06370 (AA974_06395) comB2 1310225..1310506 (-) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  AA974_RS06375 (AA974_06400) - 1310652..1311479 (-) 828 WP_064433862.1 DUF5718 family protein -
  AA974_RS06380 (AA974_06405) - 1311571..1312623 (-) 1053 WP_064433863.1 MnmA/TRMU family protein -
  AA974_RS06385 (AA974_06410) dnaG 1312620..1314299 (-) 1680 WP_064433864.1 DNA primase -
  AA974_RS06390 (AA974_06415) groES 1314583..1314939 (+) 357 WP_024774040.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90232.83 Da        Isoelectric Point: 8.8672

>NTDB_id=146305 AA974_RS06360 WP_064433861.1 1307597..1309960(-) (comB4) [Helicobacter pylori strain PNG84A]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTDQLQDLFTERQMALD
SLEKVVARLVVKRRKMDYQQNIQSDSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSQEVLNFYAEYVNGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGVLLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEGLDTQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKETARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLTPSRDKEALEDMNAILSAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNAKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPIEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=146305 AA974_RS06360 WP_064433861.1 1307597..1309960(-) (comB4) [Helicobacter pylori strain PNG84A]
ATGTTAGAAAAGCTTTTAAGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAAGGGGTTAGCTACACCCATTTAAGCACAGATCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATGGATTACCAACAAAACATTCAATCTGATTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCTC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGACATTCTCTCT
TATAAGGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAATTATGCTCCCAAACTCTTAAGCTC
TCAAGAGGTTTTGAATTTTTATGCGGAATACGTTAACGGGTTCGATCTACCCTTAAAGCCTCTAGTAGGGGGGTATTTGA
GCGATAGTTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAAAGGATCACTTCTATAGCGATCGGAGTGCTTTTATACCAAGAGACGCC
TTTAGACATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAATTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAGGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
TTAAATATTCTTATCAAAGCCCCTAGTTTAGAAGGTTTAGACACTCAAACAAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAATTTGGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTTCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTAACTTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATCTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAACCGCCAGAGTGAATGGGCATACTCTAATCATAGGGGCTACCGGGAGTGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCATTTGATAGGATGCAGGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTACCCCTTCAAGGGATAAAGAAGCCTTGG
AAGACATGAATGCGATTTTGAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCTTTTAGTTTGTTGGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCATTCAACTCCAACGCTTTTTTAAATGTGATAAACTTAGACGCTATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCTAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACGCTAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAACTCAGTGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGAAATTCTAACATGATTGATGT
GAGTTTGGAAAGCTTAGGGCGTTATTTGAAAATTTTTAATTCGGATTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTATAGAGTGGCGTGAGAAACTTCTGAAAAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(425-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.078

100

0.971

Multiple sequence alignment